| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.104986 |
| PLEC | plectin | 0.0386598 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0316335 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0308519 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0306318 |
| RPL3 | ribosomal protein L3 | 0.0291418 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0275894 |
| CALR | calreticulin | 0.0266227 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0257386 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0249999 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0231986 |
| HYOU1 | hypoxia up-regulated 1 | 0.0231111 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0211613 |
| RNF145 | ring finger protein 145 | 0.0209415 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0199244 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0197688 |
| GANAB | glucosidase, alpha; neutral AB | 0.0193379 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0193101 |
| RNF43 | ring finger protein 43 | 0.0184257 |
| MYO18A | myosin XVIIIA | 0.0183374 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0181682 |
| EPS8L1 | EPS8-like 1 | 0.0176906 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0174414 |
| FAM13A | family with sequence similarity 13, member A | 0.0170616 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0166166 |
| KRT8 | keratin 8, type II | 0.0150874 |
| XPOT | exportin, tRNA | 0.0149149 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0148876 |
| MLPH | melanophilin | 0.0147707 |
| TNS4 | tensin 4 | 0.0147564 |
| FLNA | filamin A, alpha | 0.0144676 |
| FBXO42 | F-box protein 42 | 0.0144011 |
| NUP58 | nucleoporin 58 | 0.0143887 |
| MKRN1 | makorin ring finger protein 1 | 0.0143661 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0140048 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0139303 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0138025 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0132983 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0130169 |
| TMEM41B | transmembrane protein 41B | 0.0129201 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0128716 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0127293 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0126274 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.012522 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0123861 |
| HOXB6 | homeobox B6 | 0.0122257 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0121456 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.0118391 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.011777 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.011661 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0116602 |
| INSIG2 | insulin induced gene 2 | 0.0115116 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0114486 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0113856 |
| LAMA5 | laminin, alpha 5 | 0.0113643 |
| KLC1 | kinesin light chain 1 | 0.0112493 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.011242 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0112085 |
| TNS1 | tensin 1 | 0.0111792 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.0108767 |
| ITGB4 | integrin, beta 4 | 0.0108505 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0108494 |
| C1D | C1D nuclear receptor corepressor | 0.0108021 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0107721 |
| TSPYL2 | TSPY-like 2 | 0.0107677 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0107241 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0106973 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.01068 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0106519 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0104975 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0104263 |
| CCNY | cyclin Y | 0.0103868 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.010293 |
| SRPRA | SRP receptor subunit alpha | 0.0102854 |
| STT3A | STT3A, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0102278 |
| CPSF6 | cleavage and polyadenylation specific factor 6, 68kDa | 0.0102176 |
| HOXB3 | homeobox B3 | 0.0102043 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.010109 |
| CEP250 | centrosomal protein 250kDa | 0.0100019 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.00999153 |
| HOXA3 | homeobox A3 | 0.00989228 |
| YPEL2 | yippee-like 2 (Drosophila) | 0.00972049 |
| CYTH2 | cytohesin 2 | 0.00966056 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.00964066 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0096253 |
| GOLGA3 | golgin A3 | 0.00959503 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0095579 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00955619 |
| BRD9 | bromodomain containing 9 | 0.00951279 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00946916 |
| EWSR1 | EWS RNA-binding protein 1 | 0.00935717 |
| RBM26 | RNA binding motif protein 26 | 0.0093073 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00927232 |
| PLXNB2 | plexin B2 | 0.00921138 |
| PFKP | phosphofructokinase, platelet | 0.00916604 |
| SAFB2 | scaffold attachment factor B2 | 0.00915957 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.00909012 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.00907481 |
