| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.174748 |
| PLEC | plectin | 0.140326 |
| MT2A | metallothionein 2A | 0.109623 |
| LAMB3 | laminin, beta 3 | 0.104509 |
| CALR | calreticulin | 0.0794542 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0766332 |
| ACTG1 | actin gamma 1 | 0.0758587 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0734932 |
| RPL4 | ribosomal protein L4 | 0.0633173 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0629753 |
| TOP1 | topoisomerase (DNA) I | 0.0628981 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0609114 |
| AHNAK | AHNAK nucleoprotein | 0.0571285 |
| RPL23 | ribosomal protein L23 | 0.054274 |
| TMSB4X | thymosin beta 4, X-linked | 0.0537877 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0533695 |
| RPL3 | ribosomal protein L3 | 0.0533134 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0513587 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0508889 |
| DSPP | dentin sialophosphoprotein | 0.0498082 |
| RACK1 | receptor for activated C kinase 1 | 0.0492898 |
| FN1 | fibronectin 1 | 0.0486172 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0459161 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0457494 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0443873 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0441804 |
| KRT8 | keratin 8, type II | 0.0434422 |
| HOMER2 | homer scaffolding protein 2 | 0.0428025 |
| G0S2 | G0/G1 switch 2 | 0.041355 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0413377 |
| KRT7 | keratin 7, type II | 0.040704 |
| KRT18 | keratin 18, type I | 0.0397831 |
| RPS3 | ribosomal protein S3 | 0.0386386 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0384088 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0381371 |
| TPI1 | triosephosphate isomerase 1 | 0.0372004 |
| PGK1 | phosphoglycerate kinase 1 | 0.0367981 |
| AREG | amphiregulin | 0.0354018 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.035218 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0352021 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0338161 |
| FLNA | filamin A, alpha | 0.0329446 |
| MSN | moesin | 0.0327522 |
| ENO1 | enolase 1, (alpha) | 0.0307039 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0298297 |
| RPSA | ribosomal protein SA | 0.0296356 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.029629 |
| VEGFA | vascular endothelial growth factor A | 0.0287232 |
| HDGF | hepatoma-derived growth factor | 0.027916 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0277008 |
| NUP58 | nucleoporin 58 | 0.0274215 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0271375 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.027079 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0270635 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0270475 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0268123 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0260949 |
| SET | SET nuclear proto-oncogene | 0.0260731 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0257867 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0256831 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0254021 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0249481 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0247678 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.024625 |
| UPP1 | uridine phosphorylase 1 | 0.0241244 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0241232 |
| RPS12 | ribosomal protein S12 | 0.0239314 |
| PKM | pyruvate kinase, muscle | 0.0237195 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0236238 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0236014 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0227006 |
| TPM3 | tropomyosin 3 | 0.0225348 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0223165 |
| TUBB | tubulin, beta class I | 0.0223144 |
| RPS17 | ribosomal protein S17 | 0.0222319 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0220101 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0216751 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0214425 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0213129 |
| YBX1 | Y box binding protein 1 | 0.0212384 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0210714 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0210653 |
| EREG | epiregulin | 0.020863 |
| RNF145 | ring finger protein 145 | 0.0208158 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0207185 |
| NCKAP1 | NCK-associated protein 1 | 0.0206488 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0206222 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0204025 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0200724 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0199906 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0199545 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0198263 |
| PFKP | phosphofructokinase, platelet | 0.0197631 |
| XPOT | exportin, tRNA | 0.0196422 |
| FLNB | filamin B, beta | 0.0192169 |
| CCNY | cyclin Y | 0.0190269 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0188935 |
| FMNL2 | formin-like 2 | 0.0188754 |
| KLF6 | Kruppel-like factor 6 | 0.0188319 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0186943 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.21381 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.190503 |
| NDRG1 | N-myc downstream regulated 1 | -0.125474 |
| MYO6 | myosin VI | -0.100366 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0881047 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0869419 |
| HMGA1 | high mobility group AT-hook 1 | -0.0811967 |
| FTL | ferritin, light polypeptide | -0.0806614 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0801589 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0754055 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0700376 |
| LMO7 | LIM domain 7 | -0.0695784 |
| RAB7A | RAB7A, member RAS oncogene family | -0.068929 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.062222 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0615256 |
| FBXO32 | F-box protein 32 | -0.0603617 |
| ERBIN | erbb2 interacting protein | -0.0601997 |
| POTEF | POTE ankyrin domain family, member F | -0.0586923 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0574851 |
| ASPH | aspartate beta-hydroxylase | -0.056634 |
| CD2AP | CD2-associated protein | -0.054544 |
| DTNA | dystrobrevin, alpha | -0.0535176 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0511686 |
| DSG2 | desmoglein 2 | -0.050906 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0497114 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.049288 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0484274 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.04827 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0475005 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0467583 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0458488 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0457913 |
| GOLGA4 | golgin A4 | -0.0457088 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0452087 |
| PTMA | prothymosin, alpha | -0.0447566 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0423697 |
| JMJD1C | jumonji domain containing 1C | -0.0423432 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0421156 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.041762 |
| RBM39 | RNA binding motif protein 39 | -0.0415895 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0412127 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0411 |
| MYO1E | myosin IE | -0.0406656 |
| TXNIP | thioredoxin interacting protein | -0.0403052 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0402848 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0400974 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0392611 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0390945 |
| SPAG9 | sperm associated antigen 9 | -0.039061 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0389491 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.038877 |
| ANXA2 | annexin A2 | -0.0385399 |
| TMEM263 | transmembrane protein 263 | -0.0383556 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0382256 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.037494 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0374675 |
| FBXO11 | F-box protein 11 | -0.0371577 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0361593 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0354186 |
| MCU | mitochondrial calcium uniporter | -0.0353025 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.0351604 |
| RCOR1 | REST corepressor 1 | -0.0346736 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0342193 |
| SVIL | supervillin | -0.0341615 |
| MED13 | mediator complex subunit 13 | -0.0341072 |
| RBM47 | RNA binding motif protein 47 | -0.033903 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0336973 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0336303 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | -0.0331705 |
| PTK2 | protein tyrosine kinase 2 | -0.0327703 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0326511 |
| FNIP1 | folliculin interacting protein 1 | -0.032428 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0320907 |
| AFF4 | AF4/FMR2 family, member 4 | -0.032018 |
| ZNF292 | zinc finger protein 292 | -0.0318686 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.031719 |
| BBX | bobby sox homolog (Drosophila) | -0.0315443 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0313892 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0313357 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0312579 |
| GOLGB1 | golgin B1 | -0.0310285 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0309729 |
| SEPTIN11 | septin 11 | -0.0309685 |
| RLF | rearranged L-myc fusion | -0.0306725 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0306647 |
| EPCAM | epithelial cell adhesion molecule | -0.0305662 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0304259 |
| PLSCR1 | phospholipid scramblase 1 | -0.0303812 |
| UBC | ubiquitin C | -0.0303191 |
| TMF1 | TATA element modulatory factor 1 | -0.0302899 |
| CLDN4 | claudin 4 | -0.0302111 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0300383 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0299046 |
| MXD1 | MAX dimerization protein 1 | -0.0297696 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0295497 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0293729 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0293427 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0292822 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0291627 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0291108 |
