| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.200226 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.17486 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.149522 |
| TMSB4X | thymosin beta 4, X-linked | 0.140705 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.139256 |
| APOL1 | apolipoprotein L, 1 | 0.136856 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.134628 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.122519 |
| ENO1 | enolase 1, (alpha) | 0.113822 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.106114 |
| LAMC2 | laminin, gamma 2 | 0.101237 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0968152 |
| PTMA | prothymosin, alpha | 0.0960176 |
| LAMB3 | laminin, beta 3 | 0.0938753 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0883234 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0872432 |
| APP | amyloid beta (A4) precursor protein | 0.0850669 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0833814 |
| EZR | ezrin | 0.0832472 |
| AHNAK | AHNAK nucleoprotein | 0.0824629 |
| SMAD3 | SMAD family member 3 | 0.0808382 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0796029 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0773785 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0753652 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0749789 |
| B2M | beta-2-microglobulin | 0.072893 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0728453 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.072565 |
| MMP7 | matrix metallopeptidase 7 | 0.070451 |
| PGK1 | phosphoglycerate kinase 1 | 0.0688661 |
| FAM13A | family with sequence similarity 13, member A | 0.0685232 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0678326 |
| DST | dystonin | 0.0676667 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0672871 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0668957 |
| EFNA5 | ephrin-A5 | 0.0663704 |
| PKM | pyruvate kinase, muscle | 0.0655697 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0655638 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0646331 |
| CP | ceruloplasmin (ferroxidase) | 0.0639995 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0624308 |
| RAD51B | RAD51 paralog B | 0.0595003 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0587728 |
| CCNY | cyclin Y | 0.0580274 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0563205 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0561181 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0552323 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0546218 |
| GRB10 | growth factor receptor-bound protein 10 | 0.054437 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.054159 |
| FLNB | filamin B, beta | 0.0541038 |
| CANX | calnexin | 0.0535279 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0521285 |
| DSPP | dentin sialophosphoprotein | 0.0518683 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0508608 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0507327 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.05027 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0500861 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0498854 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0498195 |
| MYOF | myoferlin | 0.0495001 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0492951 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0491285 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0490636 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0485255 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0485113 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0481624 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0478259 |
| ITGA6 | integrin, alpha 6 | 0.0468401 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0465601 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0465111 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0462696 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0462608 |
| CALR | calreticulin | 0.0462182 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0461364 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0459081 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0459017 |
| MT2A | metallothionein 2A | 0.0456853 |
| MCL1 | myeloid cell leukemia 1 | 0.0455219 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0452774 |
| KRT19 | keratin 19, type I | 0.0440421 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.043759 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0437507 |
| LAMA4 | laminin, alpha 4 | 0.0431622 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.042586 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0421444 |
| PRELID2 | PRELI domain containing 2 | 0.0416906 |
| HPCAL1 | hippocalcin-like 1 | 0.0413053 |
| TPM3 | tropomyosin 3 | 0.041228 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0404046 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0395305 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0390083 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0383505 |
| VCL | vinculin | 0.0381357 |
| PLAT | plasminogen activator, tissue | 0.0379952 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0375144 |
| RPS3 | ribosomal protein S3 | 0.0374177 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0371401 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0363222 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0362818 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165247 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0713993 |
