| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TENM3 | teneurin transmembrane protein 3 | 0.143055 |
| NEBL | nebulette | 0.105705 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0876042 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0792738 |
| FMNL2 | formin-like 2 | 0.0666843 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0556418 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0522454 |
| RAD51B | RAD51 paralog B | 0.051131 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0498782 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0459111 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0429627 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0417202 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0412609 |
| RPL41 | ribosomal protein L41 | 0.0403497 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0387313 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0383913 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.037343 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0362582 |
| EFNA5 | ephrin-A5 | 0.035265 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0331756 |
| RPL4 | ribosomal protein L4 | 0.0322778 |
| RPL3 | ribosomal protein L3 | 0.0316871 |
| DENND1A | DENN/MADD domain containing 1A | 0.0314951 |
| HHIP | hedgehog interacting protein | 0.0312617 |
| FAT1 | FAT atypical cadherin 1 | 0.0310465 |
| MDN1 | MDN1, midasin homolog (yeast) | 0.0303884 |
| XPOT | exportin, tRNA | 0.0298037 |
| DIDO1 | death inducer-obliterator 1 | 0.0288865 |
| WDR43 | WD repeat domain 43 | 0.0281814 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0259953 |
| LRRC1 | leucine rich repeat containing 1 | 0.025594 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0247607 |
| ZFP64 | ZFP64 zinc finger protein | 0.0238664 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0235149 |
| PYGL | phosphorylase, glycogen, liver | 0.0234597 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0233234 |
| NGLY1 | N-glycanase 1 | 0.0228865 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0227738 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0225698 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 0.0222968 |
| ZNF160 | zinc finger protein 160 | 0.0220443 |
| CCNY | cyclin Y | 0.0216002 |
| ACACA | acetyl-CoA carboxylase alpha | 0.0214613 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0213709 |
| ATP11A | ATPase, class VI, type 11A | 0.0208802 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.0204749 |
| TBC1D32 | TBC1 domain family, member 32 | 0.0201682 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.020128 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0196954 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0190407 |
| VEGFC | vascular endothelial growth factor C | 0.0188786 |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit | 0.0184061 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0183022 |
| DST | dystonin | 0.0179524 |
| TMEM117 | transmembrane protein 117 | 0.0178734 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0177065 |
| AFG1L | AFG1 like ATPase | 0.0176731 |
| ZNF84 | zinc finger protein 84 | 0.0173811 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0172985 |
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | 0.0172908 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0171493 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0170456 |
| ZNF121 | zinc finger protein 121 | 0.0169391 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0165744 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.016018 |
| UCK2 | uridine-cytidine kinase 2 | 0.0159228 |
| MTA3 | metastasis associated 1 family, member 3 | 0.0156666 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0155365 |
| SRSF7 | serine/arginine-rich splicing factor 7 | 0.0154358 |
| ZNF12 | zinc finger protein 12 | 0.0154037 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0153608 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0153438 |
| MYBBP1A | MYB binding protein (P160) 1a | 0.0151832 |
| APP | amyloid beta (A4) precursor protein | 0.0151378 |
| TMEM178B | transmembrane protein 178B | 0.0150008 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0149787 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.014677 |
| SMAD2 | SMAD family member 2 | 0.0146002 |
| ATXN2L | ataxin 2-like | 0.0145582 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0144775 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.014442 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0144185 |
| TARDBP | TAR DNA binding protein | 0.0142485 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0142398 |
| AOPEP | aminopeptidase O (putative) | 0.0141829 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | 0.0141616 |
| DCTN1 | dynactin 1 | 0.0141549 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0141534 |
| MANBA | mannosidase, beta A, lysosomal | 0.014059 |
| YEATS2 | YEATS domain containing 2 | 0.013988 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0139876 |
| MKRN3 | makorin ring finger protein 3 | 0.0139624 |
| AGO1 | argonaute RISC catalytic component 1 | 0.0139589 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0137902 |
| MYO19 | myosin XIX | 0.0137218 |
| GLMN | glomulin, FKBP associated protein | 0.0135464 |
| ZNF24 | zinc finger protein 24 | 0.0135367 |
