| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.132007 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.12993 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.116528 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.11555 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.113698 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.108457 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0869249 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0835117 |
| ZNF292 | zinc finger protein 292 | 0.0815853 |
| NUP58 | nucleoporin 58 | 0.0814254 |
| PKM | pyruvate kinase, muscle | 0.0791326 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0790628 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0789235 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0788136 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.075969 |
| PGK1 | phosphoglycerate kinase 1 | 0.0723898 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0721745 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0693913 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0683574 |
| DST | dystonin | 0.0664615 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0661748 |
| AHNAK | AHNAK nucleoprotein | 0.0654558 |
| PTMA | prothymosin, alpha | 0.0653554 |
| APP | amyloid beta (A4) precursor protein | 0.0647498 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.063032 |
| ASPH | aspartate beta-hydroxylase | 0.0621837 |
| SPAG9 | sperm associated antigen 9 | 0.0616379 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0609605 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0605091 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0599975 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.058878 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0560823 |
| GPC6 | glypican 6 | 0.0560231 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0555588 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0541253 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0536165 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0527633 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0515165 |
| WDR45B | WD repeat domain 45B | 0.0513898 |
| ATP13A3 | ATPase type 13A3 | 0.0510776 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0506882 |
| NCKAP1 | NCK-associated protein 1 | 0.0502808 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0488744 |
| DTNA | dystrobrevin, alpha | 0.0487883 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0478999 |
| MED13L | mediator complex subunit 13-like | 0.0471561 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0463221 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.04611 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.045996 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0459582 |
| MMP12 | matrix metallopeptidase 12 | 0.0455649 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0448517 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0443311 |
| ENO1 | enolase 1, (alpha) | 0.0442091 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0438203 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0436239 |
| MSN | moesin | 0.0434658 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0434201 |
| RLF | rearranged L-myc fusion | 0.0434054 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.043086 |
| HELZ | helicase with zinc finger | 0.042556 |
| RUNX1 | runt-related transcription factor 1 | 0.0425205 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0424114 |
| FMNL2 | formin-like 2 | 0.0423703 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0422436 |
| TPM3 | tropomyosin 3 | 0.042145 |
| RPL4 | ribosomal protein L4 | 0.0418915 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.041553 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0412505 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0412114 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0411308 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0410371 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0404436 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0403165 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0402111 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0393652 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.039049 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0390339 |
| CD109 | CD109 molecule | 0.0387169 |
| CANX | calnexin | 0.0386459 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0383563 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0380766 |
| KIF5B | kinesin family member 5B | 0.0377551 |
| RAB8B | RAB8B, member RAS oncogene family | 0.037467 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0373445 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0373105 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0372944 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.037257 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0371229 |
| RPS3 | ribosomal protein S3 | 0.0369622 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0363324 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0361807 |
| OGA | O-GlcNAcase | 0.0359792 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0357426 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0352479 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0350128 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0341759 |
| SET | SET nuclear proto-oncogene | 0.0341359 |
| MATR3 | matrin 3 | 0.0340663 |
| PLEC | plectin | 0.0340564 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.237578 |
| EGR1 | early growth response 1 | -0.105973 |
| VIM | vimentin | -0.0759806 |
| LSAMP | limbic system-associated membrane protein | -0.0750844 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0526864 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0517336 |
| NABP1 | nucleic acid binding protein 1 | -0.0389957 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0385394 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0355695 |
| HMGA1 | high mobility group AT-hook 1 | -0.0345923 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0328201 |
| NDRG1 | N-myc downstream regulated 1 | -0.0306854 |
| HDAC9 | histone deacetylase 9 | -0.0290497 |
| NTM | neurotrimin | -0.0290163 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0288003 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0283155 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0272211 |
| TMSB10 | thymosin beta 10 | -0.0267326 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0259452 |
| ADAM19 | ADAM metallopeptidase domain 19 | -0.023684 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0234502 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0232596 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0231517 |
| POTEF | POTE ankyrin domain family, member F | -0.0230904 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0221288 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0217452 |
| RPS6 | ribosomal protein S6 | -0.0213972 |
| NETO1 | neuropilin (NRP) and tolloid (TLL)-like 1 | -0.021335 |
| MYO10 | myosin X | -0.0211213 |
| INTS6 | integrator complex subunit 6 | -0.0210883 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0208997 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0203477 |
| FOXP1 | forkhead box P1 | -0.0201504 |
| PTCHD4 | patched domain containing 4 | -0.0199892 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0194775 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0193625 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.018117 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0177691 |
| CDH13 | cadherin 13 | -0.0177551 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0176584 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0174643 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0171371 |
| HMGA2 | high mobility group AT-hook 2 | -0.0171006 |
| RPL35A | ribosomal protein L35a | -0.0168457 |
| MYADM | myeloid-associated differentiation marker | -0.0167095 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0165168 |
| RPL28 | ribosomal protein L28 | -0.0164856 |
| CCN2 | cellular communication network factor 2 | -0.0162808 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0162694 |
| ESM1 | endothelial cell-specific molecule 1 | -0.0162619 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0158828 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 | -0.0158543 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0156973 |
| CD163L1 | CD163 molecule-like 1 | -0.0156907 |
| ZNF804A | zinc finger protein 804A | -0.0156008 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0155228 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0148735 |
| FLNC | filamin C, gamma | -0.0144387 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.0139243 |
| NAV3 | neuron navigator 3 | -0.0136079 |
| DGKI | diacylglycerol kinase, iota | -0.013394 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.013129 |
| ETV6 | ets variant 6 | -0.0130843 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0128836 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.012852 |
| FOSL1 | FOS-like antigen 1 | -0.0127627 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0125479 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.012525 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0125206 |
| ASTN2 | astrotactin 2 | -0.0125103 |
| COL27A1 | collagen, type XXVII, alpha 1 | -0.0123256 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0122867 |
| VCL | vinculin | -0.0122825 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0120674 |
| DHFR | dihydrofolate reductase | -0.012039 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0120102 |
| RPS25 | ribosomal protein S25 | -0.0119524 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0117263 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0115693 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | -0.0115271 |
| KYNU | kynureninase | -0.0111617 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.011036 |
| TEX14 | testis expressed 14 | -0.0108469 |
| SHISA5 | shisa family member 5 | -0.0108043 |
| ATN1 | atrophin 1 | -0.010785 |
| TNNC1 | troponin C type 1 (slow) | -0.0106864 |
| SCG5 | secretogranin V | -0.0106452 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0106142 |
| FGF5 | fibroblast growth factor 5 | -0.0103646 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.010278 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.010197 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0101471 |
| CLMP | CXADR-like membrane protein | -0.0100722 |
| RPL21 | ribosomal protein L21 | -0.0100715 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0100584 |
| RGMB | repulsive guidance molecule family member b | -0.00995374 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.00982388 |
| PRDM1 | PR domain containing 1, with ZNF domain | -0.00975477 |
| NLK | nemo-like kinase | -0.00963986 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.00949134 |
