| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | 0.137031 |
| PRELID2 | PRELI domain containing 2 | 0.0906222 |
| GSE1 | Gse1 coiled-coil protein | 0.0683426 |
| RPL3 | ribosomal protein L3 | 0.0665182 |
| MED13L | mediator complex subunit 13-like | 0.0624983 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0619783 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0553073 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0528434 |
| VEGFA | vascular endothelial growth factor A | 0.0514412 |
| NFIB | nuclear factor I/B | 0.048267 |
| SMYD3 | SET and MYND domain containing 3 | 0.0478068 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0477358 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.047552 |
| H1-4 | H1.4 linker histone, cluster member | 0.0446702 |
| FNIP1 | folliculin interacting protein 1 | 0.0444096 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0437822 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0413052 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0408513 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0400243 |
| CENPF | centromere protein F, 350/400kDa | 0.0396735 |
| MEOX2 | mesenchyme homeobox 2 | 0.0391927 |
| GPC6 | glypican 6 | 0.0387277 |
| PDGFC | platelet derived growth factor C | 0.0385203 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0383448 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0381155 |
| SBF2 | SET binding factor 2 | 0.0371001 |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) | 0.0370844 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0366218 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0365605 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0365161 |
| RAB6A | RAB6A, member RAS oncogene family | 0.036339 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0358164 |
| ZNF292 | zinc finger protein 292 | 0.0357451 |
| SPPL3 | signal peptide peptidase like 3 | 0.035698 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0349911 |
| ZNF608 | zinc finger protein 608 | 0.0341149 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0339075 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.033826 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0333158 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.033172 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0329187 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0328296 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 0.0327021 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0325069 |
| ECT2 | epithelial cell transforming 2 | 0.0324409 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0321115 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0316263 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.031062 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0307714 |
| MYEF2 | myelin expression factor 2 | 0.0307621 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0307464 |
| PCM1 | pericentriolar material 1 | 0.0306661 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0305762 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0305753 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0304636 |
| TMSB4X | thymosin beta 4, X-linked | 0.0301291 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0297581 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0297157 |
| NKTR | natural killer cell triggering receptor | 0.0295155 |
| SECISBP2L | SECIS binding protein 2-like | 0.0289106 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0288377 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0286539 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0281325 |
| PTMA | prothymosin, alpha | 0.0280856 |
| UST | uronyl-2-sulfotransferase | 0.0280198 |
| TPI1 | triosephosphate isomerase 1 | 0.0279 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0278319 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0278186 |
| FAM168A | family with sequence similarity 168, member A | 0.026918 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0267102 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.026704 |
| YEATS2 | YEATS domain containing 2 | 0.0263082 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0263079 |
| HOXA3 | homeobox A3 | 0.0261433 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0260073 |
| MIS18BP1 | MIS18 binding protein 1 | 0.025986 |
| ZNF516 | zinc finger protein 516 | 0.0258843 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0257734 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | 0.0256254 |
| SMAD4 | SMAD family member 4 | 0.0253971 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0253658 |
| RANBP2 | RAN binding protein 2 | 0.0249788 |
| ITGAV | integrin, alpha V | 0.0249595 |
| RPS19 | ribosomal protein S19 | 0.024948 |
| SEPTIN7 | septin 7 | 0.0246597 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0246317 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0245719 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0245612 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0244008 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0243784 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0243647 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0242185 |
| BBX | bobby sox homolog (Drosophila) | 0.0242167 |
| CEP250 | centrosomal protein 250kDa | 0.0240578 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0240397 |
| OGA | O-GlcNAcase | 0.0239186 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.0238842 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0238586 |
| CDC73 | cell division cycle 73 | 0.023606 |
| CDK19 | cyclin-dependent kinase 19 | 0.0234603 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.185351 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.156353 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113186 |
| PEG10 | paternally expressed 10 | -0.0849518 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0810316 |
| LDHA | lactate dehydrogenase A | -0.0753661 |
| RPLP1 | ribosomal protein, large, P1 | -0.0690687 |
| AFF4 | AF4/FMR2 family, member 4 | -0.068895 |
| IER3 | immediate early response 3 | -0.0639817 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0598186 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0582994 |
| MAP1B | microtubule-associated protein 1B | -0.0564854 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0545966 |
| CANX | calnexin | -0.0518561 |
| HMGA2 | high mobility group AT-hook 2 | -0.0503707 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0503381 |
| TULP4 | tubby like protein 4 | -0.0502333 |
| FTL | ferritin, light polypeptide | -0.0498562 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0497309 |
| MT2A | metallothionein 2A | -0.0472423 |
| FBXO11 | F-box protein 11 | -0.0455406 |
| MTDH | metadherin | -0.0454089 |
| MGP | matrix Gla protein | -0.0453427 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0438524 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0437908 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0436116 |
| RPS8 | ribosomal protein S8 | -0.0428023 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0427902 |
| TMEM41B | transmembrane protein 41B | -0.0427835 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.042726 |
| SEPTIN11 | septin 11 | -0.0422255 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0414288 |
| UBE3C | ubiquitin protein ligase E3C | -0.0412174 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0404443 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0399157 |
| HMGA1 | high mobility group AT-hook 1 | -0.0397351 |
| TBCA | tubulin folding cofactor A | -0.0395523 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0394523 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.039415 |
| RSU1 | Ras suppressor protein 1 | -0.0388914 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0388399 |
| RANBP17 | RAN binding protein 17 | -0.0381869 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0374002 |
| KAZN | kazrin, periplakin interacting protein | -0.0371946 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0371055 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0370895 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0367718 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0358358 |
| NOP58 | NOP58 ribonucleoprotein | -0.0357058 |
| TCF12 | transcription factor 12 | -0.0355394 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0352581 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0352357 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0342403 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0342168 |
| ACTG1 | actin gamma 1 | -0.0337439 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0335298 |
| FUS | FUS RNA binding protein | -0.0335045 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0332653 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0331185 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0326686 |
| KIF5B | kinesin family member 5B | -0.0325344 |
| RPS24 | ribosomal protein S24 | -0.0319984 |
| RPL30 | ribosomal protein L30 | -0.0315897 |
| LATS2 | large tumor suppressor kinase 2 | -0.0315475 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0313748 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0313584 |
| HDLBP | high density lipoprotein binding protein | -0.0312747 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0312206 |
| JMJD1C | jumonji domain containing 1C | -0.0308798 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0307191 |
| E2F3 | E2F transcription factor 3 | -0.0307049 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0304325 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0303651 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0302628 |
| RPS16 | ribosomal protein S16 | -0.0298538 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.029688 |
| RPL38 | ribosomal protein L38 | -0.02961 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0295479 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0295042 |
| RPLP0 | ribosomal protein, large, P0 | -0.0288489 |
| RPL8 | ribosomal protein L8 | -0.0285257 |
| RPL35A | ribosomal protein L35a | -0.0285037 |
| CCNI | cyclin I | -0.0284729 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0284472 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0284453 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0281166 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0279897 |
| EGR1 | early growth response 1 | -0.0279431 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0278177 |
| GOLM2 | golgi membrane protein 2 | -0.0275591 |
| CDC37 | cell division cycle 37 | -0.0275507 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0275475 |
| RPS20 | ribosomal protein S20 | -0.027386 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0273302 |
| ANO6 | anoctamin 6 | -0.0273292 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0272612 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0272504 |
| CBFB | core-binding factor, beta subunit | -0.0270722 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.026867 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0268288 |
