| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.124317 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.119549 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0680692 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0675444 |
| SMAD3 | SMAD family member 3 | 0.0669136 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0502424 |
| FAM13A | family with sequence similarity 13, member A | 0.0451079 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0449427 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0420838 |
| MSN | moesin | 0.0390464 |
| GLIS3 | GLIS family zinc finger 3 | 0.0374065 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0367802 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.036428 |
| YEATS2 | YEATS domain containing 2 | 0.0363287 |
| ZNF841 | zinc finger protein 841 | 0.0361142 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0361121 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0355387 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0340115 |
| NAV2 | neuron navigator 2 | 0.0332544 |
| EGFR | epidermal growth factor receptor | 0.0320457 |
| ATP13A3 | ATPase type 13A3 | 0.0304626 |
| RPL3 | ribosomal protein L3 | 0.0302872 |
| PRELID2 | PRELI domain containing 2 | 0.0301511 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0298374 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0296293 |
| TPM3 | tropomyosin 3 | 0.0287237 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.028563 |
| MYOF | myoferlin | 0.0276148 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0266272 |
| FLNA | filamin A, alpha | 0.026586 |
| METTL15 | methyltransferase like 15 | 0.0261589 |
| ZNF395 | zinc finger protein 395 | 0.0247685 |
| PLEC | plectin | 0.0247136 |
| COL5A1 | collagen, type V, alpha 1 | 0.0243755 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0241949 |
| STC1 | stanniocalcin 1 | 0.0239481 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0236411 |
| FAM219A | family with sequence similarity 219, member A | 0.0236055 |
| PCBP3 | poly(rC) binding protein 3 | 0.0232936 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0231013 |
| ZNF160 | zinc finger protein 160 | 0.0230456 |
| GOLGB1 | golgin B1 | 0.0226171 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0222906 |
| STK17B | serine/threonine kinase 17b | 0.0219466 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0216711 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0216268 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0212276 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.021017 |
| CLTC | clathrin, heavy chain (Hc) | 0.0210126 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0210037 |
| SET | SET nuclear proto-oncogene | 0.020983 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0209387 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0209246 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.020888 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0206839 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0200237 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0200221 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0197887 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0195718 |
| ZNF292 | zinc finger protein 292 | 0.0194778 |
| ANO6 | anoctamin 6 | 0.019392 |
| PMM2 | phosphomannomutase 2 | 0.0192551 |
| ZNF638 | zinc finger protein 638 | 0.0190303 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0189922 |
| WDR26 | WD repeat domain 26 | 0.0189805 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0187534 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0187224 |
| RNF220 | ring finger protein 220 | 0.0186137 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0183244 |
| ZNF146 | zinc finger protein 146 | 0.0182917 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0181564 |
| CDK19 | cyclin-dependent kinase 19 | 0.0180331 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0177832 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0176703 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0176589 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0176081 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0175538 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0173875 |
| MYO1B | myosin IB | 0.0171297 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0171243 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0171125 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0170873 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0169399 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0168514 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0168454 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.016702 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0166736 |
| FNIP1 | folliculin interacting protein 1 | 0.0166118 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0165326 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0162839 |
| NBEAL1 | neurobeachin-like 1 | 0.0162588 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0162234 |
| SBF2 | SET binding factor 2 | 0.0161555 |
| FLNB | filamin B, beta | 0.0161086 |
| COPA | coatomer protein complex, subunit alpha | 0.0157973 |
