| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.0938882 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0739175 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0639106 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0550667 |
| CES1 | carboxylesterase 1 | 0.0545685 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0544128 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0502094 |
| TOP1 | topoisomerase (DNA) I | 0.0496635 |
| PLEC | plectin | 0.048194 |
| HYOU1 | hypoxia up-regulated 1 | 0.047292 |
| RNF145 | ring finger protein 145 | 0.0455552 |
| NGLY1 | N-glycanase 1 | 0.0398999 |
| ARRDC3 | arrestin domain containing 3 | 0.0393524 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0386111 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0373833 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0357432 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0354602 |
| DSPP | dentin sialophosphoprotein | 0.034103 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0340629 |
| HELZ | helicase with zinc finger | 0.033714 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0334695 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.031491 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0313351 |
| OGA | O-GlcNAcase | 0.0311637 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0310679 |
| TPD52 | tumor protein D52 | 0.0298574 |
| TMEM165 | transmembrane protein 165 | 0.0274061 |
| RUNX1 | runt-related transcription factor 1 | 0.0269634 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.026649 |
| ATP13A3 | ATPase type 13A3 | 0.0264356 |
| FNIP1 | folliculin interacting protein 1 | 0.026154 |
| WDR45B | WD repeat domain 45B | 0.0256749 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0255113 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.024342 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0241989 |
| NCKAP1 | NCK-associated protein 1 | 0.0240088 |
| NDE1 | nudE neurodevelopment protein 1 | 0.0230096 |
| SPAG9 | sperm associated antigen 9 | 0.0226348 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.022495 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.02243 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0224231 |
| SUCO | SUN domain containing ossification factor | 0.0224051 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0220675 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0220357 |
| YEATS2 | YEATS domain containing 2 | 0.0220144 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0217559 |
| RPL3 | ribosomal protein L3 | 0.0217302 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0211738 |
| ZNF292 | zinc finger protein 292 | 0.0210999 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0208353 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0207053 |
| NUP58 | nucleoporin 58 | 0.020629 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0203498 |
| TFG | TRK-fused gene | 0.0200806 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0200747 |
| SRP54 | signal recognition particle 54kDa | 0.0198155 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0195462 |
| KLC1 | kinesin light chain 1 | 0.0195218 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0194261 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0191549 |
| MKI67 | marker of proliferation Ki-67 | 0.0191267 |
| YAP1 | Yes-associated protein 1 | 0.0190976 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0190323 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0189326 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0188766 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0188611 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0181949 |
| TMF1 | TATA element modulatory factor 1 | 0.0179936 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0179129 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0177889 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0177037 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0175716 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | 0.0173355 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0172108 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.017152 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0170471 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0170064 |
| FRY | furry homolog (Drosophila) | 0.0169627 |
| ANXA5 | annexin A5 | 0.0169592 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0166606 |
| ATG14 | autophagy related 14 | 0.0166153 |
| CCNG2 | cyclin G2 | 0.016602 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0165428 |
| HDLBP | high density lipoprotein binding protein | 0.0165336 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.016518 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0164598 |
| UVRAG | UV radiation resistance associated | 0.0162917 |
| NPTN | neuroplastin | 0.0162874 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0162811 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0161507 |
| RBM26 | RNA binding motif protein 26 | 0.0160382 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0159273 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0158271 |
| PCBP2 | poly(rC) binding protein 2 | 0.0157333 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0156961 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.0156609 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0156376 |
