| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.392534 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.230549 |
| PLEC | plectin | 0.1617 |
| FLNB | filamin B, beta | 0.152991 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.14448 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.140573 |
| AHNAK | AHNAK nucleoprotein | 0.125454 |
| LAMB3 | laminin, beta 3 | 0.11251 |
| EZR | ezrin | 0.102791 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0961894 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0897814 |
| LMO7 | LIM domain 7 | 0.0889786 |
| VCAN | versican | 0.0852591 |
| PTMA | prothymosin, alpha | 0.0824748 |
| DSPP | dentin sialophosphoprotein | 0.0762084 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0713366 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.070477 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0654196 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0640761 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0632908 |
| NPSR1 | neuropeptide S receptor 1 | 0.0629633 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0623533 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0607824 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0600535 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0585308 |
| PGK1 | phosphoglycerate kinase 1 | 0.0581887 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0555092 |
| KRT18 | keratin 18, type I | 0.0536702 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0529828 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0519728 |
| ACTN4 | actinin, alpha 4 | 0.0516206 |
| GRB10 | growth factor receptor-bound protein 10 | 0.051399 |
| EGFR | epidermal growth factor receptor | 0.0490688 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0490368 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0487519 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0480514 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.047982 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0474282 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0459224 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.045349 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0453164 |
| TMSB10 | thymosin beta 10 | 0.0451094 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0447773 |
| VIM | vimentin | 0.0443682 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0440387 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.042666 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0423978 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0423261 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0416921 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0413566 |
| PRELID2 | PRELI domain containing 2 | 0.0397616 |
| CD2AP | CD2-associated protein | 0.0388354 |
| KRT8 | keratin 8, type II | 0.0386587 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0386376 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0384485 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0382561 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.037966 |
| CAPRIN2 | caprin family member 2 | 0.0373924 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0371372 |
| FAM13A | family with sequence similarity 13, member A | 0.0365072 |
| LAMA4 | laminin, alpha 4 | 0.0364692 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0356175 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0355208 |
| OPTN | optineurin | 0.0337136 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0332226 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0328208 |
| TMSB4X | thymosin beta 4, X-linked | 0.0327917 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0327444 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0327048 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0325446 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0323797 |
| CD9 | CD9 molecule | 0.0321404 |
| SLK | STE20-like kinase | 0.0314457 |
| HMGA2 | high mobility group AT-hook 2 | 0.0314368 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0311422 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0310704 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0303582 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0301795 |
| FAT1 | FAT atypical cadherin 1 | 0.0298718 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0298067 |
| DST | dystonin | 0.0297715 |
| FAM107B | family with sequence similarity 107, member B | 0.029754 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0297085 |
| EMP1 | epithelial membrane protein 1 | 0.0296184 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0294759 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0293466 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0290296 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0288536 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0288117 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0285563 |
| FERMT1 | fermitin family member 1 | 0.0284597 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0276998 |
| OGA | O-GlcNAcase | 0.0272272 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0271175 |
| ITGA6 | integrin, alpha 6 | 0.0270093 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.026969 |
| DIAPH2 | diaphanous-related formin 2 | 0.026795 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0267311 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0266164 |
| MYOF | myoferlin | 0.026086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152765 |
| POTEF | POTE ankyrin domain family, member F | -0.14007 |
| NDRG1 | N-myc downstream regulated 1 | -0.131186 |
| HMGA1 | high mobility group AT-hook 1 | -0.113261 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0917223 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0782998 |
| FOSL1 | FOS-like antigen 1 | -0.0595207 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0467816 |
| RTN4 | reticulon 4 | -0.0439062 |
| EGR1 | early growth response 1 | -0.0407069 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0397899 |
| UBC | ubiquitin C | -0.0377449 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.035985 |
| ANXA2 | annexin A2 | -0.0359168 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0343556 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0330162 |
| DSG2 | desmoglein 2 | -0.032898 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0301472 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0295483 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0292254 |
| FTL | ferritin, light polypeptide | -0.028829 |
| H1-0 | H1.0 linker histone | -0.0283181 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0252809 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0251929 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0248932 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0248638 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.024631 |
| LDHA | lactate dehydrogenase A | -0.0244289 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0238905 |
| RHEB | Ras homolog enriched in brain | -0.0237718 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0235429 |
| VCL | vinculin | -0.0233418 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0232211 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0230537 |
| CDCP1 | CUB domain containing protein 1 | -0.0226549 |
| OSMR | oncostatin M receptor | -0.0223793 |
| TXNRD1 | thioredoxin reductase 1 | -0.0222814 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.022272 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0218736 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0217551 |
| RPLP1 | ribosomal protein, large, P1 | -0.0217228 |
| MORF4L2 | mortality factor 4 like 2 | -0.0216157 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0214378 |
| EFNA5 | ephrin-A5 | -0.0210629 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0207846 |
| RUNX1 | runt-related transcription factor 1 | -0.0207247 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0206898 |
| NUP98 | nucleoporin 98kDa | -0.0203603 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0203299 |
| CRY1 | cryptochrome circadian clock 1 | -0.0202191 |
| CLINT1 | clathrin interactor 1 | -0.0200196 |
| WWC1 | WW and C2 domain containing 1 | -0.0199526 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0198869 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0197506 |
| RPS2 | ribosomal protein S2 | -0.0194107 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0192594 |
| SGMS2 | sphingomyelin synthase 2 | -0.0187941 |
| CAB39 | calcium binding protein 39 | -0.0185326 |
| RHOA | ras homolog family member A | -0.0185325 |
| HPCAL1 | hippocalcin-like 1 | -0.0185083 |
| RPS16 | ribosomal protein S16 | -0.0180963 |
| NOP58 | NOP58 ribonucleoprotein | -0.0177952 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0177696 |
| AGO3 | argonaute RISC catalytic component 3 | -0.01766 |
| IL6ST | interleukin 6 signal transducer | -0.0175651 |
| ZFP36 | ZFP36 ring finger protein | -0.0174056 |
| TGM2 | transglutaminase 2 | -0.0172742 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0170695 |
| MTPN | myotrophin | -0.0167153 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0165363 |
| RPL30 | ribosomal protein L30 | -0.0164721 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.016406 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0163773 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0163717 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0163671 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0162468 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0160725 |
| IPO7 | importin 7 | -0.0160704 |
| FOXO3 | forkhead box O3 | -0.0160288 |
| NABP1 | nucleic acid binding protein 1 | -0.0160195 |
| TUBB4B | tubulin, beta 4B class IVb | -0.015997 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0155711 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0155036 |
| RPL9 | ribosomal protein L9 | -0.0152562 |
| RIN2 | Ras and Rab interactor 2 | -0.0151331 |
| VMP1 | vacuole membrane protein 1 | -0.0150879 |
| SF1 | splicing factor 1 | -0.0149965 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0148549 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0145072 |
| RPL7 | ribosomal protein L7 | -0.0144919 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0143342 |
| RPL28 | ribosomal protein L28 | -0.0140853 |
| TJP1 | tight junction protein 1 | -0.0140486 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0140059 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0139666 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0139281 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0139277 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0138865 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.0138003 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0136682 |