| INSIG2 | insulin induced gene 2 | 0.0153641 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0153218 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0150853 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0149472 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0148789 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.406486 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.289875 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.250644 |
| FTL | ferritin, light polypeptide | -0.200183 |
| TMSB10 | thymosin beta 10 | -0.147292 |
| VIM | vimentin | -0.143699 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.125224 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.084627 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0808815 |
| HLA-B | major histocompatibility complex, class I, B | -0.0751498 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0748738 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0729357 |
| B2M | beta-2-microglobulin | -0.0724125 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0618487 |
| PTMA | prothymosin, alpha | -0.0601899 |
| FN1 | fibronectin 1 | -0.059593 |
| RPL35A | ribosomal protein L35a | -0.0568448 |
| RPS6 | ribosomal protein S6 | -0.0566745 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0558428 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0556222 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0555615 |
| RPS8 | ribosomal protein S8 | -0.0518636 |
| RPLP1 | ribosomal protein, large, P1 | -0.046232 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0462209 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0451535 |
| CADM1 | cell adhesion molecule 1 | -0.0444028 |
| CD44 | CD44 molecule (Indian blood group) | -0.0434596 |
| ASPH | aspartate beta-hydroxylase | -0.0410995 |
| TPM4 | tropomyosin 4 | -0.0393689 |
| POTEF | POTE ankyrin domain family, member F | -0.0382971 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.038287 |
| CLMP | CXADR-like membrane protein | -0.0375499 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0374826 |
| RPL28 | ribosomal protein L28 | -0.0373398 |
| EGR1 | early growth response 1 | -0.0373263 |
| GNAS | GNAS complex locus | -0.0364811 |
| HLA-A | major histocompatibility complex, class I, A | -0.036262 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0362453 |
| MT2A | metallothionein 2A | -0.035843 |
| MAP1B | microtubule-associated protein 1B | -0.0346971 |
| RPLP0 | ribosomal protein, large, P0 | -0.0340104 |
| LDHA | lactate dehydrogenase A | -0.0338635 |
| NLGN1 | neuroligin 1 | -0.0335198 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0325786 |
| S100A10 | S100 calcium binding protein A10 | -0.0325687 |
| S100A6 | S100 calcium binding protein A6 | -0.0323757 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0320394 |
| RPS24 | ribosomal protein S24 | -0.0319423 |
| ACTG1 | actin gamma 1 | -0.0317464 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0314015 |
| IGF2 | insulin-like growth factor 2 | -0.0310682 |
| RPL34 | ribosomal protein L34 | -0.0310304 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0306558 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0304966 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0299109 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0297875 |
| NAV3 | neuron navigator 3 | -0.0295296 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0292742 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0285151 |
| RPS25 | ribosomal protein S25 | -0.0277892 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0275808 |
| RPL31 | ribosomal protein L31 | -0.0271088 |
| CANX | calnexin | -0.0269756 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.026734 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0263183 |
| IER3 | immediate early response 3 | -0.026107 |
| PRSS23 | protease, serine, 23 | -0.0259796 |
| CCND1 | cyclin D1 | -0.025792 |
| CALD1 | caldesmon 1 | -0.0254745 |
| ENO1 | enolase 1, (alpha) | -0.0243087 |
| S100A9 | S100 calcium binding protein A9 | -0.0242799 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0241797 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0240588 |
| RPL9 | ribosomal protein L9 | -0.0240398 |
| RPS13 | ribosomal protein S13 | -0.0239082 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0238959 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.0235552 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0235238 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0235029 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0234847 |
| HMGA1 | high mobility group AT-hook 1 | -0.0234436 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0234428 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0232023 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0231491 |
| RPLP2 | ribosomal protein, large, P2 | -0.0230802 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0228684 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0226862 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0225759 |
| ANXA2 | annexin A2 | -0.0225005 |
| RPS23 | ribosomal protein S23 | -0.0222547 |
| TENM3 | teneurin transmembrane protein 3 | -0.0220589 |
| UBC | ubiquitin C | -0.0218363 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0216883 |
| ZNF804A | zinc finger protein 804A | -0.0216149 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0214965 |
| RPL12 | ribosomal protein L12 | -0.0214367 |
| RPS16 | ribosomal protein S16 | -0.0214043 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0213629 |
| HLA-C | major histocompatibility complex, class I, C | -0.0213441 |
| HIP1 | huntingtin interacting protein 1 | -0.0213087 |
