| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0642692 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0574089 |
| TPR | translocated promoter region, nuclear basket protein | 0.0554737 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.055437 |
| RPL3 | ribosomal protein L3 | 0.0549935 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0404788 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0383091 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0382576 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0374557 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0364971 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0327942 |
| PLEC | plectin | 0.0323833 |
| NUP58 | nucleoporin 58 | 0.0315419 |
| MKRN1 | makorin ring finger protein 1 | 0.0310729 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0309945 |
| CALR | calreticulin | 0.0308701 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0306914 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0297449 |
| COPA | coatomer protein complex, subunit alpha | 0.0295356 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0290539 |
| PKM | pyruvate kinase, muscle | 0.0281429 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0279832 |
| CABIN1 | calcineurin binding protein 1 | 0.0278977 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0278553 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0277711 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0275642 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0274601 |
| FBXO7 | F-box protein 7 | 0.0271953 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0269557 |
| MSN | moesin | 0.0262106 |
| VGF | VGF nerve growth factor inducible | 0.0259236 |
| CD109 | CD109 molecule | 0.0254332 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0252386 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | 0.0244583 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0243219 |
| CEP250 | centrosomal protein 250kDa | 0.0238968 |
| AFDN | afadin, adherens junction formation factor | 0.0237779 |
| HDGF | hepatoma-derived growth factor | 0.0233141 |
| STXBP1 | syntaxin binding protein 1 | 0.0229453 |
| CTTNBP2 | cortactin binding protein 2 | 0.0229387 |
| ANKRD36 | ankyrin repeat domain 36 | 0.022167 |
| SETBP1 | SET binding protein 1 | 0.02211 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0215979 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0214131 |
| RBM26 | RNA binding motif protein 26 | 0.0211392 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0210138 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.0207872 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0207244 |
| SET | SET nuclear proto-oncogene | 0.0206934 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0205981 |
| STRIP2 | striatin interacting protein 2 | 0.0205924 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0204473 |
| RNF145 | ring finger protein 145 | 0.0201388 |
| HMG20B | high mobility group 20B | 0.0201356 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.019805 |
| SETD5 | SET domain containing 5 | 0.0197614 |
| TMEM255B | transmembrane protein 255B | 0.0197429 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0188297 |
| DST | dystonin | 0.0186418 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0184707 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0183489 |
| INSIG2 | insulin induced gene 2 | 0.0182125 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0181442 |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.018091 |
| SRRT | serrate, RNA effector molecule | 0.0180007 |
| SFPQ | splicing factor proline/glutamine-rich | 0.01783 |
| ZYX | zyxin | 0.0178292 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0176882 |
| NOM1 | nucleolar protein with MIF4G domain 1 | 0.0175722 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0174559 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.0174321 |
| ADM | adrenomedullin | 0.017374 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0173294 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0171157 |
| MRTFA | myocardin related transcription factor A | 0.0170257 |
| PNN | pinin, desmosome associated protein | 0.0167272 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0164299 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0163294 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0161989 |
| SEPTIN9 | septin 9 | 0.0161981 |
| TPM3 | tropomyosin 3 | 0.0161292 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0161249 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0161237 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0160913 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0159898 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0158532 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.0158247 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0157382 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0157053 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0154381 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0152072 |
| XPO1 | exportin 1 | 0.0151511 |
| IER2 | immediate early response 2 | 0.0149732 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0149338 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0149201 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0148668 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0146985 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0146537 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0146265 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0146004 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.444355 |
| FN1 | fibronectin 1 | -0.289349 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.182667 |
| GPC6 | glypican 6 | -0.182498 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.143781 |
| VIM | vimentin | -0.140956 |
| FMN1 | formin 1 | -0.109977 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108066 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.10248 |
| TNNC1 | troponin C type 1 (slow) | -0.0965601 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0804849 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0802955 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0778044 |
| TAGLN2 | transgelin 2 | -0.0630272 |
| IER3 | immediate early response 3 | -0.062138 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0594467 |
| NLGN1 | neuroligin 1 | -0.0589496 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0555273 |
| TMSB10 | thymosin beta 10 | -0.0512375 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0507762 |
| RAB7A | RAB7A, member RAS oncogene family | -0.05059 |
| S100A6 | S100 calcium binding protein A6 | -0.0505596 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0505286 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0479293 |
| ANXA2 | annexin A2 | -0.0473274 |
| OSMR | oncostatin M receptor | -0.0465189 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0460952 |
| FRMD4A | FERM domain containing 4A | -0.0459514 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0452779 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0447266 |
| NPR2 | natriuretic peptide receptor 2 | -0.044656 |
| RTN4 | reticulon 4 | -0.0443411 |
| MACROD2 | MACRO domain containing 2 | -0.0441539 |
| RPLP1 | ribosomal protein, large, P1 | -0.0441522 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.044044 |
| A2M | alpha-2-macroglobulin | -0.0435564 |
| HLA-B | major histocompatibility complex, class I, B | -0.0434106 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0427951 |
| VCL | vinculin | -0.0419773 |
| ENO1 | enolase 1, (alpha) | -0.0418756 |
| EGR1 | early growth response 1 | -0.0395282 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0394618 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0381742 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.036937 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.036286 |
| MT2A | metallothionein 2A | -0.0361844 |
| ATF6 | activating transcription factor 6 | -0.0355973 |
| RHEB | Ras homolog enriched in brain | -0.0354715 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0344166 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0343298 |
| COG5 | component of oligomeric golgi complex 5 | -0.0338486 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0336605 |
| FUS | FUS RNA binding protein | -0.0335171 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0330996 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0327257 |
| ACTG1 | actin gamma 1 | -0.0324768 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0321429 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0317726 |
| NDRG1 | N-myc downstream regulated 1 | -0.031687 |
| PTCHD4 | patched domain containing 4 | -0.0316678 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0316027 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0315577 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0313237 |
| RUNX1 | runt-related transcription factor 1 | -0.0312779 |
| CDK14 | cyclin-dependent kinase 14 | -0.0307375 |
| TMEM263 | transmembrane protein 263 | -0.0302571 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0298672 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0298116 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0296715 |
| CANX | calnexin | -0.0296615 |
| LDHA | lactate dehydrogenase A | -0.0285012 |
| NAV3 | neuron navigator 3 | -0.0284469 |
| ZNF292 | zinc finger protein 292 | -0.0282187 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0281857 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0280205 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0276245 |
| RPL35A | ribosomal protein L35a | -0.0275283 |
| HMCN1 | hemicentin 1 | -0.0272665 |
| GDF15 | growth differentiation factor 15 | -0.0270461 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0267685 |
| OXR1 | oxidation resistance 1 | -0.0265358 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.026292 |
| HBP1 | HMG-box transcription factor 1 | -0.0262017 |
| CTSD | cathepsin D | -0.0258569 |
| GTF2B | general transcription factor IIB | -0.0254253 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0253508 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0252905 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0252755 |
| RLF | rearranged L-myc fusion | -0.0252259 |
| MTPN | myotrophin | -0.0252199 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.0251384 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0251055 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0248606 |
| FTL | ferritin, light polypeptide | -0.0247856 |
| TMEM123 | transmembrane protein 123 | -0.0247588 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0245048 |
| EHBP1 | EH domain binding protein 1 | -0.0244228 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0242521 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0241996 |
| PDE10A | phosphodiesterase 10A | -0.0240048 |
