| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSPP | dentin sialophosphoprotein | 0.154088 |
| PTMA | prothymosin, alpha | 0.14856 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.129084 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.128892 |
| KRT18 | keratin 18, type I | 0.125592 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.113433 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.109674 |
| FAT1 | FAT atypical cadherin 1 | 0.108102 |
| NPSR1 | neuropeptide S receptor 1 | 0.0961657 |
| TMSB4X | thymosin beta 4, X-linked | 0.0887717 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0781012 |
| FAM13A | family with sequence similarity 13, member A | 0.0747444 |
| RPS2 | ribosomal protein S2 | 0.071897 |
| KRT8 | keratin 8, type II | 0.0713312 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0684021 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.067756 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0644916 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0623048 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0595794 |
| ITGA6 | integrin, alpha 6 | 0.0563574 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0562006 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0550492 |
| RPL3 | ribosomal protein L3 | 0.0549981 |
| PRELID2 | PRELI domain containing 2 | 0.0540391 |
| EZR | ezrin | 0.0513707 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.0508725 |
| PLEC | plectin | 0.0508188 |
| CCNY | cyclin Y | 0.0483087 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0465302 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0459561 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0456961 |
| PIGR | polymeric immunoglobulin receptor | 0.0452662 |
| MLEC | malectin | 0.0451953 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0446254 |
| RNF217 | ring finger protein 217 | 0.0440358 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0439406 |
| CALR | calreticulin | 0.0434311 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.042602 |
| EREG | epiregulin | 0.0423888 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0419345 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0414444 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0411415 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0410566 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0408412 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0406575 |
| TNS4 | tensin 4 | 0.0406046 |
| FLNB | filamin B, beta | 0.0399376 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0393418 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0379618 |
| SET | SET nuclear proto-oncogene | 0.0362624 |
| H1-4 | H1.4 linker histone, cluster member | 0.0359388 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0352869 |
| LMNA | lamin A/C | 0.03519 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0345792 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0345579 |
| TPM3 | tropomyosin 3 | 0.0343178 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0339433 |
| XPOT | exportin, tRNA | 0.0337741 |
| RNF145 | ring finger protein 145 | 0.033367 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0333072 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.033199 |
| PNN | pinin, desmosome associated protein | 0.0330603 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0330367 |
| TPR | translocated promoter region, nuclear basket protein | 0.0319953 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0319942 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0319101 |
| CENPF | centromere protein F, 350/400kDa | 0.0318176 |
| SSR1 | signal sequence receptor, alpha | 0.0317601 |
| YME1L1 | YME1-like 1 ATPase | 0.0316013 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0315531 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0314238 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0313749 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0311363 |
| TMF1 | TATA element modulatory factor 1 | 0.030819 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0306407 |
| SPAG9 | sperm associated antigen 9 | 0.0305052 |
| KLC1 | kinesin light chain 1 | 0.0302007 |
| ONECUT3 | one cut homeobox 3 | 0.0300748 |
| CALB1 | calbindin 1, 28kDa | 0.0300217 |
| RPL7A | ribosomal protein L7a | 0.0299553 |
| GLCE | glucuronic acid epimerase | 0.0298597 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.029531 |
| AREG | amphiregulin | 0.0293018 |
| FNBP1L | formin binding protein 1-like | 0.0289655 |
| GOLGB1 | golgin B1 | 0.0285075 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0284291 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0281316 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0281162 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0280767 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0274931 |
| RPL4 | ribosomal protein L4 | 0.0274602 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0273519 |
| DENND1A | DENN/MADD domain containing 1A | 0.0273282 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0272905 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0271924 |
| TPD52 | tumor protein D52 | 0.0271813 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0268012 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0266017 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0265649 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0265262 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.478929 |
| UBC | ubiquitin C | -0.101538 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0917716 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0739766 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0684199 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0592764 |
| ANXA2 | annexin A2 | -0.0580704 |
| HMGA1 | high mobility group AT-hook 1 | -0.0562098 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0561696 |
| POTEF | POTE ankyrin domain family, member F | -0.0544554 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0539681 |
| RPS27A | ribosomal protein S27a | -0.0536084 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0506721 |
| LDHA | lactate dehydrogenase A | -0.0496886 |
| RPLP1 | ribosomal protein, large, P1 | -0.0486854 |
| FTL | ferritin, light polypeptide | -0.0469585 |
| TMSB10 | thymosin beta 10 | -0.0447896 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0440133 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0393431 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0391368 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.039055 |
| PCBP2 | poly(rC) binding protein 2 | -0.0370184 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0360502 |
| RPL23 | ribosomal protein L23 | -0.036038 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0360276 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0330795 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0325081 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0316877 |
| MYO1E | myosin IE | -0.0316119 |
| RPS24 | ribosomal protein S24 | -0.0314938 |
| ENO1 | enolase 1, (alpha) | -0.0298826 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.028125 |
| JUN | jun proto-oncogene | -0.0280633 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0280162 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0269978 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0262498 |
| PTEN | phosphatase and tensin homolog | -0.0260582 |
| TRIM2 | tripartite motif containing 2 | -0.0260097 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.025437 |
| CLDN7 | claudin 7 | -0.0248144 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0246971 |
| TXNRD1 | thioredoxin reductase 1 | -0.0244272 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0240011 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0237351 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0233117 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0232963 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0228332 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0226475 |
| EGR1 | early growth response 1 | -0.0220655 |
| ATXN1 | ataxin 1 | -0.0219466 |
| BSG | basigin (Ok blood group) | -0.0209419 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0206469 |
| RHEB | Ras homolog enriched in brain | -0.0204499 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0203497 |
| CCNI | cyclin I | -0.0202221 |
| RPL28 | ribosomal protein L28 | -0.0198499 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0196525 |
| VMP1 | vacuole membrane protein 1 | -0.0195929 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0195613 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0190264 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.0189776 |
| RPS15 | ribosomal protein S15 | -0.018864 |
| HMGB1 | high mobility group box 1 | -0.0184084 |
| CTSD | cathepsin D | -0.018196 |
| AGRN | agrin | -0.0181242 |
| TMEM165 | transmembrane protein 165 | -0.0180497 |
| S100A6 | S100 calcium binding protein A6 | -0.0177575 |
| RPL5 | ribosomal protein L5 | -0.0177415 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0176483 |
| YBX1 | Y box binding protein 1 | -0.0176149 |
| CAPNS1 | calpain, small subunit 1 | -0.0175367 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0174686 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0173214 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0172704 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0171275 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0170382 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0169951 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0167603 |
| ARF4 | ADP-ribosylation factor 4 | -0.0167513 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0163549 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0163522 |
| GUK1 | guanylate kinase 1 | -0.0162786 |
| CLDN4 | claudin 4 | -0.0161298 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | -0.0160482 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0159833 |
| PERP | PERP, TP53 apoptosis effector | -0.0159144 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0158961 |
| TOB1 | transducer of ERBB2, 1 | -0.0158393 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | -0.015839 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0155413 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0153583 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | -0.0153322 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0153279 |
| FOXN3 | forkhead box N3 | -0.0153161 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0153093 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0152326 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0152223 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | -0.015192 |
| ATP11B | ATPase, class VI, type 11B | -0.0151197 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0150141 |