| GRAMD1B | GRAM domain containing 1B | 0.00904704 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0089771 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175938 |
| EXT1 | exostosin glycosyltransferase 1 | -0.132757 |
| TJP1 | tight junction protein 1 | -0.130073 |
| RPS6 | ribosomal protein S6 | -0.124759 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.120529 |
| LMO7 | LIM domain 7 | -0.119637 |
| KRT20 | keratin 20, type I | -0.116925 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.113807 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.107767 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0927235 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0883754 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0868704 |
| FTL | ferritin, light polypeptide | -0.0847654 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0847457 |
| MYO1E | myosin IE | -0.0794416 |
| SMAD3 | SMAD family member 3 | -0.0746425 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.073951 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0733671 |
| ANXA2 | annexin A2 | -0.073125 |
| EGR1 | early growth response 1 | -0.0726557 |
| RPLP1 | ribosomal protein, large, P1 | -0.0714375 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0705669 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0679448 |
| LAMA4 | laminin, alpha 4 | -0.067675 |
| PTMA | prothymosin, alpha | -0.0665644 |
| EZR | ezrin | -0.0643806 |
| RPS8 | ribosomal protein S8 | -0.0616201 |
| LDHA | lactate dehydrogenase A | -0.060647 |
| TRIB1 | tribbles pseudokinase 1 | -0.0605418 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0602002 |
| VCL | vinculin | -0.0579543 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0577788 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0559158 |
| INTS6 | integrator complex subunit 6 | -0.0554066 |
| S100A10 | S100 calcium binding protein A10 | -0.0552071 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0542588 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0539692 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0536864 |
| RPS24 | ribosomal protein S24 | -0.0525872 |
| AREG | amphiregulin | -0.0525104 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0505609 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0503348 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0501531 |
| RPS2 | ribosomal protein S2 | -0.0500074 |
| RPS19 | ribosomal protein S19 | -0.0497025 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0496726 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0486606 |
| RPLP0 | ribosomal protein, large, P0 | -0.0481299 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0478304 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0476955 |
| RPL7 | ribosomal protein L7 | -0.0467347 |
| PTK2 | protein tyrosine kinase 2 | -0.0462274 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0460568 |
| TMEM123 | transmembrane protein 123 | -0.0459022 |
| RND3 | Rho family GTPase 3 | -0.0458459 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0448944 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0445741 |
| TMEM65 | transmembrane protein 65 | -0.0442184 |
| ASPH | aspartate beta-hydroxylase | -0.0437535 |
| FRY | furry homolog (Drosophila) | -0.0432866 |
| VMP1 | vacuole membrane protein 1 | -0.0432464 |
| LIMA1 | LIM domain and actin binding 1 | -0.0431647 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0431026 |
| RPL27A | ribosomal protein L27a | -0.0428831 |
| AHNAK | AHNAK nucleoprotein | -0.0427945 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0424047 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0418929 |
| PDZD8 | PDZ domain containing 8 | -0.0418345 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0415796 |
| RPS16 | ribosomal protein S16 | -0.0415444 |
| RPL28 | ribosomal protein L28 | -0.0413625 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.041049 |
| POF1B | premature ovarian failure, 1B | -0.0407035 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0405447 |
| RPS13 | ribosomal protein S13 | -0.040534 |
| RPLP2 | ribosomal protein, large, P2 | -0.0401693 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0401483 |
| RPS11 | ribosomal protein S11 | -0.040014 |
| RPL11 | ribosomal protein L11 | -0.0398741 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0391653 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0391261 |
| POTEF | POTE ankyrin domain family, member F | -0.0390838 |
| SGMS2 | sphingomyelin synthase 2 | -0.0390701 |
| ETV6 | ets variant 6 | -0.0385754 |
| RPS3 | ribosomal protein S3 | -0.0383993 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0381979 |
| RPS12 | ribosomal protein S12 | -0.0379591 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0377481 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0376689 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0375541 |
| RPS25 | ribosomal protein S25 | -0.0374921 |
| UBC | ubiquitin C | -0.0371129 |
| TMSB10 | thymosin beta 10 | -0.0368371 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0365675 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0363154 |
| RPL12 | ribosomal protein L12 | -0.0362567 |
| B2M | beta-2-microglobulin | -0.0361731 |
| RPL19 | ribosomal protein L19 | -0.0360854 |
| NTN4 | netrin 4 | -0.0359887 |
| RPL21 | ribosomal protein L21 | -0.0359115 |
