| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.232767 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.183863 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.156792 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.155478 |
| HYOU1 | hypoxia up-regulated 1 | 0.119932 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.117827 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.101971 |
| DSPP | dentin sialophosphoprotein | 0.0873653 |
| TMSB4X | thymosin beta 4, X-linked | 0.0806614 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0787322 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0756679 |
| ANLN | anillin, actin binding protein | 0.0746433 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0710887 |
| CANX | calnexin | 0.0705991 |
| ATXN1 | ataxin 1 | 0.0657406 |
| CLTC | clathrin, heavy chain (Hc) | 0.0615099 |
| AHNAK | AHNAK nucleoprotein | 0.0599246 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0557802 |
| CALR | calreticulin | 0.0518222 |
| ASPH | aspartate beta-hydroxylase | 0.0515453 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0494353 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0492478 |
| GOLGA4 | golgin A4 | 0.0489288 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.048586 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0483385 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0478572 |
| TES | testin LIM domain protein | 0.0477775 |
| AHR | aryl hydrocarbon receptor | 0.0476297 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0466845 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0461631 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0454839 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0451834 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0446835 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0440263 |
| KRT17 | keratin 17, type I | 0.0436148 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0433851 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0433631 |
| SET | SET nuclear proto-oncogene | 0.0432491 |
| GOLGB1 | golgin B1 | 0.043247 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0421651 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0418241 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0407164 |
| HELZ | helicase with zinc finger | 0.040103 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0399994 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0398613 |
| EZR | ezrin | 0.0398142 |
| ANKRD11 | ankyrin repeat domain 11 | 0.039811 |
| XPO1 | exportin 1 | 0.0385097 |
| LMO7 | LIM domain 7 | 0.0384266 |
| KRT18 | keratin 18, type I | 0.0382149 |
| HMGB2 | high mobility group box 2 | 0.0373657 |
| PLEC | plectin | 0.0370159 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0366969 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0366744 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0365601 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0359888 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0358576 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0357892 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0357758 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.035683 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0353517 |
| DIAPH3 | diaphanous-related formin 3 | 0.0351005 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0349549 |
| ECT2 | epithelial cell transforming 2 | 0.0349046 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0346862 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0344334 |
| DST | dystonin | 0.0341392 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0340702 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0338536 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0336052 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0332533 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0331049 |
| TMF1 | TATA element modulatory factor 1 | 0.0327084 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0326983 |
| RPN1 | ribophorin I | 0.0325982 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0323048 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0322637 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0321709 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0321639 |
| FNIP1 | folliculin interacting protein 1 | 0.0320696 |
| H1-0 | H1.0 linker histone | 0.0319925 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0317311 |
| PCM1 | pericentriolar material 1 | 0.0315403 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.0311938 |
| SPAG9 | sperm associated antigen 9 | 0.0310425 |
| OGA | O-GlcNAcase | 0.0305246 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.030432 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.030314 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0301461 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0300835 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0300157 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0299839 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0298693 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0297679 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0295645 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.029321 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0293121 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0288775 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0286797 |
| AFDN | afadin, adherens junction formation factor | 0.0286606 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.211163 |
| EMP1 | epithelial membrane protein 1 | -0.100376 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0939486 |
| TMSB10 | thymosin beta 10 | -0.0849183 |
| NPSR1 | neuropeptide S receptor 1 | -0.0825248 |
| ANXA2 | annexin A2 | -0.0699608 |
| FTL | ferritin, light polypeptide | -0.0594275 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0579011 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0571465 |
| RPS25 | ribosomal protein S25 | -0.0545168 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0532957 |
| S100A10 | S100 calcium binding protein A10 | -0.0511981 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0496072 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0474521 |
| BCL2L1 | BCL2-like 1 | -0.046869 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0438005 |
| MCU | mitochondrial calcium uniporter | -0.0430415 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0427391 |
| RPS6 | ribosomal protein S6 | -0.042403 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0422305 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0419136 |
| CLDN4 | claudin 4 | -0.0411246 |
| NDRG1 | N-myc downstream regulated 1 | -0.0382564 |
| POTEF | POTE ankyrin domain family, member F | -0.0378507 |
| GPX2 | glutathione peroxidase 2 | -0.0378422 |
| S100A6 | S100 calcium binding protein A6 | -0.036593 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0358161 |
| RPL35A | ribosomal protein L35a | -0.0357338 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0343643 |
| JUP | junction plakoglobin | -0.0327274 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0323011 |
| EGR1 | early growth response 1 | -0.0321055 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0318655 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0318646 |
| TMEM45B | transmembrane protein 45B | -0.0315058 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0313204 |
| TPM4 | tropomyosin 4 | -0.0310736 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.030946 |
| RPL23 | ribosomal protein L23 | -0.0302886 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0301357 |
| TMC5 | transmembrane channel-like 5 | -0.0300753 |
| ATF5 | activating transcription factor 5 | -0.030075 |
| ITGB4 | integrin, beta 4 | -0.030072 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0299259 |
| LCN2 | lipocalin 2 | -0.0297854 |
| TMEM123 | transmembrane protein 123 | -0.0296815 |
| MUC1 | mucin 1, cell surface associated | -0.0291638 |
| FASN | fatty acid synthase | -0.0291248 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0289601 |
| FLNB | filamin B, beta | -0.028797 |
| MUC17 | mucin 17, cell surface associated | -0.028337 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0283164 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0282418 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0274919 |
| RPS24 | ribosomal protein S24 | -0.0273098 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0271369 |
| HLA-B | major histocompatibility complex, class I, B | -0.0263545 |
| TAPBP | TAP binding protein (tapasin) | -0.0262011 |
| RPL28 | ribosomal protein L28 | -0.0256678 |
| ACTG1 | actin gamma 1 | -0.0255911 |
| PRSS3 | protease, serine, 3 | -0.024922 |
| CLDN7 | claudin 7 | -0.0249038 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0247712 |
| MYO1E | myosin IE | -0.024716 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.024676 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0246309 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0245025 |
| PLSCR1 | phospholipid scramblase 1 | -0.0239541 |
| RPLP1 | ribosomal protein, large, P1 | -0.0237564 |
| KLK10 | kallikrein-related peptidase 10 | -0.023565 |
| HMGA1 | high mobility group AT-hook 1 | -0.0230049 |
| RPS16 | ribosomal protein S16 | -0.0229638 |
| HLA-E | major histocompatibility complex, class I, E | -0.0221432 |
| LAMA5 | laminin, alpha 5 | -0.0220775 |
| FOSL1 | FOS-like antigen 1 | -0.0220705 |
| TOB1 | transducer of ERBB2, 1 | -0.0219947 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0219862 |
| INSIG1 | insulin induced gene 1 | -0.0219707 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0219094 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0216454 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0215445 |
| RACK1 | receptor for activated C kinase 1 | -0.0214482 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0213795 |
| HLA-A | major histocompatibility complex, class I, A | -0.0210436 |
| ABLIM1 | actin binding LIM protein 1 | -0.020857 |
| RPL36A | ribosomal protein L36a | -0.0208241 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0205685 |
| KRT7 | keratin 7, type II | -0.0205182 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0203428 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.020209 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0200995 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.0200861 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0200423 |
| RPL30 | ribosomal protein L30 | -0.0200055 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0199055 |
| TTYH3 | tweety family member 3 | -0.019899 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0197722 |
| FOXQ1 | forkhead box Q1 | -0.0195661 |
| MX2 | MX dynamin-like GTPase 2 | -0.0194883 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0193952 |
