| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.24805 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.203538 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.13393 |
| TPM3 | tropomyosin 3 | 0.0931972 |
| PTMA | prothymosin, alpha | 0.0883347 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0858255 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.079152 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.075414 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0718983 |
| GRAMD1B | GRAM domain containing 1B | 0.0698991 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0675762 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0673641 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0647437 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0619546 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0612705 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0579443 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0556619 |
| ENO1 | enolase 1, (alpha) | 0.0544591 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0543835 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0522878 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0507795 |
| TPI1 | triosephosphate isomerase 1 | 0.0499064 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0488391 |
| RPS8 | ribosomal protein S8 | 0.0475703 |
| YBX3 | Y box binding protein 3 | 0.0475101 |
| RPS12 | ribosomal protein S12 | 0.047167 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0467224 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0466838 |
| RPL37A | ribosomal protein L37a | 0.0465681 |
| SET | SET nuclear proto-oncogene | 0.0458338 |
| PRELID2 | PRELI domain containing 2 | 0.0445133 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0438608 |
| RPL4 | ribosomal protein L4 | 0.0436714 |
| RPS3 | ribosomal protein S3 | 0.0432875 |
| RPL26 | ribosomal protein L26 | 0.0428704 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0408861 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0402503 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0401027 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0395117 |
| DSPP | dentin sialophosphoprotein | 0.0391264 |
| XPO1 | exportin 1 | 0.0385369 |
| RPL41 | ribosomal protein L41 | 0.0380843 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0377005 |
| KRT18 | keratin 18, type I | 0.0375751 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0375562 |
| RPS2 | ribosomal protein S2 | 0.0374689 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0372851 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0371734 |
| RPL3 | ribosomal protein L3 | 0.0365625 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0364988 |
| RPS17 | ribosomal protein S17 | 0.0364148 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0360674 |
| CEP250 | centrosomal protein 250kDa | 0.0358318 |
| RPS27A | ribosomal protein S27a | 0.035016 |
| PLEC | plectin | 0.0349799 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.033881 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0338279 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0330639 |
| RPL23 | ribosomal protein L23 | 0.0326992 |
| MKI67 | marker of proliferation Ki-67 | 0.0324644 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | 0.031857 |
| PGK1 | phosphoglycerate kinase 1 | 0.0315959 |
| XPOT | exportin, tRNA | 0.0307457 |
| CTNNBL1 | catenin, beta like 1 | 0.0304936 |
| CTTN | cortactin | 0.0304704 |
| OGA | O-GlcNAcase | 0.0303603 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0302127 |
| PKM | pyruvate kinase, muscle | 0.0301257 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0301105 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0297208 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0296348 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.029262 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0290254 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0289015 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0287332 |
| CPNE1 | copine I | 0.0286206 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0285803 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.028555 |
| CENPF | centromere protein F, 350/400kDa | 0.0284823 |
| WWOX | WW domain containing oxidoreductase | 0.0281355 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0278671 |
| RPS29 | ribosomal protein S29 | 0.0278367 |
| DENR | density-regulated protein | 0.0277449 |
| IPO7 | importin 7 | 0.0275316 |
| MATR3 | matrin 3 | 0.027443 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0272944 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0270475 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0269352 |
| TRIM33 | tripartite motif containing 33 | 0.0268747 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0268267 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0267637 |
| RRM2 | ribonucleotide reductase M2 | 0.0267171 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0263733 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0262509 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0262446 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0261339 |
| NCKAP1 | NCK-associated protein 1 | 0.0261236 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0259711 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0258023 |
| PFDN2 | prefoldin subunit 2 | 0.0257968 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.19923 |
