| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.171215 |
| ATP13A3 | ATPase type 13A3 | 0.0636017 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0612104 |
| PLEC | plectin | 0.0537736 |
| RPL3 | ribosomal protein L3 | 0.0331902 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0318247 |
| FLNA | filamin A, alpha | 0.0280891 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0277203 |
| ARRDC3 | arrestin domain containing 3 | 0.0260536 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0250331 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0249974 |
| SMAD3 | SMAD family member 3 | 0.0247051 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0237252 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0223928 |
| MSN | moesin | 0.0221751 |
| TFG | TRK-fused gene | 0.0214533 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0206572 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0196811 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.018656 |
| PDE8A | phosphodiesterase 8A | 0.0183111 |
| RNF145 | ring finger protein 145 | 0.0178059 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0176856 |
| TPM2 | tropomyosin 2 (beta) | 0.0176637 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0165684 |
| TNS1 | tensin 1 | 0.0163463 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.016036 |
| CUL4B | cullin 4B | 0.0156485 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0154661 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0153725 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0151796 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0150097 |
| FMNL2 | formin-like 2 | 0.0148551 |
| HYOU1 | hypoxia up-regulated 1 | 0.014772 |
| USP3 | ubiquitin specific peptidase 3 | 0.0145611 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0142436 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0141299 |
| ADM | adrenomedullin | 0.0140766 |
| NAV2 | neuron navigator 2 | 0.0136996 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0135546 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0132214 |
| H1-4 | H1.4 linker histone, cluster member | 0.0131706 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0129462 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0128467 |
| FOSL1 | FOS-like antigen 1 | 0.0126539 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0125998 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.012589 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0125448 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0125219 |
| RASA2 | RAS p21 protein activator 2 | 0.0124562 |
| FNBP1L | formin binding protein 1-like | 0.0122224 |
| CCNY | cyclin Y | 0.0120925 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0120372 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0120166 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0119351 |
| RBM39 | RNA binding motif protein 39 | 0.0117817 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0117713 |
| OPTN | optineurin | 0.0117692 |
| NUP58 | nucleoporin 58 | 0.0117614 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0117595 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0116502 |
| OGA | O-GlcNAcase | 0.0115869 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0115339 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.011527 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0113363 |
| FLNB | filamin B, beta | 0.0112993 |
| SPAG9 | sperm associated antigen 9 | 0.0112863 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0112635 |
| CASC3 | cancer susceptibility candidate 3 | 0.0112048 |
| VEGFA | vascular endothelial growth factor A | 0.0111009 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.011019 |
| AFAP1 | actin filament associated protein 1 | 0.010999 |
| USP24 | ubiquitin specific peptidase 24 | 0.0109314 |
| RPS2 | ribosomal protein S2 | 0.0108416 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0108246 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0107851 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0107821 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0106357 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0106269 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.010571 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0105705 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.010545 |
| FOXJ3 | forkhead box J3 | 0.0105014 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0104726 |
| SETD5 | SET domain containing 5 | 0.01043 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.010367 |
| RPSA | ribosomal protein SA | 0.0103086 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0102593 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0102573 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0101931 |
| CABIN1 | calcineurin binding protein 1 | 0.00998359 |
| MATR3 | matrin 3 | 0.00997878 |
| HSPB11 | heat shock protein family B (small), member 11 | 0.00990215 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0098265 |
| SSRP1 | structure specific recognition protein 1 | 0.00980698 |
| LRRC59 | leucine rich repeat containing 59 | 0.00975099 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.00962342 |
| PCBP2 | poly(rC) binding protein 2 | 0.0096108 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.00948047 |
| GRB10 | growth factor receptor-bound protein 10 | 0.00942931 |
| SNX4 | sorting nexin 4 | 0.00942252 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.207261 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.197355 |
| CDH13 | cadherin 13 | -0.166308 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.14179 |
| EXT1 | exostosin glycosyltransferase 1 | -0.141774 |
| FN1 | fibronectin 1 | -0.140462 |
| VIM | vimentin | -0.139976 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.137695 |
| COL1A1 | collagen, type I, alpha 1 | -0.130909 |
| CD44 | CD44 molecule (Indian blood group) | -0.113546 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.100098 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0975997 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0944665 |
| COL1A2 | collagen, type I, alpha 2 | -0.0944213 |
| FBN1 | fibrillin 1 | -0.0885919 |
| ASPH | aspartate beta-hydroxylase | -0.0843676 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0834613 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0828393 |
| ENO1 | enolase 1, (alpha) | -0.0777584 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0769645 |
| IER3 | immediate early response 3 | -0.0720122 |
| LOX | lysyl oxidase | -0.0684015 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0671868 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0651061 |
| TMSB10 | thymosin beta 10 | -0.0640129 |
| MT2A | metallothionein 2A | -0.0627724 |
| CANX | calnexin | -0.0601442 |
| INHBA | inhibin, beta A | -0.052589 |
| LDHA | lactate dehydrogenase A | -0.0517979 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0511711 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0499485 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0472732 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0458459 |
| TPM4 | tropomyosin 4 | -0.0456351 |
| OSMR | oncostatin M receptor | -0.04557 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0452092 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0452089 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0451952 |
| FTL | ferritin, light polypeptide | -0.0448217 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.044488 |
| GLIS3 | GLIS family zinc finger 3 | -0.0441755 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0432969 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0432702 |
| NDRG1 | N-myc downstream regulated 1 | -0.0428049 |
| VCL | vinculin | -0.0425214 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0423407 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0411095 |
| COL5A1 | collagen, type V, alpha 1 | -0.0393526 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0375447 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0368864 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0366479 |
| LOXL2 | lysyl oxidase-like 2 | -0.0360456 |
| GOLGB1 | golgin B1 | -0.0360436 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0357935 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0357453 |
| HLA-B | major histocompatibility complex, class I, B | -0.0351064 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0348984 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0348324 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0348079 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0343112 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0342821 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0340092 |
| SMYD3 | SET and MYND domain containing 3 | -0.0336305 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0335188 |
| MAP1B | microtubule-associated protein 1B | -0.0333815 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0330726 |
| NAV1 | neuron navigator 1 | -0.0326984 |
| CADM1 | cell adhesion molecule 1 | -0.032591 |
| VCAN | versican | -0.0313616 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0313241 |
| ATXN1 | ataxin 1 | -0.0310955 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.031071 |
| RPL35A | ribosomal protein L35a | -0.0307176 |
| CNTN5 | contactin 5 | -0.030645 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0305619 |
| HMGA2 | high mobility group AT-hook 2 | -0.0305555 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0305264 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0302141 |
| STC1 | stanniocalcin 1 | -0.0299195 |
| CALD1 | caldesmon 1 | -0.029498 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0293508 |
| SQSTM1 | sequestosome 1 | -0.0291103 |
| FOXP1 | forkhead box P1 | -0.0289465 |
| RPS8 | ribosomal protein S8 | -0.0289462 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0287794 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.02865 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0279035 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0277884 |
| EGFR | epidermal growth factor receptor | -0.0275229 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0274569 |
| MTDH | metadherin | -0.027321 |
| IL6ST | interleukin 6 signal transducer | -0.0271804 |
| PALLD | palladin, cytoskeletal associated protein | -0.027083 |
| DST | dystonin | -0.0268811 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0267853 |
| COL3A1 | collagen, type III, alpha 1 | -0.0262446 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0261526 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0261158 |
| CTSB | cathepsin B | -0.0257943 |
| MYO10 | myosin X | -0.0257738 |
