| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.168598 |
| RPS16 | ribosomal protein S16 | 0.1315 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.129623 |
| EGFR | epidermal growth factor receptor | 0.126119 |
| PCBP2 | poly(rC) binding protein 2 | 0.109416 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.109278 |
| PTMA | prothymosin, alpha | 0.105575 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.103066 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.101504 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0886519 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0866083 |
| STC1 | stanniocalcin 1 | 0.0865043 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0863525 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.083169 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0831585 |
| PARD3 | par-3 family cell polarity regulator | 0.0822532 |
| RPS24 | ribosomal protein S24 | 0.0813826 |
| RACK1 | receptor for activated C kinase 1 | 0.07953 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0775776 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0773453 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0717682 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0713458 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0692603 |
| ANXA2 | annexin A2 | 0.0690779 |
| FAM162A | family with sequence similarity 162, member A | 0.067187 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0660425 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0597304 |
| RPS8 | ribosomal protein S8 | 0.0592677 |
| RPS6 | ribosomal protein S6 | 0.0585936 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0535301 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0527924 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0527414 |
| MCL1 | myeloid cell leukemia 1 | 0.0507941 |
| EXOC4 | exocyst complex component 4 | 0.0503378 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.049409 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0490358 |
| B2M | beta-2-microglobulin | 0.0481582 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0472289 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0471955 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0471876 |
| OGA | O-GlcNAcase | 0.0465135 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0462997 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0457951 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0454842 |
| NEK7 | NIMA-related kinase 7 | 0.0445309 |
| RPS3 | ribosomal protein S3 | 0.0440331 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0433717 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0432303 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0427732 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0425637 |
| TMEM123 | transmembrane protein 123 | 0.0424222 |
| ZNF292 | zinc finger protein 292 | 0.0418821 |
| ZNF638 | zinc finger protein 638 | 0.0405612 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0382098 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0380026 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0358997 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0352717 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0351275 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.035065 |
| RNF145 | ring finger protein 145 | 0.0345815 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0343953 |
| SPAG9 | sperm associated antigen 9 | 0.0341702 |
| HLA-B | major histocompatibility complex, class I, B | 0.0336569 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0330054 |
| RBM39 | RNA binding motif protein 39 | 0.0327851 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0327387 |
| TMEM165 | transmembrane protein 165 | 0.0321822 |
| RPS12 | ribosomal protein S12 | 0.0312718 |
| LDHA | lactate dehydrogenase A | 0.0311449 |
| FTL | ferritin, light polypeptide | 0.0289262 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0285522 |
| RPLP1 | ribosomal protein, large, P1 | 0.0282502 |
| EGR1 | early growth response 1 | 0.027483 |
| USP34 | ubiquitin specific peptidase 34 | 0.0268003 |
| RTN4 | reticulon 4 | 0.0266452 |
| SLTM | SAFB-like, transcription modulator | 0.0250321 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0205189 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0202128 |
| CD2AP | CD2-associated protein | 0.0192403 |
| VMP1 | vacuole membrane protein 1 | 0.0190281 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0176817 |
| MYOF | myoferlin | 0.0176112 |
| SBF2 | SET binding factor 2 | 0.0171911 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0162449 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0158095 |
| ARRDC3 | arrestin domain containing 3 | 0.0155772 |
| ERBIN | erbb2 interacting protein | 0.0154667 |
| TXNRD1 | thioredoxin reductase 1 | 0.0116502 |
| MYO6 | myosin VI | 0.0111957 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.011106 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0106534 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0104666 |
| ZNF148 | zinc finger protein 148 | 0.00975946 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00745171 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.00709705 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0070194 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.00688771 |
| MT2A | metallothionein 2A | 0.00657067 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.00561332 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.00522232 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.210755 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.127613 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.102027 |
| LMO7 | LIM domain 7 | -0.0934416 |
| MED13 | mediator complex subunit 13 | -0.0926239 |
| GOLGA4 | golgin A4 | -0.0868095 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0809158 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0788005 |
| SMYD3 | SET and MYND domain containing 3 | -0.0777225 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0774198 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0762724 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0740518 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0734411 |
| ASPH | aspartate beta-hydroxylase | -0.0726554 |
| FN1 | fibronectin 1 | -0.0714283 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0671856 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0667431 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.064711 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0629544 |
| PRKCA | protein kinase C, alpha | -0.0623643 |
| TNS3 | tensin 3 | -0.0623479 |
| RPL35A | ribosomal protein L35a | -0.0609059 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0594716 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0577047 |
| GRAMD1B | GRAM domain containing 1B | -0.0575529 |
| PKM | pyruvate kinase, muscle | -0.0567948 |
| HMGA2 | high mobility group AT-hook 2 | -0.0544132 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0529166 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0527266 |
| ACTG1 | actin gamma 1 | -0.0512599 |
| FNIP1 | folliculin interacting protein 1 | -0.0507033 |
| VCL | vinculin | -0.0503611 |
| JMJD1C | jumonji domain containing 1C | -0.0498263 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.049172 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0483245 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0480936 |
| EZR | ezrin | -0.0450479 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0438446 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0427864 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0427678 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0425268 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0422328 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0418472 |
| NAV2 | neuron navigator 2 | -0.0417675 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0415648 |
| FLNB | filamin B, beta | -0.0406742 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0397532 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0395129 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0384183 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0379127 |
| GPC6 | glypican 6 | -0.0366725 |
| DST | dystonin | -0.0351766 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0337317 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0321983 |
| AHNAK | AHNAK nucleoprotein | -0.0309933 |
| PDE8A | phosphodiesterase 8A | -0.0308864 |
| TPM4 | tropomyosin 4 | -0.030685 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0301368 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.029287 |
| PTK2 | protein tyrosine kinase 2 | -0.0289224 |
| CDH13 | cadherin 13 | -0.0288708 |
| LAMA4 | laminin, alpha 4 | -0.026036 |
| HDAC9 | histone deacetylase 9 | -0.0252528 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0250492 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0250315 |
| NDRG1 | N-myc downstream regulated 1 | -0.0247636 |
| FMN1 | formin 1 | -0.0243804 |
| MYO1E | myosin IE | -0.0227361 |
| MAP4 | microtubule-associated protein 4 | -0.0222469 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0217673 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0213074 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0206714 |
| ATXN1 | ataxin 1 | -0.0202708 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0187233 |
| YBX3 | Y box binding protein 3 | -0.0178493 |
| CTBP2 | C-terminal binding protein 2 | -0.0178184 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0168749 |
| SETD5 | SET domain containing 5 | -0.0165421 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0163601 |
| VIM | vimentin | -0.0163273 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0163248 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0155366 |
| POTEF | POTE ankyrin domain family, member F | -0.0153871 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0150675 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.014611 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0134278 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0130529 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0125382 |
| RPL31 | ribosomal protein L31 | -0.0116536 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0112106 |
| TFG | TRK-fused gene | -0.00835146 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.00642719 |
| FMNL2 | formin-like 2 | -0.0051489 |
| TMSB10 | thymosin beta 10 | -0.00512451 |
| RUNX1 | runt-related transcription factor 1 | -0.00496416 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.00452109 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.00385793 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00354632 |
| PGK1 | phosphoglycerate kinase 1 | -0.00350056 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.00313315 |