| TXNL1 | thioredoxin-like 1 | 0.0134819 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.0134425 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0134425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.311951 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.118735 |
| RPS6 | ribosomal protein S6 | -0.102128 |
| COL5A2 | collagen, type V, alpha 2 | -0.0971232 |
| JMJD1C | jumonji domain containing 1C | -0.0922971 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0771016 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.076343 |
| VCL | vinculin | -0.0730838 |
| PTMA | prothymosin, alpha | -0.0710801 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0709101 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0620697 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0614327 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0606871 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0589252 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0570416 |
| ACTG1 | actin gamma 1 | -0.0542991 |
| RPLP1 | ribosomal protein, large, P1 | -0.0539903 |
| GNAS | GNAS complex locus | -0.0529413 |
| RPL11 | ribosomal protein L11 | -0.0528766 |
| RPS2 | ribosomal protein S2 | -0.0520618 |
| RPL28 | ribosomal protein L28 | -0.0516518 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0490212 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0489769 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0486438 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0481186 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0477218 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.047645 |
| EGR1 | early growth response 1 | -0.0473876 |
| FBXO11 | F-box protein 11 | -0.0472285 |
| RTN4 | reticulon 4 | -0.0469457 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0469204 |
| SEPTIN7 | septin 7 | -0.0465848 |
| NBEAL1 | neurobeachin-like 1 | -0.0462194 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0462194 |
| CCDC88A | coiled-coil domain containing 88A | -0.0461966 |
| CENPF | centromere protein F, 350/400kDa | -0.0460998 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0454698 |
| SETD5 | SET domain containing 5 | -0.0453005 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0446803 |
| BRD2 | bromodomain containing 2 | -0.0439665 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.043228 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0430401 |
| B2M | beta-2-microglobulin | -0.042935 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0423467 |
| PCM1 | pericentriolar material 1 | -0.0416618 |
| RPS21 | ribosomal protein S21 | -0.0412116 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0410685 |
| SYAP1 | synapse associated protein 1 | -0.0405257 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0402108 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0396577 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0395911 |
| GOLGA4 | golgin A4 | -0.0394451 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0389951 |
| PCNX4 | pecanex 4 | -0.0385907 |
| RPS8 | ribosomal protein S8 | -0.0382712 |
| RPL7 | ribosomal protein L7 | -0.0379179 |
| TMSB10 | thymosin beta 10 | -0.0376682 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0371717 |
| FTL | ferritin, light polypeptide | -0.0368868 |
| MKI67 | marker of proliferation Ki-67 | -0.036454 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0364113 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0361408 |
| HMGA1 | high mobility group AT-hook 1 | -0.0359696 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0358508 |
| OGA | O-GlcNAcase | -0.0358408 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0356813 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0356492 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0355311 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0354339 |
| RPL32 | ribosomal protein L32 | -0.0352998 |
| HELZ | helicase with zinc finger | -0.0350646 |
| RPS15 | ribosomal protein S15 | -0.0349586 |
| VMP1 | vacuole membrane protein 1 | -0.0347495 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0347446 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0347116 |
| CADM2 | cell adhesion molecule 2 | -0.0346991 |
| PDE8A | phosphodiesterase 8A | -0.034196 |
| LDHA | lactate dehydrogenase A | -0.0337166 |
| SNX3 | sorting nexin 3 | -0.033657 |
| CABIN1 | calcineurin binding protein 1 | -0.0333979 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0332875 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0332502 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0332472 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0331909 |
| RPL23 | ribosomal protein L23 | -0.0331473 |
| XPO1 | exportin 1 | -0.0330829 |
| CEP350 | centrosomal protein 350kDa | -0.0328989 |
| RPS25 | ribosomal protein S25 | -0.0328637 |
| RPS24 | ribosomal protein S24 | -0.0326535 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0326483 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0325117 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0324365 |
| RPS5 | ribosomal protein S5 | -0.0323555 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0323514 |
| MYO9A | myosin IXA | -0.0322846 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0322077 |
| TAOK1 | TAO kinase 1 | -0.0321902 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0321276 |
| RBM39 | RNA binding motif protein 39 | -0.0321233 |
| GLG1 | golgi glycoprotein 1 | -0.0320609 |
