| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.138289 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.116386 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0784234 |
| ANXA1 | annexin A1 | 0.0739724 |
| DST | dystonin | 0.0739384 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0701783 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0629888 |
| RPL3 | ribosomal protein L3 | 0.0587127 |
| CPOX | coproporphyrinogen oxidase | 0.0554851 |
| TPM3 | tropomyosin 3 | 0.0549047 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0518748 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0503141 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0497517 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0488158 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0471405 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.046413 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0462313 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0448025 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.043179 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0427071 |
| XPOT | exportin, tRNA | 0.0425155 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.042163 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0406597 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0403058 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.040125 |
| CPNE1 | copine I | 0.0396527 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0389924 |
| TPI1 | triosephosphate isomerase 1 | 0.0373459 |
| EZR | ezrin | 0.0371526 |
| HDGF | hepatoma-derived growth factor | 0.0366382 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0356174 |
| SET | SET nuclear proto-oncogene | 0.0355573 |
| RPS2 | ribosomal protein S2 | 0.035186 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0344705 |
| DSPP | dentin sialophosphoprotein | 0.034346 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0337909 |
| RPS3 | ribosomal protein S3 | 0.0335973 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0334575 |
| PCBP2 | poly(rC) binding protein 2 | 0.0331111 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0325959 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0325347 |
| RPS12 | ribosomal protein S12 | 0.0324059 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0317568 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0311551 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0309231 |
| PNN | pinin, desmosome associated protein | 0.0306365 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0305441 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0303165 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0289761 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0286433 |
| KLC1 | kinesin light chain 1 | 0.028286 |
| NHSL1 | NHS-like 1 | 0.0281419 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0279391 |
| KIF5B | kinesin family member 5B | 0.0275908 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0275769 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0272921 |
| SETD5 | SET domain containing 5 | 0.0269323 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0266133 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0264918 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0259129 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0257752 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0256733 |
| CEP250 | centrosomal protein 250kDa | 0.0247376 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0244678 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0244086 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0244009 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.024367 |
| AHNAK | AHNAK nucleoprotein | 0.0243501 |
| PLEC | plectin | 0.0242969 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0241061 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0240541 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0238147 |
| YEATS2 | YEATS domain containing 2 | 0.023484 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0234082 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0234026 |
| RPL41 | ribosomal protein L41 | 0.0232309 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0230281 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0228491 |
| NCKAP1 | NCK-associated protein 1 | 0.0228445 |
| ZNF292 | zinc finger protein 292 | 0.0227155 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0226248 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0226143 |
| PRKCI | protein kinase C, iota | 0.0225811 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0224742 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0222016 |
| CDK19 | cyclin-dependent kinase 19 | 0.022146 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.0220392 |
| CEP70 | centrosomal protein 70kDa | 0.0220191 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.021975 |
| VMP1 | vacuole membrane protein 1 | 0.0216989 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0215085 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0212415 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0209771 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0208761 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0208013 |
| MSN | moesin | 0.0207051 |
| PCM1 | pericentriolar material 1 | 0.0206446 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0206249 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0205633 |
| MED13L | mediator complex subunit 13-like | 0.0204557 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.348821 |
| VIM | vimentin | -0.175132 |
| TMSB10 | thymosin beta 10 | -0.142574 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.130604 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0813074 |
| NLGN1 | neuroligin 1 | -0.0742215 |
| HMGA1 | high mobility group AT-hook 1 | -0.0726174 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0685994 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0587267 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0568617 |
| FTL | ferritin, light polypeptide | -0.0538725 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0531937 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0529256 |
| EGR1 | early growth response 1 | -0.0498625 |
| PCDH7 | protocadherin 7 | -0.0461185 |
| RPS24 | ribosomal protein S24 | -0.0450266 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0447439 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0439024 |
| RPLP1 | ribosomal protein, large, P1 | -0.0434351 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0419321 |
| ACTG1 | actin gamma 1 | -0.0405204 |
| RPL35A | ribosomal protein L35a | -0.0399661 |
| CCND1 | cyclin D1 | -0.0379835 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0379105 |
| ZNF804A | zinc finger protein 804A | -0.0366523 |
| POTEF | POTE ankyrin domain family, member F | -0.0357733 |
| TUBA1B | tubulin, alpha 1b | -0.0345184 |
| LDHA | lactate dehydrogenase A | -0.0337373 |
| RPLP0 | ribosomal protein, large, P0 | -0.0310515 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0307881 |
| RASAL2 | RAS protein activator like 2 | -0.0307777 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0300518 |
| BCHE | butyrylcholinesterase | -0.029292 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0291076 |
| RPS6 | ribosomal protein S6 | -0.0284118 |
| HMGB1 | high mobility group box 1 | -0.0284045 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0280775 |
| PFN1 | profilin 1 | -0.0280428 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.027933 |
| FUS | FUS RNA binding protein | -0.0277445 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0275052 |
| GCG | glucagon | -0.0256318 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0252356 |
| RPL38 | ribosomal protein L38 | -0.0250201 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0250011 |
| HMGA2 | high mobility group AT-hook 2 | -0.024592 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0239673 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0236891 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0236594 |
| MGAT4C | MGAT4 family, member C | -0.0234727 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0234378 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0229046 |
| ADIPOR2 | adiponectin receptor 2 | -0.0227868 |
| RPS16 | ribosomal protein S16 | -0.0226584 |
| RPL34 | ribosomal protein L34 | -0.0223 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0221898 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0218225 |
| H1-0 | H1.0 linker histone | -0.0218127 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.021692 |
| DEK | DEK proto-oncogene | -0.0216531 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0213661 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0210487 |
| BSG | basigin (Ok blood group) | -0.0201619 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0200787 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.019906 |
| HELLS | helicase, lymphoid-specific | -0.0198943 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.019752 |
| RACK1 | receptor for activated C kinase 1 | -0.0195008 |
| TUBB | tubulin, beta class I | -0.0194763 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0194646 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0194408 |
| USP34 | ubiquitin specific peptidase 34 | -0.0191803 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0188547 |
| H3-3B | H3.3 histone B | -0.0187142 |
| TMEM123 | transmembrane protein 123 | -0.0186147 |
| IPO7 | importin 7 | -0.0185667 |
| YBX1 | Y box binding protein 1 | -0.0183872 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.018329 |
| CAPNS1 | calpain, small subunit 1 | -0.0182499 |
| RPL28 | ribosomal protein L28 | -0.0182229 |
| RPL9 | ribosomal protein L9 | -0.0179539 |
| YAP1 | Yes-associated protein 1 | -0.0177831 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0177608 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0176269 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0175625 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0174549 |
| CCN2 | cellular communication network factor 2 | -0.0174528 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0173419 |
| RPS15 | ribosomal protein S15 | -0.0171073 |
| LDHB | lactate dehydrogenase B | -0.0169531 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0166814 |
| CDK12 | cyclin-dependent kinase 12 | -0.0165981 |
| TUBA1C | tubulin, alpha 1c | -0.0165542 |
| RTN4 | reticulon 4 | -0.0164982 |
| RPL32 | ribosomal protein L32 | -0.0164611 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0162863 |
| RPS23 | ribosomal protein S23 | -0.0162832 |
| CLDN1 | claudin 1 | -0.0162771 |
| JMJD1C | jumonji domain containing 1C | -0.0161919 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.01612 |
