Econazole_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Econazole perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Econazole_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
AKAP12 A kinase (PRKA) anchor protein 12 0.099315
ZMYND8 zinc finger, MYND-type containing 8 0.0934681
LDHA lactate dehydrogenase A 0.0738399
ERRFI1 ERBB receptor feedback inhibitor 1 0.0715576
MT2A metallothionein 2A 0.0628143
MBNL1 muscleblind-like splicing regulator 1 0.0624059
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0622202
FKBP5 FK506 binding protein 5 0.0538207
ESYT2 extended synaptotagmin-like protein 2 0.0512372
ANGPTL4 angiopoietin-like 4 0.0510785
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0504006
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.04974
TXNIP thioredoxin interacting protein 0.049288
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.048187
MT1X metallothionein 1X 0.0410572
HMGA2 high mobility group AT-hook 2 0.0406892
BASP1 brain abundant, membrane attached signal protein 1 0.0397438
EFNA5 ephrin-A5 0.0388826
ANKRD28 ankyrin repeat domain 28 0.0384646
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.038339
ZBTB38 zinc finger and BTB domain containing 38 0.0363755
DUSP12 dual specificity phosphatase 12 0.0354537
MBNL2 muscleblind-like splicing regulator 2 0.0338294
RAD23B RAD23 homolog B (S. cerevisiae) 0.0337526
TMSB10 thymosin beta 10 0.0327885
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0312175
POTEF POTE ankyrin domain family, member F 0.0309173
AKAP13 A kinase (PRKA) anchor protein 13 0.0297769
TOP1 topoisomerase (DNA) I 0.0297767
PABPC1 poly(A) binding protein, cytoplasmic 1 0.0285124
KLF9 Kruppel-like factor 9 0.028253
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0281743
MYOF myoferlin 0.0279257
SET SET nuclear proto-oncogene 0.0279093
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0277321
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.027661
WAC WW domain containing adaptor with coiled-coil 0.0272862
CAPRIN2 caprin family member 2 0.0271027
ACTN1 actinin, alpha 1 0.0270458
DNER delta/notch-like EGF repeat containing 0.0265335
MORF4L2 mortality factor 4 like 2 0.0255959
UBE2H ubiquitin-conjugating enzyme E2H 0.0246719
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0246543
JAK1 Janus kinase 1 0.0243204
SRGN serglycin 0.0240409
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0235272
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0232148
TPX2 TPX2, microtubule-associated 0.0228983
PER1 period circadian clock 1 0.0227364
CALU calumenin 0.0226608
PTPRG protein tyrosine phosphatase, receptor type, G 0.0221204
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.0218931
PNISR PNN-interacting serine/arginine-rich protein 0.0217269
SUZ12 SUZ12 polycomb repressive complex 2 subunit 0.0214747
UBC ubiquitin C 0.0212371
LATS2 large tumor suppressor kinase 2 0.0211625
NPAS2 neuronal PAS domain protein 2 0.0210624
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 0.0209539
RPS4X ribosomal protein S4, X-linked 0.0209317
UBQLN1 ubiquilin 1 0.020472
NACA nascent polypeptide-associated complex alpha subunit 0.0202156
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0200957
TAOK3 TAO kinase 3 0.0199006
FLNA filamin A, alpha 0.0198865
OCIAD1 OCIA domain containing 1 0.0198769
ZFHX3 zinc finger homeobox 3 0.0197669
RPL26 ribosomal protein L26 0.0197544
ENO1 enolase 1, (alpha) 0.0195543
PCBP2 poly(rC) binding protein 2 0.0194144
SIK3 SIK family kinase 3 0.0192342
CCND3 cyclin D3 0.0192309
ZFYVE16 zinc finger, FYVE domain containing 16 0.0190001
PRR16 proline rich 16 0.0186092
KIF5B kinesin family member 5B 0.0185919
AKAP9 A kinase (PRKA) anchor protein 9 0.0184119
MKI67 marker of proliferation Ki-67 0.0183116
MYO9B myosin IXB 0.0182078
FOXO3 forkhead box O3 0.0181266
ZBTB16 zinc finger and BTB domain containing 16 0.018051
PRRC2C proline-rich coiled-coil 2C 0.017982
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.0179301
KIF23 kinesin family member 23 0.0176656
TNRC6A trinucleotide repeat containing 6A 0.0175605
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 0.0175088
TM9SF2 transmembrane 9 superfamily member 2 0.017298
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0172941
EEF2 eukaryotic translation elongation factor 2 0.0171766
NCOA6 nuclear receptor coactivator 6 0.0170115
SHPRH SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase 0.0168288
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.0167627
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.0167225
CALR calreticulin 0.0167203
PRPF4B pre-mRNA processing factor 4B 0.0163757
USP53 ubiquitin specific peptidase 53 0.016331
TMEM39A transmembrane protein 39A 0.0162447
CEP70 centrosomal protein 70kDa 0.0162351
SLC26A2 solute carrier family 26 (anion exchanger), member 2 0.0161735
ARID1A AT rich interactive domain 1A (SWI-like) 0.0160843
LDLRAD3 low density lipoprotein receptor class A domain containing 3 0.0160098
DUSP6 dual specificity phosphatase 6 0.0159345

decreased expression

