| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.147385 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.14544 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.139276 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.108482 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0964639 |
| FLNB | filamin B, beta | 0.0652274 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0592943 |
| MSN | moesin | 0.0583534 |
| NAV2 | neuron navigator 2 | 0.0583139 |
| SEPTIN9 | septin 9 | 0.0582403 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0520708 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0506261 |
| PRELID2 | PRELI domain containing 2 | 0.0491969 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0487565 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0487297 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0471785 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0446501 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0418364 |
| OPTN | optineurin | 0.041711 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0414933 |
| TPM3 | tropomyosin 3 | 0.0395477 |
| PLEC | plectin | 0.0388103 |
| CALR | calreticulin | 0.0386246 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0381403 |
| CENPF | centromere protein F, 350/400kDa | 0.0365286 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.036117 |
| INSIG2 | insulin induced gene 2 | 0.0356723 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.035663 |
| ADM | adrenomedullin | 0.0353459 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0349011 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0341875 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.034116 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0336195 |
| CD109 | CD109 molecule | 0.0330307 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0329651 |
| FLNA | filamin A, alpha | 0.0317216 |
| MYOF | myoferlin | 0.0316853 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0310312 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0305124 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0304915 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0295934 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0291458 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0289996 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0288428 |
| HELZ | helicase with zinc finger | 0.028467 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0284439 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0283616 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0280824 |
| PFKP | phosphofructokinase, platelet | 0.0279806 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.027962 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.027881 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0276798 |
| B2M | beta-2-microglobulin | 0.0276506 |
| SET | SET nuclear proto-oncogene | 0.0275152 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0275127 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0274994 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0273198 |
| DSPP | dentin sialophosphoprotein | 0.0267946 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0267062 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0265591 |
| RPL3 | ribosomal protein L3 | 0.0263621 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0261688 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0259655 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0257373 |
| PKM | pyruvate kinase, muscle | 0.0257072 |
| NDRG1 | N-myc downstream regulated 1 | 0.0254392 |
| SETD5 | SET domain containing 5 | 0.0254101 |
| VEGFA | vascular endothelial growth factor A | 0.0251632 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0249378 |
| DTNA | dystrobrevin, alpha | 0.0248848 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0243471 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0242817 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0242132 |
| CEP250 | centrosomal protein 250kDa | 0.0241745 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0241571 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0238171 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0237228 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0236459 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0235295 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0233794 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0233202 |
| PCBP2 | poly(rC) binding protein 2 | 0.0232548 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0231775 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0230437 |
| GOLGA4 | golgin A4 | 0.0228977 |
| TMSB4X | thymosin beta 4, X-linked | 0.0228622 |
| RPS2 | ribosomal protein S2 | 0.0228179 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0223829 |
| MSI2 | musashi RNA-binding protein 2 | 0.0223797 |
| HDAC9 | histone deacetylase 9 | 0.0222113 |
| COPA | coatomer protein complex, subunit alpha | 0.0220451 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0220014 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0218164 |
| FAM219A | family with sequence similarity 219, member A | 0.0217932 |
| FAM107B | family with sequence similarity 107, member B | 0.0215518 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0215411 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.0215245 |
| LMNA | lamin A/C | 0.0214707 |
| MMP12 | matrix metallopeptidase 12 | 0.0213557 |
| ZNF148 | zinc finger protein 148 | 0.0211338 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | -0.226554 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.163485 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.150945 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.147526 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.135731 |
| PODXL | podocalyxin-like | -0.132202 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.115242 |
| VIM | vimentin | -0.10616 |
| TMSB10 | thymosin beta 10 | -0.096576 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0964697 |
| ANXA2 | annexin A2 | -0.0881199 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0856968 |
| MAP1B | microtubule-associated protein 1B | -0.0840629 |
| THBS2 | thrombospondin 2 | -0.0815196 |
| CD44 | CD44 molecule (Indian blood group) | -0.0770503 |
| COL1A2 | collagen, type I, alpha 2 | -0.0755663 |
| COL3A1 | collagen, type III, alpha 1 | -0.0740888 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0735065 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0708592 |
| HLA-B | major histocompatibility complex, class I, B | -0.0634788 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0575104 |
| FBN1 | fibrillin 1 | -0.0562532 |
| MX2 | MX dynamin-like GTPase 2 | -0.0551107 |
| SUCNR1 | succinate receptor 1 | -0.0487598 |
| NAV1 | neuron navigator 1 | -0.0479956 |
| GLIS3 | GLIS family zinc finger 3 | -0.0475631 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0473544 |
| LOXL2 | lysyl oxidase-like 2 | -0.0463961 |
| HLA-C | major histocompatibility complex, class I, C | -0.0462732 |
| MEIS2 | Meis homeobox 2 | -0.0437726 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.042735 |
| HLA-E | major histocompatibility complex, class I, E | -0.0414029 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0402587 |
| CD99 | CD99 molecule | -0.0393267 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0383311 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0375031 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0372329 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0371532 |
| EHBP1 | EH domain binding protein 1 | -0.0367118 |
| S100A6 | S100 calcium binding protein A6 | -0.035511 |
| BSG | basigin (Ok blood group) | -0.0352121 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0349445 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0346592 |
| CANX | calnexin | -0.0343367 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0341281 |
| TAGLN2 | transgelin 2 | -0.0339786 |
| FRMD4A | FERM domain containing 4A | -0.0337044 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0327308 |
| CAVIN1 | caveolae associated protein 1 | -0.0327199 |
| RIGI | RNA sensor RIG-I | -0.0324293 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0319071 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0318288 |
| CCND1 | cyclin D1 | -0.0313897 |
| PXDN | peroxidasin | -0.031275 |
| NF1 | neurofibromin 1 | -0.0307039 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0306332 |
| PLAT | plasminogen activator, tissue | -0.0304461 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0296975 |
| VCL | vinculin | -0.0293093 |
| OSMR | oncostatin M receptor | -0.0286788 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0286655 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0285516 |
| MYADM | myeloid-associated differentiation marker | -0.0282873 |
| PARD3 | par-3 family cell polarity regulator | -0.028193 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0280988 |
| S100A10 | S100 calcium binding protein A10 | -0.0276837 |
| SYT1 | synaptotagmin I | -0.0272334 |
| PRRX1 | paired related homeobox 1 | -0.0272259 |
| VEGFC | vascular endothelial growth factor C | -0.0268317 |
| HDLBP | high density lipoprotein binding protein | -0.0267604 |
| FRMD5 | FERM domain containing 5 | -0.0263207 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0260958 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0259192 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0257736 |
| CDK6 | cyclin-dependent kinase 6 | -0.0255014 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.025484 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0253473 |
| LDHA | lactate dehydrogenase A | -0.0252636 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0251264 |
| JAZF1 | JAZF zinc finger 1 | -0.0247994 |
| AHNAK | AHNAK nucleoprotein | -0.0247283 |
| TCF12 | transcription factor 12 | -0.0246789 |
| NPR2 | natriuretic peptide receptor 2 | -0.0246426 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0244148 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0243628 |
| COL5A2 | collagen, type V, alpha 2 | -0.0242062 |
| RASAL2 | RAS protein activator like 2 | -0.0235824 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0235461 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0235358 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0234778 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0234092 |
| S100A4 | S100 calcium binding protein A4 | -0.0232511 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.023232 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0232296 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0228712 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0228388 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0228072 |
| TUBB | tubulin, beta class I | -0.0223019 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0222984 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0222788 |
