| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.160724 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0868776 |
| RPL3 | ribosomal protein L3 | 0.0665962 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0664356 |
| DSPP | dentin sialophosphoprotein | 0.0576732 |
| VEGFA | vascular endothelial growth factor A | 0.0548305 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0512563 |
| ENO1 | enolase 1, (alpha) | 0.0512538 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0506143 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0503199 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0498023 |
| YEATS2 | YEATS domain containing 2 | 0.0461507 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0457339 |
| NUP58 | nucleoporin 58 | 0.0440117 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0419993 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0412699 |
| TMF1 | TATA element modulatory factor 1 | 0.0406195 |
| NDRG1 | N-myc downstream regulated 1 | 0.039596 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0391427 |
| PCM1 | pericentriolar material 1 | 0.0389866 |
| PCBP2 | poly(rC) binding protein 2 | 0.0389166 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0373273 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0360189 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0359333 |
| PKM | pyruvate kinase, muscle | 0.0357808 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0340086 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0336986 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0332124 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0330992 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0329171 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0316637 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0313147 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0308661 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0300381 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0297583 |
| HYOU1 | hypoxia up-regulated 1 | 0.0292354 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0291137 |
| TBC1D22A | TBC1 domain family, member 22A | 0.028494 |
| CDK19 | cyclin-dependent kinase 19 | 0.0281905 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0277158 |
| TPM3 | tropomyosin 3 | 0.0274902 |
| CCNL1 | cyclin L1 | 0.0268227 |
| MKRN1 | makorin ring finger protein 1 | 0.0267201 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0263408 |
| CEP250 | centrosomal protein 250kDa | 0.0260697 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0254918 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0254056 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0252514 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0251661 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0249952 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0249895 |
| HELZ | helicase with zinc finger | 0.0247051 |
| SETD5 | SET domain containing 5 | 0.0246373 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0246297 |
| SH3GL1 | SH3-domain GRB2-like 1 | 0.0239193 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0239179 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0239125 |
| XPOT | exportin, tRNA | 0.023845 |
| INSIG2 | insulin induced gene 2 | 0.0238426 |
| CCNG2 | cyclin G2 | 0.0236962 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0234939 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0230911 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0229937 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.022984 |
| ZNF160 | zinc finger protein 160 | 0.0228644 |
| PGM3 | phosphoglucomutase 3 | 0.0224299 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0224203 |
| RPS3 | ribosomal protein S3 | 0.0220043 |
| ATF4 | activating transcription factor 4 | 0.0218129 |
| CPNE1 | copine I | 0.0218018 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.021688 |
| SEPTIN9 | septin 9 | 0.0212194 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0212023 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0211497 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0211179 |
| ZNF292 | zinc finger protein 292 | 0.0210486 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0209655 |
| DNM2 | dynamin 2 | 0.0208777 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0202506 |
| ATXN1 | ataxin 1 | 0.0202347 |
| GTPBP2 | GTP binding protein 2 | 0.0201128 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0200455 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0199777 |
| RUNX1 | runt-related transcription factor 1 | 0.0197352 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0197249 |
| ADD3 | adducin 3 (gamma) | 0.0196298 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.01961 |
| PLEC | plectin | 0.0193967 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0193196 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0192888 |
| SLK | STE20-like kinase | 0.019036 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0189795 |
| SSRP1 | structure specific recognition protein 1 | 0.0188818 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0188315 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0188237 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0187755 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0187333 |
| NRDC | nardilysin convertase | 0.0186882 |
