| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.223432 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.121231 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0785109 |
| SEPTIN9 | septin 9 | 0.0768251 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0582541 |
| PLEC | plectin | 0.0519999 |
| SMAD3 | SMAD family member 3 | 0.0481782 |
| PRELID2 | PRELI domain containing 2 | 0.0425222 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0397326 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0397292 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0394022 |
| AFAP1 | actin filament associated protein 1 | 0.0384088 |
| RPL3 | ribosomal protein L3 | 0.0348648 |
| ANGPTL4 | angiopoietin-like 4 | 0.0343049 |
| DST | dystonin | 0.0328041 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0288106 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0281667 |
| MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 0.028136 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0279567 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0266873 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.026674 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0266595 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.026499 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.026392 |
| AHNAK | AHNAK nucleoprotein | 0.0259711 |
| ACTN4 | actinin, alpha 4 | 0.0250929 |
| AFDN | afadin, adherens junction formation factor | 0.024814 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0243948 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0226117 |
| RPS12 | ribosomal protein S12 | 0.0225086 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.022403 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0219528 |
| CDK19 | cyclin-dependent kinase 19 | 0.0217883 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0208768 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.020769 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0202122 |
| YEATS2 | YEATS domain containing 2 | 0.0200421 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0195673 |
| RPL4 | ribosomal protein L4 | 0.0193857 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0193766 |
| HOXB3 | homeobox B3 | 0.0193281 |
| ANLN | anillin, actin binding protein | 0.0193019 |
| CACNG8 | calcium channel, voltage-dependent, gamma subunit 8 | 0.0186815 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0185265 |
| LMNA | lamin A/C | 0.0185105 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0181822 |
| FLNA | filamin A, alpha | 0.0181561 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.017577 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0173473 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.0170276 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0169901 |
| CEP250 | centrosomal protein 250kDa | 0.0167844 |
| SET | SET nuclear proto-oncogene | 0.016354 |
| RPS2 | ribosomal protein S2 | 0.0162689 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0161583 |
| H1-4 | H1.4 linker histone, cluster member | 0.0160062 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0158985 |
| ZNF292 | zinc finger protein 292 | 0.0157791 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0156518 |
| HOXB6 | homeobox B6 | 0.0154278 |
| ATXN1 | ataxin 1 | 0.0152176 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0151259 |
| RPS3 | ribosomal protein S3 | 0.0151085 |
| SMYD3 | SET and MYND domain containing 3 | 0.0151039 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.015075 |
| DNMBP | dynamin binding protein | 0.0147279 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0145341 |
| ATG10 | autophagy related 10 | 0.0143287 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0143093 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0142894 |
| CALR | calreticulin | 0.0141033 |
| FLOT1 | flotillin 1 | 0.0139401 |
| NFIA | nuclear factor I/A | 0.0139174 |
| RPS17 | ribosomal protein S17 | 0.0138236 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0137828 |
| ZNF146 | zinc finger protein 146 | 0.0136946 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.013681 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0135675 |
| ANKRD36C | ankyrin repeat domain 36C | 0.013473 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.0134217 |
| UCK2 | uridine-cytidine kinase 2 | 0.013398 |
| ZNF780A | zinc finger protein 780A | 0.0133433 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0133304 |
| ZNF638 | zinc finger protein 638 | 0.0132915 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0132449 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0132322 |
| CTTN | cortactin | 0.013176 |
| SLK | STE20-like kinase | 0.0131555 |
| XPOT | exportin, tRNA | 0.0131302 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0131028 |
| TMSB4X | thymosin beta 4, X-linked | 0.0130418 |
| RPS15A | ribosomal protein S15a | 0.0130377 |
| ZNF780B | zinc finger protein 780B | 0.0130155 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0129622 |
| MYOF | myoferlin | 0.0129026 |
| RPL26 | ribosomal protein L26 | 0.0128573 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0128067 |
| FLNB | filamin B, beta | 0.0127558 |
| CEP70 | centrosomal protein 70kDa | 0.0127469 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0127239 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.300744 |