| HMGA1 | high mobility group AT-hook 1 | -0.0681049 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0354128 |
| NDRG1 | N-myc downstream regulated 1 | -0.0345781 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0332492 |
| CLDN4 | claudin 4 | -0.03271 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0322752 |
| EGR1 | early growth response 1 | -0.0312032 |
| POTEF | POTE ankyrin domain family, member F | -0.0310221 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0305555 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0270144 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0237491 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0235079 |
| JUP | junction plakoglobin | -0.0229916 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0219219 |
| AGRN | agrin | -0.021583 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0201606 |
| LAMA5 | laminin, alpha 5 | -0.0200326 |
| FTL | ferritin, light polypeptide | -0.0186088 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0185834 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0180283 |
| ZFP36 | ZFP36 ring finger protein | -0.0179258 |
| BRD2 | bromodomain containing 2 | -0.0157631 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0152183 |
| TMSB10 | thymosin beta 10 | -0.015048 |
| CCNL1 | cyclin L1 | -0.0139084 |
| RTN4 | reticulon 4 | -0.0136387 |
| RNF11 | ring finger protein 11 | -0.0130906 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0130561 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0125625 |
| MUC4 | mucin 4, cell surface associated | -0.0124071 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0123314 |
| MYADM | myeloid-associated differentiation marker | -0.01225 |
| PCNX1 | pecanex 1 | -0.0121601 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0121301 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0121048 |
| CD68 | CD68 molecule | -0.0117072 |
| DHFR | dihydrofolate reductase | -0.0114224 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0111348 |
| TAPBP | TAP binding protein (tapasin) | -0.0109391 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0108876 |
| GUK1 | guanylate kinase 1 | -0.0107149 |
| CTSD | cathepsin D | -0.0107097 |
| CLDN7 | claudin 7 | -0.0106112 |
| SPAG9 | sperm associated antigen 9 | -0.0103723 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0103232 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0102626 |
| EMP1 | epithelial membrane protein 1 | -0.0102141 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0101278 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.00990893 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.00969443 |
| C3ORF52 | chromosome 3 open reading frame 52 | -0.00966411 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.00960296 |
| YBX1 | Y box binding protein 1 | -0.00959752 |
| TMEM165 | transmembrane protein 165 | -0.00943611 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0093427 |
| TMEM62 | transmembrane protein 62 | -0.00930737 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.00930279 |
| MYO6 | myosin VI | -0.00898667 |
| RAB22A | RAB22A, member RAS oncogene family | -0.00893054 |
| MYO5B | myosin VB | -0.00892638 |
| CRABP2 | cellular retinoic acid binding protein 2 | -0.00889303 |
| PER2 | period circadian clock 2 | -0.00886167 |
| PRSS8 | protease, serine, 8 | -0.0088519 |
| SGMS2 | sphingomyelin synthase 2 | -0.00868453 |
| PFN1 | profilin 1 | -0.00861326 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.00855249 |
| TOB1 | transducer of ERBB2, 1 | -0.00854252 |
| TRIB1 | tribbles pseudokinase 1 | -0.00854175 |
| TSC22D4 | TSC22 domain family, member 4 | -0.0084974 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00841456 |
| SF1 | splicing factor 1 | -0.00835703 |
| ACTG1 | actin gamma 1 | -0.00832642 |
| MED26 | mediator complex subunit 26 | -0.0082836 |
| PLAG1 | pleiomorphic adenoma gene 1 | -0.00826156 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.00826029 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.00824414 |
| BSG | basigin (Ok blood group) | -0.00821104 |
| CCNK | cyclin K | -0.00814499 |
| RPL21 | ribosomal protein L21 | -0.00813998 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.00812583 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.00812097 |
| ABI1 | abl-interactor 1 | -0.00811613 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.00801131 |
| DAD1 | defender against cell death 1 | -0.0080105 |
| PER1 | period circadian clock 1 | -0.00799855 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.00792322 |
| RNASEH2A | ribonuclease H2, subunit A | -0.00788302 |
| RPS23 | ribosomal protein S23 | -0.00782333 |
| DEPP1 | DEPP autophagy regulator 1 | -0.00781688 |
| APH1A | APH1A gamma secretase subunit | -0.00779011 |
| RBM27 | RNA binding motif protein 27 | -0.00778745 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.00776765 |
| RC3H1 | ring finger and CCCH-type domains 1 | -0.00774031 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.00769994 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00767326 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.00766222 |
| OCLN | occludin | -0.00763588 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | -0.00762652 |
