| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.202466 |
| TXNRD1 | thioredoxin reductase 1 | 0.154295 |
| GRAMD1B | GRAM domain containing 1B | 0.152073 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.124403 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103562 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0933964 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0911274 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0786261 |
| FGB | fibrinogen beta chain | 0.0761087 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0663859 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0647432 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0644833 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0604139 |
| RPL4 | ribosomal protein L4 | 0.0602608 |
| TPM3 | tropomyosin 3 | 0.060112 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0595206 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.055419 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0533643 |
| PTMA | prothymosin, alpha | 0.0529201 |
| ASPH | aspartate beta-hydroxylase | 0.0526388 |
| RPS12 | ribosomal protein S12 | 0.0507539 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0506075 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0496815 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0492823 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0491108 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0481449 |
| WDR43 | WD repeat domain 43 | 0.0481195 |
| WWOX | WW domain containing oxidoreductase | 0.0456131 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0455106 |
| NNMT | nicotinamide N-methyltransferase | 0.0427727 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0427211 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0427117 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0424034 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0413607 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0411973 |
| CENPF | centromere protein F, 350/400kDa | 0.0389651 |
| AHR | aryl hydrocarbon receptor | 0.0389176 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.038664 |
| RTN4 | reticulon 4 | 0.0377738 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0375041 |
| RPS2 | ribosomal protein S2 | 0.0371179 |
| YBX3 | Y box binding protein 3 | 0.0367152 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0366745 |
| RPL23 | ribosomal protein L23 | 0.0356767 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0349209 |
| RPL7 | ribosomal protein L7 | 0.0348835 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0344589 |
| RPL19 | ribosomal protein L19 | 0.0344572 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0344322 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.03302 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.032849 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0327738 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0326829 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0316962 |
| FGG | fibrinogen gamma chain | 0.0314729 |
| RPL26 | ribosomal protein L26 | 0.030971 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0308581 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0306391 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0297955 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0297768 |
| FAM168A | family with sequence similarity 168, member A | 0.0293882 |
| MKI67 | marker of proliferation Ki-67 | 0.0293405 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0291255 |
| JAK1 | Janus kinase 1 | 0.0290157 |
| PFDN2 | prefoldin subunit 2 | 0.0286994 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.028403 |
| RRM2 | ribonucleotide reductase M2 | 0.0282801 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0275802 |
| USP3 | ubiquitin specific peptidase 3 | 0.0272892 |
| CANX | calnexin | 0.0272113 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0270026 |
| ECT2 | epithelial cell transforming 2 | 0.0269767 |
| RPS21 | ribosomal protein S21 | 0.0269349 |
| RPL3 | ribosomal protein L3 | 0.0269254 |
| EFNA5 | ephrin-A5 | 0.026687 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0265558 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0265465 |
| ANLN | anillin, actin binding protein | 0.0265429 |
| THBS1 | thrombospondin 1 | 0.0265424 |
| RPS27A | ribosomal protein S27a | 0.0263854 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0260203 |
| RPL41 | ribosomal protein L41 | 0.0247896 |
| FTL | ferritin, light polypeptide | 0.024513 |
| APP | amyloid beta (A4) precursor protein | 0.0244958 |
| RPS3 | ribosomal protein S3 | 0.024117 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0239551 |
| BICC1 | BicC family RNA binding protein 1 | 0.0238684 |
| ENAH | enabled homolog (Drosophila) | 0.0237569 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0236418 |
| OLA1 | Obg-like ATPase 1 | 0.0229495 |
| RPLP0 | ribosomal protein, large, P0 | 0.0228982 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0228383 |
| SET | SET nuclear proto-oncogene | 0.0228073 |
| AHNAK | AHNAK nucleoprotein | 0.0227016 |
| YBX1 | Y box binding protein 1 | 0.0226141 |
| SRGN | serglycin | 0.0225712 |
| HYOU1 | hypoxia up-regulated 1 | 0.0225128 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0224395 |
| TMEM123 | transmembrane protein 123 | 0.0223581 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0219628 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.195651 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.192566 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.140582 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.113957 |
