| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0654615 |
| RPL23 | ribosomal protein L23 | 0.0540691 |
| RPS19 | ribosomal protein S19 | 0.0472333 |
| RPS12 | ribosomal protein S12 | 0.0445303 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0418651 |
| TMSB10 | thymosin beta 10 | 0.0417523 |
| RPL35A | ribosomal protein L35a | 0.0400659 |
| RPL3 | ribosomal protein L3 | 0.0388911 |
| RPL36 | ribosomal protein L36 | 0.0379845 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0377337 |
| HLA-B | major histocompatibility complex, class I, B | 0.0372153 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0370922 |
| RPL37A | ribosomal protein L37a | 0.0358754 |
| PRELID2 | PRELI domain containing 2 | 0.0357746 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0343779 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0338248 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0331296 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0327148 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0318431 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.031577 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0306286 |
| PDE8A | phosphodiesterase 8A | 0.030351 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.029509 |
| RPS17 | ribosomal protein S17 | 0.0274253 |
| B2M | beta-2-microglobulin | 0.0274232 |
| ANKRD11 | ankyrin repeat domain 11 | 0.027335 |
| PLEC | plectin | 0.0269439 |
| RPL37 | ribosomal protein L37 | 0.0268801 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0265083 |
| RPLP2 | ribosomal protein, large, P2 | 0.0264566 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0264223 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0262777 |
| HLA-A | major histocompatibility complex, class I, A | 0.0255482 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0246009 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0242601 |
| RPL35 | ribosomal protein L35 | 0.0238875 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.023876 |
| RPS27 | ribosomal protein S27 | 0.0237934 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.023735 |
| CALR | calreticulin | 0.0237167 |
| PKM | pyruvate kinase, muscle | 0.0236631 |
| FOSL1 | FOS-like antigen 1 | 0.0233998 |
| PCBP2 | poly(rC) binding protein 2 | 0.02324 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0229925 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0227336 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0225696 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0218957 |
| SLK | STE20-like kinase | 0.0217559 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0211611 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0209503 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0201137 |
| CEP250 | centrosomal protein 250kDa | 0.0198932 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0198083 |
| KLC1 | kinesin light chain 1 | 0.0197711 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0197024 |
| RPL36A | ribosomal protein L36a | 0.019649 |
| RPL31 | ribosomal protein L31 | 0.0190884 |
| SMIM44 | small integral membrane protein 44 | 0.0189507 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0188041 |
| CAPRIN2 | caprin family member 2 | 0.0184348 |
| MYO18A | myosin XVIIIA | 0.0184249 |
| MINK1 | misshapen-like kinase 1 | 0.018322 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0182478 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0182297 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0181545 |
| CABIN1 | calcineurin binding protein 1 | 0.0178938 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0178591 |
| VEGFA | vascular endothelial growth factor A | 0.0178247 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0177259 |
| RPL34 | ribosomal protein L34 | 0.0176719 |
| HDGF | hepatoma-derived growth factor | 0.0176027 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0173133 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0171231 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.017066 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0169386 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0167186 |
| PCDH1 | protocadherin 1 | 0.0166519 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.01664 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0165454 |
| RPL27 | ribosomal protein L27 | 0.0164876 |
| RPS3 | ribosomal protein S3 | 0.0164393 |
| CTBP2 | C-terminal binding protein 2 | 0.0163781 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0163428 |
| ANGPTL4 | angiopoietin-like 4 | 0.0161758 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0161225 |
| SRSF3 | serine/arginine-rich splicing factor 3 | 0.0159708 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0159437 |
| RPS11 | ribosomal protein S11 | 0.0159042 |
| RREB1 | ras responsive element binding protein 1 | 0.0158633 |
| CCNL1 | cyclin L1 | 0.015812 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0157322 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0156976 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0155803 |
| RPLP1 | ribosomal protein, large, P1 | 0.0155678 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0155154 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.015079 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0150631 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0147186 |
| RPL26 | ribosomal protein L26 | 0.0147023 |
| STX1A | syntaxin 1A (brain) | 0.0146677 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.379386 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.191632 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.15202 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.151966 |
| TXNRD1 | thioredoxin reductase 1 | -0.147914 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141204 |
| CD44 | CD44 molecule (Indian blood group) | -0.129919 |
| CANX | calnexin | -0.120168 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.105345 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0988237 |
| RAI1 | retinoic acid induced 1 | -0.0933139 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0911834 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0828913 |
| AHNAK | AHNAK nucleoprotein | -0.0806075 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0805654 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0729859 |
| CENPF | centromere protein F, 350/400kDa | -0.0669896 |
| LDHA | lactate dehydrogenase A | -0.0663841 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0643902 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0640897 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0634667 |
| TP63 | tumor protein p63 | -0.0631616 |
| USP34 | ubiquitin specific peptidase 34 | -0.0577551 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0541427 |
| EHBP1 | EH domain binding protein 1 | -0.0534091 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0534052 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0521812 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0516743 |
| HDLBP | high density lipoprotein binding protein | -0.0514907 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0513887 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0511633 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.050951 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0506029 |
| APP | amyloid beta (A4) precursor protein | -0.0505053 |
| PODXL | podocalyxin-like | -0.0474189 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0470447 |
| SPAG9 | sperm associated antigen 9 | -0.0468029 |
| VIM | vimentin | -0.0467067 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0464086 |
| MKI67 | marker of proliferation Ki-67 | -0.0457617 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0436459 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0431246 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0423471 |
| EMP1 | epithelial membrane protein 1 | -0.0421386 |
| EREG | epiregulin | -0.0421226 |
| ZNF217 | zinc finger protein 217 | -0.0415005 |
| HMGA1 | high mobility group AT-hook 1 | -0.0413479 |
| RIGI | RNA sensor RIG-I | -0.0410418 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0402321 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0401661 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0398471 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0397185 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.03874 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0383678 |
| CMIP | c-Maf inducing protein | -0.0383429 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0378227 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0376656 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.037188 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0369547 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0369007 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.036755 |
| CLTC | clathrin, heavy chain (Hc) | -0.0362966 |
| FBXO11 | F-box protein 11 | -0.036208 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0361492 |
| LMAN1 | lectin, mannose-binding, 1 | -0.036109 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0352463 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0352096 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0349823 |
| TAOK1 | TAO kinase 1 | -0.0345412 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0339103 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0337772 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0331507 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0329626 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0329493 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0329446 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0324783 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.032185 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0319786 |
| RGS4 | regulator of G-protein signaling 4 | -0.0318668 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0317841 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0316326 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0316119 |
| CDCP1 | CUB domain containing protein 1 | -0.0314588 |
| ACTG1 | actin gamma 1 | -0.0310636 |
| PDE10A | phosphodiesterase 10A | -0.0309661 |
| IPO7 | importin 7 | -0.0308504 |
| PGK1 | phosphoglycerate kinase 1 | -0.0305913 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0305823 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0304871 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0303772 |
| ANXA2 | annexin A2 | -0.0303702 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0299691 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0297346 |
| UBC | ubiquitin C | -0.0295979 |
| ENO1 | enolase 1, (alpha) | -0.0294839 |
| SETX | senataxin | -0.0294071 |
| JMJD1C | jumonji domain containing 1C | -0.0293042 |
| ANXA1 | annexin A1 | -0.0292384 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0291217 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0288847 |
