| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.0724452 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0714599 |
| HELZ | helicase with zinc finger | 0.0648648 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0610207 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0546594 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0491269 |
| LPIN1 | lipin 1 | 0.0471723 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0456648 |
| ZNF292 | zinc finger protein 292 | 0.0444928 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0422871 |
| OGA | O-GlcNAcase | 0.0397796 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0393354 |
| PKM | pyruvate kinase, muscle | 0.0388742 |
| RNF145 | ring finger protein 145 | 0.0381636 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0365694 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0355906 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0343292 |
| HMGB2 | high mobility group box 2 | 0.0336975 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0330542 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0329743 |
| SPAG9 | sperm associated antigen 9 | 0.0329671 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0329393 |
| WDR45B | WD repeat domain 45B | 0.0328247 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0324721 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0310371 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0308299 |
| XPO1 | exportin 1 | 0.0295456 |
| DST | dystonin | 0.0291247 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0286657 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0286046 |
| MED13L | mediator complex subunit 13-like | 0.0285912 |
| LMNA | lamin A/C | 0.0284636 |
| NCKAP1 | NCK-associated protein 1 | 0.0282453 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.028206 |
| NBAS | neuroblastoma amplified sequence | 0.0277882 |
| ANXA2 | annexin A2 | 0.0275655 |
| SEPTIN9 | septin 9 | 0.027413 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0267648 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.026437 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0263635 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0262304 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0260034 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0259869 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0256279 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.025446 |
| SETD5 | SET domain containing 5 | 0.0253128 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.0250987 |
| SUCO | SUN domain containing ossification factor | 0.0247043 |
| CDC27 | cell division cycle 27 | 0.0245376 |
| NUP58 | nucleoporin 58 | 0.0241888 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0239807 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0238123 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0238012 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0234546 |
| RIOK3 | RIO kinase 3 | 0.023288 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0231197 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0229451 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0229331 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0228085 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0224017 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0223827 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0222854 |
| WDR43 | WD repeat domain 43 | 0.0222611 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0220566 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 0.0218838 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0217719 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0217612 |
| CASC3 | cancer susceptibility candidate 3 | 0.0215522 |
| SRP54 | signal recognition particle 54kDa | 0.0215237 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0215095 |
| UBQLN1 | ubiquilin 1 | 0.0214737 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0209382 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0209352 |
| RPL41 | ribosomal protein L41 | 0.0209214 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0204061 |
| ENAH | enabled homolog (Drosophila) | 0.0202835 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0202211 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.020219 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0201059 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0200058 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0198701 |
| USP3 | ubiquitin specific peptidase 3 | 0.0196321 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0195587 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0195455 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0194532 |
| COL3A1 | collagen, type III, alpha 1 | 0.0193396 |
| TRIM37 | tripartite motif containing 37 | 0.0191632 |
| GOLGA4 | golgin A4 | 0.0191226 |
| RBM33 | RNA binding motif protein 33 | 0.0188017 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0186811 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.018639 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.018637 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.0186106 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0184795 |
| FNBP1 | formin binding protein 1 | 0.0184397 |
| ZNF148 | zinc finger protein 148 | 0.0182743 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0182547 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0182134 |
| ECT2 | epithelial cell transforming 2 | 0.0181715 |
| ABI2 | abl-interactor 2 | 0.0180827 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.311368 |
| NRG1 | neuregulin 1 | -0.20166 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.196317 |
| LSAMP | limbic system-associated membrane protein | -0.188388 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123429 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.106519 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0940747 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0931093 |
| SYT1 | synaptotagmin I | -0.0919933 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0883772 |
| FMN1 | formin 1 | -0.0843219 |
| VCL | vinculin | -0.0803262 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.077914 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0717841 |
| CADM2 | cell adhesion molecule 2 | -0.067188 |
| BPTF | bromodomain PHD finger transcription factor | -0.0643208 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0641028 |
| NREP | neuronal regeneration related protein | -0.0626981 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0625002 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0587742 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0587577 |
| ZNF804A | zinc finger protein 804A | -0.0572524 |
| CUX1 | cut-like homeobox 1 | -0.0559982 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0555046 |
| ACTG1 | actin gamma 1 | -0.0540965 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0537932 |
| PRKCA | protein kinase C, alpha | -0.0522087 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0513521 |
| RPL23 | ribosomal protein L23 | -0.0510924 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0502981 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0500572 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0498168 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0495575 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0490603 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0490295 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0488112 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.047255 |
| KLHL13 | kelch-like family member 13 | -0.0470038 |
| DPH6 | diphthamine biosynthesis 6 | -0.0461179 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0455049 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0444479 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0440626 |
| HIP1 | huntingtin interacting protein 1 | -0.0434315 |
| COL1A1 | collagen, type I, alpha 1 | -0.0431239 |
| SMYD3 | SET and MYND domain containing 3 | -0.0430834 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.042979 |
| CRH | corticotropin releasing hormone | -0.0401749 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0401141 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0400998 |
| RPS6 | ribosomal protein S6 | -0.0399958 |
| RNF213 | ring finger protein 213 | -0.0398235 |
| PLAT | plasminogen activator, tissue | -0.0396432 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0392143 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0390619 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.038959 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0385326 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0383287 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0381806 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0374424 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0366962 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0362709 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0361571 |
| PDZRN3 | PDZ domain containing ring finger 3 | -0.0354564 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0350504 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0350056 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0346849 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0342985 |
| RPLP1 | ribosomal protein, large, P1 | -0.0341943 |
| EFNA5 | ephrin-A5 | -0.0332175 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0332094 |
| DNM3 | dynamin 3 | -0.0330579 |
| NBEA | neurobeachin | -0.0328235 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0323312 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0322607 |
| ATRNL1 | attractin-like 1 | -0.032247 |
| RAD51B | RAD51 paralog B | -0.0319854 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0319474 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0318061 |
| EGR1 | early growth response 1 | -0.0316399 |
| RPL31 | ribosomal protein L31 | -0.0314564 |
| NRP1 | neuropilin 1 | -0.0306734 |
| GSE1 | Gse1 coiled-coil protein | -0.0304452 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0304336 |
| SP100 | SP100 nuclear antigen | -0.0304015 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0298698 |
| TRIB2 | tribbles pseudokinase 2 | -0.0295596 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0289408 |
| TCF12 | transcription factor 12 | -0.0289073 |
| ZNF609 | zinc finger protein 609 | -0.0288348 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0284986 |
| TPM1 | tropomyosin 1 (alpha) | -0.0284709 |
| TENM4 | teneurin transmembrane protein 4 | -0.0284563 |
| RPL35A | ribosomal protein L35a | -0.0284469 |
| MYO9A | myosin IXA | -0.0283168 |
| MSI2 | musashi RNA-binding protein 2 | -0.0282897 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0282543 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0281898 |
| FHIT | fragile histidine triad | -0.0281376 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0281043 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0277928 |
