| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0991619 |
| PLEC | plectin | 0.0847522 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0443349 |
| EFHD2 | EF-hand domain family, member D2 | 0.0436753 |
| RPL3 | ribosomal protein L3 | 0.0409359 |
| CUL4B | cullin 4B | 0.0391813 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.038213 |
| PRELID2 | PRELI domain containing 2 | 0.0369484 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0366139 |
| MSN | moesin | 0.0352827 |
| KRT6A | keratin 6A, type II | 0.0284049 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0280346 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0260433 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.025334 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0249531 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0240359 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0239138 |
| BLCAP | bladder cancer associated protein | 0.0237645 |
| RPS2 | ribosomal protein S2 | 0.0236227 |
| NCOR2 | nuclear receptor corepressor 2 | 0.023401 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0230946 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0226941 |
| FNIP1 | folliculin interacting protein 1 | 0.0215701 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0215455 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0214182 |
| MCL1 | myeloid cell leukemia 1 | 0.0212218 |
| ANLN | anillin, actin binding protein | 0.0209305 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0201752 |
| C1D | C1D nuclear receptor corepressor | 0.0196877 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0195872 |
| GATA6 | GATA binding protein 6 | 0.0192562 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0189921 |
| CENPF | centromere protein F, 350/400kDa | 0.0187667 |
| TNS4 | tensin 4 | 0.0180237 |
| YEATS2 | YEATS domain containing 2 | 0.0178434 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0175694 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0174519 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0172189 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0169146 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0166925 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0166878 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.01648 |
| KIF16B | kinesin family member 16B | 0.0164682 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.01635 |
| EPHA2 | EPH receptor A2 | 0.0159231 |
| RPL21 | ribosomal protein L21 | 0.0158427 |
| CAPRIN2 | caprin family member 2 | 0.0158158 |
| CPNE1 | copine I | 0.0158132 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0156232 |
| FAM13A | family with sequence similarity 13, member A | 0.015426 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.015312 |
| ADD1 | adducin 1 (alpha) | 0.0151328 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0150702 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 0.0144413 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.014198 |
| PDE8A | phosphodiesterase 8A | 0.0140634 |
| TMF1 | TATA element modulatory factor 1 | 0.0140018 |
| FLOT1 | flotillin 1 | 0.0139111 |
| INSIG2 | insulin induced gene 2 | 0.0137294 |
| LAMA5 | laminin, alpha 5 | 0.0136318 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | 0.0135121 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.013227 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0131093 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0130753 |
| COL5A2 | collagen, type V, alpha 2 | 0.0129744 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0128678 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0128208 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0127814 |
| TFG | TRK-fused gene | 0.0126343 |
| OSBPL2 | oxysterol binding protein-like 2 | 0.0125894 |
| NBEA | neurobeachin | 0.0125106 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 | 0.0125046 |
| TMEM165 | transmembrane protein 165 | 0.0123321 |
| FLNA | filamin A, alpha | 0.0121674 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0121134 |
| HELZ | helicase with zinc finger | 0.0121013 |
| CDK19 | cyclin-dependent kinase 19 | 0.012091 |
| RPS25 | ribosomal protein S25 | 0.0120762 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0120487 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0120159 |
| BRD2 | bromodomain containing 2 | 0.0119535 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0119433 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0119378 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0118977 |
| UBAP1 | ubiquitin associated protein 1 | 0.011837 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0118019 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0117931 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.011757 |
| ANGPTL4 | angiopoietin-like 4 | 0.0117326 |
| RBM26 | RNA binding motif protein 26 | 0.0117135 |
| SRP54 | signal recognition particle 54kDa | 0.0116538 |
| FBXO42 | F-box protein 42 | 0.0115953 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0115679 |
| CEP250 | centrosomal protein 250kDa | 0.0114933 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0114206 |
| ANK1 | ankyrin 1, erythrocytic | 0.0114158 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0113431 |
| JPH2 | junctophilin 2 | 0.0113084 |