| INSIG2 | insulin induced gene 2 | 0.0155973 |
| WASF2 | WAS protein family, member 2 | 0.0155541 |
| SEPTIN2 | septin 2 | 0.0155378 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.531682 |
| TMSB10 | thymosin beta 10 | -0.147623 |
| EGFR | epidermal growth factor receptor | -0.115836 |
| ASPH | aspartate beta-hydroxylase | -0.108916 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0987259 |
| MT2A | metallothionein 2A | -0.0971212 |
| EGR1 | early growth response 1 | -0.0883019 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0837115 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0797619 |
| ACTG1 | actin gamma 1 | -0.0790189 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0732373 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0692865 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0683989 |
| S100A10 | S100 calcium binding protein A10 | -0.0610622 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0603 |
| RPLP1 | ribosomal protein, large, P1 | -0.0592968 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0592285 |
| LOC112694756 | uncharaterized LOC112694756 | -0.057443 |
| FTL | ferritin, light polypeptide | -0.0569967 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0567121 |
| LDHA | lactate dehydrogenase A | -0.0533899 |
| CST3 | cystatin C | -0.0523021 |
| RPL35A | ribosomal protein L35a | -0.0522686 |
| ANXA2 | annexin A2 | -0.0513724 |
| PKM | pyruvate kinase, muscle | -0.0507848 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0504822 |
| NDRG1 | N-myc downstream regulated 1 | -0.0500202 |
| MYO1E | myosin IE | -0.0474088 |
| EFNA5 | ephrin-A5 | -0.0460242 |
| RNF213 | ring finger protein 213 | -0.0457925 |
| SEC61G | Sec61 gamma subunit | -0.0454315 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0451588 |
| TXNRD1 | thioredoxin reductase 1 | -0.0450268 |
| OSMR | oncostatin M receptor | -0.0445854 |
| STC1 | stanniocalcin 1 | -0.0445851 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0443089 |
| NABP1 | nucleic acid binding protein 1 | -0.0427966 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0426668 |
| VCL | vinculin | -0.0423911 |
| RPS24 | ribosomal protein S24 | -0.0412689 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0407602 |
| FOXP1 | forkhead box P1 | -0.0401093 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0394215 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0389218 |
| CCND1 | cyclin D1 | -0.0389146 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0387499 |
| SLTM | SAFB-like, transcription modulator | -0.038046 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0376719 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0376678 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0375611 |
| INTS6 | integrator complex subunit 6 | -0.0374427 |
| HLA-B | major histocompatibility complex, class I, B | -0.0369334 |
| RPS25 | ribosomal protein S25 | -0.0368351 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0363606 |
| RPL31 | ribosomal protein L31 | -0.0358931 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0355129 |
| B2M | beta-2-microglobulin | -0.0346002 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0343202 |
| KRT7 | keratin 7, type II | -0.0335697 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0334867 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0332614 |
| IER3 | immediate early response 3 | -0.0325836 |
| MYOF | myoferlin | -0.0323639 |
| RPS6 | ribosomal protein S6 | -0.0322942 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0317519 |
| AREG | amphiregulin | -0.0316778 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0316659 |
| SP100 | SP100 nuclear antigen | -0.0315677 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0304379 |
| MYO1D | myosin ID | -0.0304231 |
| CMIP | c-Maf inducing protein | -0.0301534 |
| RPL34 | ribosomal protein L34 | -0.0295065 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0292915 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.02876 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0286407 |
| TJP1 | tight junction protein 1 | -0.0285635 |
| CAV2 | caveolin 2 | -0.028445 |
| HMGA1 | high mobility group AT-hook 1 | -0.0279691 |
| LMO7 | LIM domain 7 | -0.0279402 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0278266 |
| PTMA | prothymosin, alpha | -0.0273356 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0272286 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0271808 |
| TNS3 | tensin 3 | -0.027163 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0271449 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0268884 |
| RPS8 | ribosomal protein S8 | -0.0267528 |
| RPS23 | ribosomal protein S23 | -0.0267225 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0262779 |
| S100A11 | S100 calcium binding protein A11 | -0.0258322 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0255753 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0254183 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0251695 |
| GRAMD1B | GRAM domain containing 1B | -0.0251574 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0251168 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0250011 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0246898 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0246543 |
| RPS3 | ribosomal protein S3 | -0.0244987 |
| RPLP0 | ribosomal protein, large, P0 | -0.0244427 |