| FLNB | filamin B, beta | 0.0184636 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0184158 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.370825 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.179497 |
| AHNAK | AHNAK nucleoprotein | -0.148145 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0974402 |
| TXNRD1 | thioredoxin reductase 1 | -0.0888629 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0795098 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0707378 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0652881 |
| ANXA2 | annexin A2 | -0.062186 |
| TMSB10 | thymosin beta 10 | -0.0575053 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0566701 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.056612 |
| HMGA1 | high mobility group AT-hook 1 | -0.0556101 |
| FHIT | fragile histidine triad | -0.0546175 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.051262 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0508087 |
| TENM3 | teneurin transmembrane protein 3 | -0.0506183 |
| RPS24 | ribosomal protein S24 | -0.0505635 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0500915 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.048082 |
| HDLBP | high density lipoprotein binding protein | -0.0477604 |
| LMAN1 | lectin, mannose-binding, 1 | -0.046688 |
| MED13L | mediator complex subunit 13-like | -0.046678 |
| FAT1 | FAT atypical cadherin 1 | -0.0464897 |
| FTL | ferritin, light polypeptide | -0.0460976 |
| FUS | FUS RNA binding protein | -0.0455803 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0447336 |
| SQSTM1 | sequestosome 1 | -0.0441244 |
| RPL27A | ribosomal protein L27a | -0.043379 |
| RRBP1 | ribosome binding protein 1 | -0.0432016 |
| RPLP0 | ribosomal protein, large, P0 | -0.0422367 |
| LDHA | lactate dehydrogenase A | -0.0414629 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.041292 |
| CANX | calnexin | -0.0410759 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0410147 |
| RBM39 | RNA binding motif protein 39 | -0.0408062 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0407285 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0406278 |
| VCL | vinculin | -0.0406231 |
| NF1 | neurofibromin 1 | -0.040622 |
| ARF4 | ADP-ribosylation factor 4 | -0.0397823 |
| TBC1D4 | TBC1 domain family, member 4 | -0.0375241 |
| TMEM263 | transmembrane protein 263 | -0.03692 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0367446 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0359782 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0359635 |
| FRMD5 | FERM domain containing 5 | -0.0357407 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.035333 |
| TCF12 | transcription factor 12 | -0.0348348 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0347256 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0347143 |
| SRP72 | signal recognition particle 72kDa | -0.0344701 |
| CD2AP | CD2-associated protein | -0.0342968 |
| KRT8 | keratin 8, type II | -0.0339829 |
| OGA | O-GlcNAcase | -0.0332646 |
| EGR1 | early growth response 1 | -0.0326711 |
| JMJD1C | jumonji domain containing 1C | -0.0326351 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0322618 |
| SDC4 | syndecan 4 | -0.0322512 |
| MORF4L2 | mortality factor 4 like 2 | -0.0321684 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0321307 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0317964 |
| RPLP1 | ribosomal protein, large, P1 | -0.0317782 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0314358 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.031076 |
| ARF1 | ADP-ribosylation factor 1 | -0.0309809 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0306984 |
| GPHN | gephyrin | -0.0306357 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0301465 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0301345 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0299733 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0295808 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0293875 |
| EZR | ezrin | -0.0292252 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0285145 |
| EXOC6B | exocyst complex component 6B | -0.028473 |
| RPL11 | ribosomal protein L11 | -0.0281677 |
| RAB1A | RAB1A, member RAS oncogene family | -0.028126 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0279804 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -0.0276245 |
| PATJ | PATJ crumbs cell polarity complex component | -0.027572 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0275499 |
| RTN3 | reticulon 3 | -0.0272843 |
| SMYD3 | SET and MYND domain containing 3 | -0.0272492 |
| SEPTIN2 | septin 2 | -0.0270779 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0267603 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0267186 |
| EXOC4 | exocyst complex component 4 | -0.0265246 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0264729 |
| S100A10 | S100 calcium binding protein A10 | -0.0263909 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0262569 |
| RPL35A | ribosomal protein L35a | -0.0258222 |
| PUM2 | pumilio RNA-binding family member 2 | -0.025666 |
| CCND1 | cyclin D1 | -0.0256625 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0255244 |
| RPS21 | ribosomal protein S21 | -0.0253876 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0252797 |
| AK1 | adenylate kinase 1 | -0.025244 |
| RPS8 | ribosomal protein S8 | -0.0246854 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0246439 |