| VIM | vimentin | -0.237336 |
| VCL | vinculin | -0.167301 |
| RPS16 | ribosomal protein S16 | -0.151076 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.083098 |
| PTMA | prothymosin, alpha | -0.0798006 |
| ZFP36 | ZFP36 ring finger protein | -0.0746213 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0745296 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0743205 |
| CD44 | CD44 molecule (Indian blood group) | -0.0630986 |
| ANXA2 | annexin A2 | -0.059503 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0593136 |
| TMEM123 | transmembrane protein 123 | -0.0546591 |
| S100A6 | S100 calcium binding protein A6 | -0.0540923 |
| FTL | ferritin, light polypeptide | -0.0537795 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0531656 |
| EGR1 | early growth response 1 | -0.0501901 |
| HMGA1 | high mobility group AT-hook 1 | -0.0501159 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0486532 |
| FBL | fibrillarin | -0.0482485 |
| RPLP0 | ribosomal protein, large, P0 | -0.0477738 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0468477 |
| TMSB10 | thymosin beta 10 | -0.0466816 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0455426 |
| MORF4L2 | mortality factor 4 like 2 | -0.0452263 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0433108 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.042994 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0421438 |
| LDHA | lactate dehydrogenase A | -0.0411856 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0400034 |
| MAP1B | microtubule-associated protein 1B | -0.0393365 |
| UBC | ubiquitin C | -0.0384287 |
| JMJD1C | jumonji domain containing 1C | -0.0352522 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0347291 |
| CTSD | cathepsin D | -0.0344249 |
| PFN1 | profilin 1 | -0.0343197 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0333375 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0327812 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.032213 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0311658 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0309576 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0302943 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0293924 |
| YBX1 | Y box binding protein 1 | -0.02931 |
| POTEF | POTE ankyrin domain family, member F | -0.0289893 |
| ITGAV | integrin, alpha V | -0.0289433 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0285271 |
| WASF2 | WAS protein family, member 2 | -0.0275649 |
| NF1 | neurofibromin 1 | -0.0275374 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0275033 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0274822 |
| CANX | calnexin | -0.0269466 |
| RTN4 | reticulon 4 | -0.0267815 |
| UBAP2 | ubiquitin associated protein 2 | -0.0264673 |
| H1-0 | H1.0 linker histone | -0.0263311 |
| MYO1E | myosin IE | -0.0262466 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0257959 |
| ZNF644 | zinc finger protein 644 | -0.0249581 |
| RPL27A | ribosomal protein L27a | -0.0240871 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0238559 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0237574 |
| TPM1 | tropomyosin 1 (alpha) | -0.0235256 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0232884 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.023286 |
| ERBIN | erbb2 interacting protein | -0.0230779 |
| MED29 | mediator complex subunit 29 | -0.0230214 |
| PERP | PERP, TP53 apoptosis effector | -0.0229895 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0227671 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0227204 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0223938 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0222521 |
| MYADM | myeloid-associated differentiation marker | -0.0220355 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0219557 |
| FNDC3B | fibronectin type III domain containing 3B | -0.021899 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0211835 |
| NUP98 | nucleoporin 98kDa | -0.0211708 |
| RASAL2 | RAS protein activator like 2 | -0.0211366 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0210241 |
| RPS24 | ribosomal protein S24 | -0.0209532 |
| CCND1 | cyclin D1 | -0.0208121 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0205969 |
| SQSTM1 | sequestosome 1 | -0.0201242 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0200545 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0200028 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.019977 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0199332 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0196927 |
| INTS6 | integrator complex subunit 6 | -0.0196762 |
| CD109 | CD109 molecule | -0.0195253 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0192149 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0191973 |
| DSTN | destrin (actin depolymerizing factor) | -0.0191456 |
| ACTG1 | actin gamma 1 | -0.0191184 |
| TAOK1 | TAO kinase 1 | -0.0191109 |
| TUBA1B | tubulin, alpha 1b | -0.0190441 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0190363 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0190114 |
| S100A10 | S100 calcium binding protein A10 | -0.0188485 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0187713 |
| BSG | basigin (Ok blood group) | -0.0187279 |