| EGR1 | early growth response 1 | -0.175224 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0738657 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0733953 |
| OSMR | oncostatin M receptor | -0.0727062 |
| NABP1 | nucleic acid binding protein 1 | -0.0689088 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0666446 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0576239 |
| RAD51B | RAD51 paralog B | -0.0540176 |
| TXNRD1 | thioredoxin reductase 1 | -0.0523446 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0500676 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0495064 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0462684 |
| NF1 | neurofibromin 1 | -0.0444684 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0431511 |
| COPA | coatomer protein complex, subunit alpha | -0.0429226 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0426612 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0419641 |
| POTEF | POTE ankyrin domain family, member F | -0.0413459 |
| EGFR | epidermal growth factor receptor | -0.0403448 |
| IGF2 | insulin-like growth factor 2 | -0.0401362 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0392941 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0380853 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0375356 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0374474 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0364648 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0352276 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0350793 |
| HMGA1 | high mobility group AT-hook 1 | -0.0347937 |
| CCNL1 | cyclin L1 | -0.0345074 |
| USP34 | ubiquitin specific peptidase 34 | -0.0339594 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0327632 |
| VCL | vinculin | -0.032444 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0322345 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0320961 |
| MEF2D | myocyte enhancer factor 2D | -0.0317749 |
| WASF2 | WAS protein family, member 2 | -0.031653 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0312543 |
| JMJD1C | jumonji domain containing 1C | -0.0303808 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0297669 |
| WDR70 | WD repeat domain 70 | -0.0292374 |
| TAPBP | TAP binding protein (tapasin) | -0.0284276 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0280272 |
| HDAC8 | histone deacetylase 8 | -0.0274886 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0274175 |
| ARF4 | ADP-ribosylation factor 4 | -0.0271307 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0270961 |
| ATN1 | atrophin 1 | -0.0268531 |
| NBEAL1 | neurobeachin-like 1 | -0.0264918 |
| BSG | basigin (Ok blood group) | -0.0263075 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0262958 |
| GATAD2B | GATA zinc finger domain containing 2B | -0.0259461 |
| HMGA2 | high mobility group AT-hook 2 | -0.0257823 |
| ATF6 | activating transcription factor 6 | -0.0252646 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0252357 |
| FTL | ferritin, light polypeptide | -0.0251442 |
| DHFR | dihydrofolate reductase | -0.0251016 |
| VMP1 | vacuole membrane protein 1 | -0.0248563 |
| LATS2 | large tumor suppressor kinase 2 | -0.0242503 |
| MMP12 | matrix metallopeptidase 12 | -0.0242416 |
| ZMYM4 | zinc finger, MYM-type 4 | -0.0239922 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0234821 |
| BPTF | bromodomain PHD finger transcription factor | -0.023469 |
| RSF1 | remodeling and spacing factor 1 | -0.0232394 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0231022 |
| TAOK1 | TAO kinase 1 | -0.023077 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0227623 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0227447 |
| PPP4R3B | protein phosphatase 4 regulatory subunit 3B | -0.02254 |
| CDK17 | cyclin-dependent kinase 17 | -0.022456 |
| SBF2 | SET binding factor 2 | -0.0224209 |
| BRD2 | bromodomain containing 2 | -0.0223687 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0223627 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0221475 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0221139 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0218205 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0218188 |
| ZNF644 | zinc finger protein 644 | -0.021738 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0216277 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0214675 |
| SETD5 | SET domain containing 5 | -0.0214456 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0213478 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0213227 |
| NTSR1 | neurotensin receptor 1 (high affinity) | -0.021132 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0211296 |
| MYADM | myeloid-associated differentiation marker | -0.020698 |
| HDAC9 | histone deacetylase 9 | -0.0206722 |
| FCHSD2 | FCH and double SH3 domains 2 | -0.0206218 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0206216 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0203996 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0203785 |
| MBTD1 | mbt domain containing 1 | -0.0203772 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0203462 |
| FBXO11 | F-box protein 11 | -0.0202622 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0200271 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0199078 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0198294 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0197035 |
| GPATCH8 | G patch domain containing 8 | -0.0197034 |
| ZNF609 | zinc finger protein 609 | -0.0194901 |
