| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | 0.18046 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.161635 |
| ATP13A3 | ATPase type 13A3 | 0.155034 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.146768 |
| ZNF841 | zinc finger protein 841 | 0.139041 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0887133 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.082741 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0784527 |
| DST | dystonin | 0.0717814 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0699098 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0675879 |
| TMSB4X | thymosin beta 4, X-linked | 0.0614678 |
| FN1 | fibronectin 1 | 0.0582957 |
| SMAD3 | SMAD family member 3 | 0.0573099 |
| ZNF432 | zinc finger protein 432 | 0.0567177 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0564812 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0551672 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0543977 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0491895 |
| CALR | calreticulin | 0.0476586 |
| FLNB | filamin B, beta | 0.0474232 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0468661 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0466142 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0462184 |
| NAV2 | neuron navigator 2 | 0.0458339 |
| NUP58 | nucleoporin 58 | 0.045509 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0437281 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0427433 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0426773 |
| SET | SET nuclear proto-oncogene | 0.0423908 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0418368 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0411229 |
| SPAG9 | sperm associated antigen 9 | 0.0395825 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0388899 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0388884 |
| AFAP1 | actin filament associated protein 1 | 0.0384927 |
| RAI14 | retinoic acid induced 14 | 0.0382911 |
| ADM | adrenomedullin | 0.0378128 |
| AHNAK | AHNAK nucleoprotein | 0.0374716 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0372829 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0372194 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0368197 |
| NCKAP1 | NCK-associated protein 1 | 0.0366431 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0364711 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0359948 |
| ENO1 | enolase 1, (alpha) | 0.0355697 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0347956 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0347191 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0342668 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0341595 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0339022 |
| ASPH | aspartate beta-hydroxylase | 0.0338764 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0338638 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0337284 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.033692 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0335311 |
| YEATS2 | YEATS domain containing 2 | 0.0327374 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0325544 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0322959 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0319477 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.0313426 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0311876 |
| PTK2 | protein tyrosine kinase 2 | 0.0307452 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0307202 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0306357 |
| COL5A1 | collagen, type V, alpha 1 | 0.0305605 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0300597 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0300166 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0298463 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0294856 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0293586 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0293397 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0290718 |
| CEP250 | centrosomal protein 250kDa | 0.0287398 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0287368 |
| CANX | calnexin | 0.0285824 |
| H1-4 | H1.4 linker histone, cluster member | 0.028569 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0284279 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0283448 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0278277 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0277083 |
| MMP12 | matrix metallopeptidase 12 | 0.0275029 |
| CUL4B | cullin 4B | 0.0271845 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0269857 |
| PRELID2 | PRELI domain containing 2 | 0.026932 |
| TPD52 | tumor protein D52 | 0.0266134 |
| ANO6 | anoctamin 6 | 0.0258196 |
| ZNF292 | zinc finger protein 292 | 0.0257952 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0257847 |
| MYOF | myoferlin | 0.0256769 |
| STK4 | serine/threonine kinase 4 | 0.0255991 |
| DENND5A | DENN/MADD domain containing 5A | 0.0255976 |
| RLF | rearranged L-myc fusion | 0.0254263 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0250464 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0249953 |
| HMGB2 | high mobility group box 2 | 0.0247991 |
| TPM3 | tropomyosin 3 | 0.0246435 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0246196 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0246063 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0245996 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.312273 |
| FTL | ferritin, light polypeptide | -0.191905 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.137876 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.133046 |
| HLA-B | major histocompatibility complex, class I, B | -0.121002 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.119695 |
| NDRG1 | N-myc downstream regulated 1 | -0.103705 |
| MT2A | metallothionein 2A | -0.0835316 |
| POTEF | POTE ankyrin domain family, member F | -0.0646091 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0547442 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0518569 |
| MAP1B | microtubule-associated protein 1B | -0.0516927 |
| CTSD | cathepsin D | -0.0447999 |
| DEK | DEK proto-oncogene | -0.0437979 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0425534 |
| PFN1 | profilin 1 | -0.0394178 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.039268 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0380962 |
| MT1X | metallothionein 1X | -0.0375258 |
| TMSB10 | thymosin beta 10 | -0.037143 |
| ACTG1 | actin gamma 1 | -0.0364797 |
| LDHA | lactate dehydrogenase A | -0.0358359 |
| FOSL1 | FOS-like antigen 1 | -0.0351471 |
| VIM | vimentin | -0.0344917 |
| HMGA1 | high mobility group AT-hook 1 | -0.0340335 |
| EGR1 | early growth response 1 | -0.032165 |
| ERBIN | erbb2 interacting protein | -0.0313218 |
| RPS6 | ribosomal protein S6 | -0.0312911 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0310769 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0278559 |
| TXNRD1 | thioredoxin reductase 1 | -0.0275597 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0273255 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0271439 |
| MYADM | myeloid-associated differentiation marker | -0.0267543 |
| RPL28 | ribosomal protein L28 | -0.0266568 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0257136 |
| HLA-A | major histocompatibility complex, class I, A | -0.0245228 |
| ARF4 | ADP-ribosylation factor 4 | -0.0244876 |
| HMGB1 | high mobility group box 1 | -0.0244623 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0242594 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0241434 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0238564 |
| TAPBP | TAP binding protein (tapasin) | -0.0235638 |
| ANXA2 | annexin A2 | -0.0223719 |
| B2M | beta-2-microglobulin | -0.022085 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0220113 |
| TUBA1B | tubulin, alpha 1b | -0.0220044 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0217111 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0213525 |
| PFN2 | profilin 2 | -0.0212926 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0211595 |
| UFM1 | ubiquitin-fold modifier 1 | -0.021107 |
| BRD2 | bromodomain containing 2 | -0.0208479 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0207841 |
| TAGLN2 | transgelin 2 | -0.0205882 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0201427 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.019596 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0192372 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0191681 |
| LOX | lysyl oxidase | -0.0185587 |
| ATN1 | atrophin 1 | -0.0185187 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0183971 |
| RPL35A | ribosomal protein L35a | -0.0183005 |
| L1CAM | L1 cell adhesion molecule | -0.0182973 |
| PEA15 | phosphoprotein enriched in astrocytes 15 | -0.0179778 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0175974 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0172713 |
| CCND1 | cyclin D1 | -0.0170424 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0169992 |
| BSG | basigin (Ok blood group) | -0.0169533 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0169416 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0169201 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0164373 |
| RPL21 | ribosomal protein L21 | -0.0160643 |
| EHD2 | EH-domain containing 2 | -0.0158868 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0157714 |
| RTN4 | reticulon 4 | -0.0157561 |
| TUBA1C | tubulin, alpha 1c | -0.0157399 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.01555 |
| TUBB | tubulin, beta class I | -0.0154637 |
| NPPB | natriuretic peptide B | -0.0152638 |
| RPS13 | ribosomal protein S13 | -0.0151373 |
| CD99 | CD99 molecule | -0.0149981 |
| GNAS | GNAS complex locus | -0.0149544 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0149406 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0149359 |
| S100A10 | S100 calcium binding protein A10 | -0.0149115 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0148942 |
| LDHB | lactate dehydrogenase B | -0.0148895 |
| S100A6 | S100 calcium binding protein A6 | -0.0147017 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0140647 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.0139098 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0138989 |
| UBC | ubiquitin C | -0.0138724 |
| AXL | AXL receptor tyrosine kinase | -0.0137585 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0136894 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0136377 |
| RPS19 | ribosomal protein S19 | -0.0136161 |
| GRN | granulin | -0.0135213 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0134928 |