Symbol Name Standardized Value
TRIO trio Rho guanine nucleotide exchange factor -0.095475
CD44 CD44 molecule (Indian blood group) -0.0892246
FNDC3B fibronectin type III domain containing 3B -0.0790255
LOC112694756 uncharaterized LOC112694756 -0.0757649
PHLDB2 pleckstrin homology-like domain, family B, member 2 -0.0722979
VIM vimentin -0.069883
OSMR oncostatin M receptor -0.0654577
SMAD3 SMAD family member 3 -0.0616636
DSCAM Down syndrome cell adhesion molecule -0.0603323
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0600438
NCEH1 neutral cholesterol ester hydrolase 1 -0.0543156
JMJD1C jumonji domain containing 1C -0.0528465
TPT1 tumor protein, translationally-controlled 1 -0.0487906
NDRG1 N-myc downstream regulated 1 -0.0448353
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0427372
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0426414
MAP1B microtubule-associated protein 1B -0.0425287
ZBTB20 zinc finger and BTB domain containing 20 -0.0424921
ANXA2 annexin A2 -0.0423942
RAD51B RAD51 paralog B -0.0420031
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0402485
VCL vinculin -0.0401973
TAS2R14 taste receptor, type 2, member 14 -0.0399887
AHNAK AHNAK nucleoprotein -0.0396287
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0395418
PBX3 pre-B-cell leukemia homeobox 3 -0.0393746
NAV2 neuron navigator 2 -0.03849
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0384547
SVIL supervillin -0.0382983
IER3 immediate early response 3 -0.0378065
SMYD3 SET and MYND domain containing 3 -0.0375414
PTK2 protein tyrosine kinase 2 -0.0373291
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0368671
SOD2 superoxide dismutase 2, mitochondrial -0.0367045
BIRC2 baculoviral IAP repeat containing 2 -0.0360252
COPB1 coatomer protein complex, subunit beta 1 -0.0359385
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0351801
NT5E 5'-nucleotidase, ecto (CD73) -0.0348172
PARD3 par-3 family cell polarity regulator -0.0343796
RIGI RNA sensor RIG-I -0.0341914
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -0.0341557
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0341391
IGFBP3 insulin-like growth factor binding protein 3 -0.0339125
WSB1 WD repeat and SOCS box containing 1 -0.0339125
RORA RAR-related orphan receptor A -0.0332282
PDE8A phosphodiesterase 8A -0.0330769
MACF1 microtubule-actin crosslinking factor 1 -0.0321596
RBM39 RNA binding motif protein 39 -0.0318593
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0316863
TXNRD1 thioredoxin reductase 1 -0.031659
TPM4 tropomyosin 4 -0.031421
MAPKAP1 mitogen-activated protein kinase associated protein 1 -0.0313626
NGLY1 N-glycanase 1 -0.0313024
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0311537
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0309424
FAF2 Fas associated factor family member 2 -0.0305477
MAP3K2 mitogen-activated protein kinase kinase kinase 2 -0.0303817
GBE1 glucan (1,4-alpha-), branching enzyme 1 -0.0303223
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0300312
FBXL2 F-box and leucine-rich repeat protein 2 -0.0297934
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.029539
IFIH1 interferon induced with helicase C domain 1 -0.0292434
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.0291628
HLA-C major histocompatibility complex, class I, C -0.0290054
RPLP1 ribosomal protein, large, P1 -0.0288582
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -0.0286209
TTC3 tetratricopeptide repeat domain 3 -0.028253
KLF7 Kruppel-like factor 7 (ubiquitous) -0.0274751
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0273639
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0273224
ANO6 anoctamin 6 -0.0271993
SDC4 syndecan 4 -0.0271922
BZW1 basic leucine zipper and W2 domains 1 -0.0270288
N4BP2L2 NEDD4 binding protein 2-like 2 -0.027
RPL4 ribosomal protein L4 -0.0266783
ZFAND3 zinc finger, AN1-type domain 3 -0.0263745
KMT2E lysine (K)-specific methyltransferase 2E -0.0261412
CDCP1 CUB domain containing protein 1 -0.0260738
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase -0.0257928
KIAA1328 KIAA1328 -0.0257155
ASPH aspartate beta-hydroxylase -0.025654
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0251255
HDAC9 histone deacetylase 9 -0.0244799
ANKRD12 ankyrin repeat domain 12 -0.0244491
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0244389
ZNF609 zinc finger protein 609 -0.0244379
MBD5 methyl-CpG binding domain protein 5 -0.0244313
AKT3 v-akt murine thymoma viral oncogene homolog 3 -0.0243471
THSD4 thrombospondin, type I, domain containing 4 -0.0241082
RTN4 reticulon 4 -0.0239411
CEP95 centrosomal protein 95kDa -0.0238817
TNRC18 trinucleotide repeat containing 18 -0.0237744
UBB ubiquitin B -0.0236951
SBF2 SET binding factor 2 -0.0235589
DTNA dystrobrevin, alpha -0.0235511
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0235021
HBP1 HMG-box transcription factor 1 -0.0234086
GNAS GNAS complex locus -0.0232839
USP34 ubiquitin specific peptidase 34 -0.0232354
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme -0.0232026