| KIAA2026 | KIAA2026 | 0.0112257 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0112209 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.339991 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.253662 |
| LMO7 | LIM domain 7 | -0.136903 |
| SULF1 | sulfatase 1 | -0.133203 |
| MTSS1 | metastasis suppressor 1 | -0.129468 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.127576 |
| ENO1 | enolase 1, (alpha) | -0.121791 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.119537 |
| DPYD | dihydropyrimidine dehydrogenase | -0.107654 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.100734 |
| RAI14 | retinoic acid induced 14 | -0.0982356 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0962116 |
| LDHA | lactate dehydrogenase A | -0.0946696 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0885484 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0870088 |
| CD44 | CD44 molecule (Indian blood group) | -0.085715 |
| AHNAK | AHNAK nucleoprotein | -0.0849175 |
| SULF2 | sulfatase 2 | -0.0816289 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0813105 |
| PODXL | podocalyxin-like | -0.0779908 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0710979 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0696832 |
| ANXA2 | annexin A2 | -0.0649664 |
| HLA-E | major histocompatibility complex, class I, E | -0.0645308 |
| UBC | ubiquitin C | -0.0632245 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0627367 |
| RASAL2 | RAS protein activator like 2 | -0.0620591 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0610676 |
| LAMC2 | laminin, gamma 2 | -0.0610105 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0599502 |
| FOXP1 | forkhead box P1 | -0.0594412 |
| OSMR | oncostatin M receptor | -0.0589779 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.05895 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0584465 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0580458 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0572411 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0567634 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0552788 |
| PLS3 | plastin 3 | -0.0551042 |
| RIGI | RNA sensor RIG-I | -0.0550363 |
| DOK5 | docking protein 5 | -0.054793 |
| PGK1 | phosphoglycerate kinase 1 | -0.0547477 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0542679 |
| FOXO1 | forkhead box O1 | -0.0539405 |
| PALLD | palladin, cytoskeletal associated protein | -0.0537757 |
| CANX | calnexin | -0.0524002 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0513041 |
| PTK2 | protein tyrosine kinase 2 | -0.0501775 |
| MECOM | MDS1 and EVI1 complex locus | -0.050087 |
| ASPH | aspartate beta-hydroxylase | -0.0494764 |
| AOPEP | aminopeptidase O (putative) | -0.0491465 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0490358 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0489871 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0482983 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0482599 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0475111 |
| POTEF | POTE ankyrin domain family, member F | -0.0468102 |
| CALB1 | calbindin 1, 28kDa | -0.0467052 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0454315 |
| NDRG1 | N-myc downstream regulated 1 | -0.0427191 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0424126 |
| ARPC5 | actin related protein 2/3 complex, subunit 5, 16kDa | -0.0423403 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0417492 |
| SMYD3 | SET and MYND domain containing 3 | -0.0414898 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0409258 |
| STC1 | stanniocalcin 1 | -0.0405589 |
| TMSB10 | thymosin beta 10 | -0.0405547 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0405407 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0403996 |
| TXNRD1 | thioredoxin reductase 1 | -0.0402805 |
| JMJD1C | jumonji domain containing 1C | -0.0388287 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.03872 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0385771 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.038328 |
| MYOF | myoferlin | -0.0382374 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0381322 |
| NEK7 | NIMA-related kinase 7 | -0.0377524 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0377024 |
| UTRN | utrophin | -0.0374481 |
| CDK6 | cyclin-dependent kinase 6 | -0.0372432 |
| ACTN4 | actinin, alpha 4 | -0.036773 |
| MYO10 | myosin X | -0.0366689 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0365777 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0364827 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0364552 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0361782 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.035773 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.035613 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0355239 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0352701 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0351321 |
| TAGLN2 | transgelin 2 | -0.0346803 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0344261 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0343705 |
| THBD | thrombomodulin | -0.0343198 |
| SQLE | squalene epoxidase | -0.0336887 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0336434 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0332648 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0331369 |
| CALU | calumenin | -0.0330882 |