| IGF2 | insulin-like growth factor 2 | -0.11297 |
| MT2A | metallothionein 2A | -0.105604 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0908321 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0871024 |
| FLNB | filamin B, beta | -0.0792752 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0786454 |
| FMNL2 | formin-like 2 | -0.0778044 |
| POTEF | POTE ankyrin domain family, member F | -0.076903 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0741974 |
| FNDC3B | fibronectin type III domain containing 3B | -0.073821 |
| PYGL | phosphorylase, glycogen, liver | -0.0737712 |
| CMIP | c-Maf inducing protein | -0.0715806 |
| NDRG1 | N-myc downstream regulated 1 | -0.0692707 |
| VIM | vimentin | -0.0679606 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0656497 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0653113 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0639124 |
| HLA-B | major histocompatibility complex, class I, B | -0.0615541 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0585283 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0550057 |
| COPA | coatomer protein complex, subunit alpha | -0.0533984 |
| EGFR | epidermal growth factor receptor | -0.0518117 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0483101 |
| HLA-A | major histocompatibility complex, class I, A | -0.0479 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0456788 |
| IL6 | interleukin 6 | -0.0456374 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0455071 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0452877 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0450089 |
| GOLGA4 | golgin A4 | -0.0419532 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0409316 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0399251 |
| GLG1 | golgi glycoprotein 1 | -0.0392487 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0392466 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0391968 |
| TMSB10 | thymosin beta 10 | -0.0389031 |
| RBM25 | RNA binding motif protein 25 | -0.0382913 |
| ACTG1 | actin gamma 1 | -0.0381013 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0380151 |
| ARF4 | ADP-ribosylation factor 4 | -0.0376608 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0374585 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0370605 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0360181 |
| MYO1E | myosin IE | -0.0351081 |
| HM13 | histocompatibility (minor) 13 | -0.0346894 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0340628 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0340376 |
| S100A6 | S100 calcium binding protein A6 | -0.033533 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0335175 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0330761 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0329715 |
| PARD3 | par-3 family cell polarity regulator | -0.0328156 |
| MORF4L2 | mortality factor 4 like 2 | -0.0326329 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0324881 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0323494 |
| NF1 | neurofibromin 1 | -0.0323359 |
| SRP54 | signal recognition particle 54kDa | -0.0318142 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0317039 |
| NUMB | numb homolog (Drosophila) | -0.0316539 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0314033 |
| IER3 | immediate early response 3 | -0.03136 |
| CTBP2 | C-terminal binding protein 2 | -0.0308056 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0302919 |
| SNX14 | sorting nexin 14 | -0.0298319 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0298167 |
| USP36 | ubiquitin specific peptidase 36 | -0.0295726 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.0294397 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0293278 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0293116 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0292046 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0290241 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0289963 |
| ACTN1 | actinin, alpha 1 | -0.0289864 |
| SLMAP | sarcolemma associated protein | -0.0285599 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0285039 |
| NEMF | nuclear export mediator factor | -0.0285028 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0283268 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0281627 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0278634 |
| MYADM | myeloid-associated differentiation marker | -0.0278076 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0278044 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0277494 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0274804 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0274642 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0273113 |
| LAMA5 | laminin, alpha 5 | -0.0266723 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0266342 |
| STC1 | stanniocalcin 1 | -0.0262953 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0261315 |
| ERBIN | erbb2 interacting protein | -0.0261058 |
| RNF216 | ring finger protein 216 | -0.026068 |
| SBF2 | SET binding factor 2 | -0.0260425 |
| MED13 | mediator complex subunit 13 | -0.0258146 |
| USP34 | ubiquitin specific peptidase 34 | -0.0257411 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0254836 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0254577 |
