| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.120688 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0999478 |
| PHF3 | PHD finger protein 3 | 0.0963576 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0846842 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0802431 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0771606 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0753393 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0740986 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0695218 |
| DSPP | dentin sialophosphoprotein | 0.0694077 |
| LYZ | lysozyme | 0.069011 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.067331 |
| APOL1 | apolipoprotein L, 1 | 0.0645458 |
| ASPH | aspartate beta-hydroxylase | 0.0644731 |
| CANX | calnexin | 0.0635953 |
| PTMA | prothymosin, alpha | 0.0631851 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0622743 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0611346 |
| ABHD2 | abhydrolase domain containing 2 | 0.0567394 |
| PGK1 | phosphoglycerate kinase 1 | 0.0556696 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0541405 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0539951 |
| AHNAK | AHNAK nucleoprotein | 0.0538771 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0537493 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.05365 |
| PRKCA | protein kinase C, alpha | 0.0536175 |
| PRELID2 | PRELI domain containing 2 | 0.0532956 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0525934 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0524623 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0520612 |
| KIF16B | kinesin family member 16B | 0.0520387 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0520007 |
| FAT1 | FAT atypical cadherin 1 | 0.0513095 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0504874 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0504873 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0499514 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0497036 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0495546 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0485449 |
| NPSR1 | neuropeptide S receptor 1 | 0.0470669 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0464594 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0459125 |
| ENO1 | enolase 1, (alpha) | 0.0454221 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0453048 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0451031 |
| UBAC2 | UBA domain containing 2 | 0.0447986 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0445895 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0439746 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0421661 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0408298 |
| CALR | calreticulin | 0.0401537 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0396596 |
| ERCC5 | excision repair cross-complementation group 5 | 0.0394841 |
| MLPH | melanophilin | 0.039391 |
| AHI1 | Abelson helper integration site 1 | 0.039201 |
| RAD51B | RAD51 paralog B | 0.0391409 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0389993 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.038526 |
| MSI2 | musashi RNA-binding protein 2 | 0.0378429 |
| APP | amyloid beta (A4) precursor protein | 0.0376574 |
| RNF149 | ring finger protein 149 | 0.0370506 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0369574 |
| TMSB4X | thymosin beta 4, X-linked | 0.0368443 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0366564 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0362029 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.0361069 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0358799 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0357624 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0355352 |
| CMIP | c-Maf inducing protein | 0.0353376 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.034981 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0348892 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0348327 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.034659 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0340057 |
| TXNIP | thioredoxin interacting protein | 0.0328711 |
| JMJD1C | jumonji domain containing 1C | 0.0325596 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0324651 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0321222 |
| ZNF638 | zinc finger protein 638 | 0.0318284 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0318232 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0313462 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0310228 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0309623 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0309336 |
| CLTC | clathrin, heavy chain (Hc) | 0.0308758 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0307588 |
| RBM26 | RNA binding motif protein 26 | 0.0303646 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0301484 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0298709 |
| ATXN1 | ataxin 1 | 0.0298524 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.029703 |
| CCDC146 | coiled-coil domain containing 146 | 0.0292945 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0292185 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0291755 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0290583 |
| EPCAM | epithelial cell adhesion molecule | 0.028959 |
| MUC20 | mucin 20, cell surface associated | 0.0287575 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0287202 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0285434 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGR1 | early growth response 1 | -0.165549 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.158163 |
| LMO7 | LIM domain 7 | -0.135897 |
| ANXA2 | annexin A2 | -0.123295 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.109349 |
| MYO1E | myosin IE | -0.102099 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0764775 |
| B2M | beta-2-microglobulin | -0.0695914 |
| LCN2 | lipocalin 2 | -0.0689763 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0668235 |
| MX2 | MX dynamin-like GTPase 2 | -0.0661221 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0620253 |
| CCNL1 | cyclin L1 | -0.0616415 |
| VCL | vinculin | -0.0578481 |
| VMP1 | vacuole membrane protein 1 | -0.0572226 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0545593 |
| TJP1 | tight junction protein 1 | -0.0538043 |
| IRF1 | interferon regulatory factor 1 | -0.0525304 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0520778 |
| CLDN4 | claudin 4 | -0.0490648 |
| FTL | ferritin, light polypeptide | -0.0475785 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.047071 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0469929 |
| PLSCR1 | phospholipid scramblase 1 | -0.0465771 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0453675 |
| POTEF | POTE ankyrin domain family, member F | -0.0450151 |
| RIGI | RNA sensor RIG-I | -0.044599 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.044315 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0420603 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0415905 |
| PERP | PERP, TP53 apoptosis effector | -0.0412029 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0411835 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0411771 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.0404119 |
| RPL35A | ribosomal protein L35a | -0.0401585 |
| STK24 | serine/threonine kinase 24 | -0.0401394 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0392579 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0388087 |
| SP100 | SP100 nuclear antigen | -0.0383395 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0379397 |
| MT2A | metallothionein 2A | -0.0369232 |
| RPLP1 | ribosomal protein, large, P1 | -0.0364128 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.036371 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.036128 |
| TRIB1 | tribbles pseudokinase 1 | -0.033523 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0328651 |
| CST3 | cystatin C | -0.0327549 |
| INTS6 | integrator complex subunit 6 | -0.0324607 |
| AREG | amphiregulin | -0.0322928 |
| TMSB10 | thymosin beta 10 | -0.0320254 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0317194 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0316867 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.031345 |
| HLA-B | major histocompatibility complex, class I, B | -0.0306604 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.030416 |
| ERBIN | erbb2 interacting protein | -0.0302806 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0300296 |
| FOXO3 | forkhead box O3 | -0.0292251 |
| RPL23 | ribosomal protein L23 | -0.0291569 |
| S100A10 | S100 calcium binding protein A10 | -0.0289693 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0289435 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0287539 |
| PMP22 | peripheral myelin protein 22 | -0.02869 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0285461 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0283779 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0280251 |
| TMEM165 | transmembrane protein 165 | -0.0277892 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0277845 |
| RPS6 | ribosomal protein S6 | -0.0271797 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0270093 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.026896 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0268835 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0268405 |
| KIAA1217 | KIAA1217 | -0.0264141 |
| MX1 | MX dynamin-like GTPase 1 | -0.0262917 |
| RPLP2 | ribosomal protein, large, P2 | -0.0262488 |
| BCL2L1 | BCL2-like 1 | -0.0261879 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0254011 |
| YAP1 | Yes-associated protein 1 | -0.0252625 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0251822 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0249531 |
| BPTF | bromodomain PHD finger transcription factor | -0.0245467 |
| TC2N | tandem C2 domains, nuclear | -0.024491 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.024477 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0243926 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0243792 |
| HM13 | histocompatibility (minor) 13 | -0.0243304 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0240935 |
| RPL31 | ribosomal protein L31 | -0.0240377 |
| EFNB2 | ephrin-B2 | -0.0237184 |
| RPS27 | ribosomal protein S27 | -0.0233361 |
| KLF6 | Kruppel-like factor 6 | -0.0231748 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0231669 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0230371 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0229207 |
| MCU | mitochondrial calcium uniporter | -0.022871 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0226389 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.022234 |
| TRIM25 | tripartite motif containing 25 | -0.0221728 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0221083 |
