| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.107604 |
| FAM3C | family with sequence similarity 3, member C | 0.0996616 |
| LAMB3 | laminin, beta 3 | 0.0993368 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.09436 |
| TMSB4X | thymosin beta 4, X-linked | 0.0783918 |
| MYO6 | myosin VI | 0.0713727 |
| KRT17 | keratin 17, type I | 0.070282 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0698939 |
| CALR | calreticulin | 0.0685554 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0681181 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0675062 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0661267 |
| DSPP | dentin sialophosphoprotein | 0.0660843 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0654557 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0648743 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0589971 |
| PTMA | prothymosin, alpha | 0.0583163 |
| KRT18 | keratin 18, type I | 0.055972 |
| ANLN | anillin, actin binding protein | 0.0548367 |
| OGA | O-GlcNAcase | 0.054127 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0527364 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0525631 |
| XPO1 | exportin 1 | 0.0524507 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0513658 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.050709 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.049333 |
| EZR | ezrin | 0.0480615 |
| AHNAK | AHNAK nucleoprotein | 0.0468225 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0465135 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0460999 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0458781 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0432785 |
| PLEC | plectin | 0.0431133 |
| ARRDC3 | arrestin domain containing 3 | 0.0430225 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0424663 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0419196 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0410232 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0408862 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0399421 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0398786 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0394627 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.039068 |
| JMJD1C | jumonji domain containing 1C | 0.0388976 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0388786 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0387432 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0383853 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0380544 |
| MKI67 | marker of proliferation Ki-67 | 0.0372669 |
| RIOK3 | RIO kinase 3 | 0.0369653 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0368422 |
| TMF1 | TATA element modulatory factor 1 | 0.0364777 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0363208 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0361652 |
| ATP13A3 | ATPase type 13A3 | 0.0352306 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0349667 |
| LAMC2 | laminin, gamma 2 | 0.0349223 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0348245 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0346272 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0345771 |
| GOLGA4 | golgin A4 | 0.0340813 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0340168 |
| RAB6A | RAB6A, member RAS oncogene family | 0.033872 |
| TOP1 | topoisomerase (DNA) I | 0.0337717 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0337422 |
| RAD21 | RAD21 homolog (S. pombe) | 0.033363 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0331135 |
| PGK1 | phosphoglycerate kinase 1 | 0.0327986 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0321526 |
| NCKAP1 | NCK-associated protein 1 | 0.0319102 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0318815 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0307571 |
| TPR | translocated promoter region, nuclear basket protein | 0.0304878 |
| SPAG9 | sperm associated antigen 9 | 0.0301765 |
| TFG | TRK-fused gene | 0.0301716 |
| HMGB2 | high mobility group box 2 | 0.0300736 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0298279 |
| H1-4 | H1.4 linker histone, cluster member | 0.0297739 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0291021 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0290582 |
| CENPF | centromere protein F, 350/400kDa | 0.0290047 |
| RPL3 | ribosomal protein L3 | 0.0289628 |
| ECT2 | epithelial cell transforming 2 | 0.0283021 |
| CCNY | cyclin Y | 0.0282884 |
| TPM3 | tropomyosin 3 | 0.0282014 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0280797 |
| MTAP | methylthioadenosine phosphorylase | 0.0279132 |
| CANX | calnexin | 0.0278543 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0272645 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.026911 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0264905 |
| PLAT | plasminogen activator, tissue | 0.0264734 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0264233 |
| KIF5B | kinesin family member 5B | 0.0262673 |
| OPTN | optineurin | 0.0258909 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0257501 |
| CD2AP | CD2-associated protein | 0.025697 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0256319 |
| NAV2 | neuron navigator 2 | 0.0255285 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0254001 |
| RNF149 | ring finger protein 149 | 0.0251852 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.362246 |
| INTS6 | integrator complex subunit 6 | -0.109495 |
| HMGA1 | high mobility group AT-hook 1 | -0.099095 |
| MT2A | metallothionein 2A | -0.0989099 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0955916 |
| ACTG1 | actin gamma 1 | -0.0876963 |
| POTEF | POTE ankyrin domain family, member F | -0.0803307 |
| FN1 | fibronectin 1 | -0.0797618 |
| RPLP1 | ribosomal protein, large, P1 | -0.0794222 |
| RPS6 | ribosomal protein S6 | -0.078239 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0779441 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0776252 |
| LMO7 | LIM domain 7 | -0.0773896 |
| TMSB10 | thymosin beta 10 | -0.0768716 |
| RPL35A | ribosomal protein L35a | -0.0760289 |
| EGR1 | early growth response 1 | -0.0745562 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0657175 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0656065 |
| RPS19 | ribosomal protein S19 | -0.0652679 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0648562 |
| SVIL | supervillin | -0.0636669 |
| PLSCR1 | phospholipid scramblase 1 | -0.0610948 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0602252 |
| FTL | ferritin, light polypeptide | -0.0586661 |
| RPL28 | ribosomal protein L28 | -0.0562648 |
| MUC16 | mucin 16, cell surface associated | -0.0541269 |
| CD44 | CD44 molecule (Indian blood group) | -0.0539162 |
| RNF213 | ring finger protein 213 | -0.0523585 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0523218 |
| RPL23 | ribosomal protein L23 | -0.0516689 |
| TJP1 | tight junction protein 1 | -0.0500069 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.04998 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0488546 |
| RPS8 | ribosomal protein S8 | -0.0470653 |
| HLA-B | major histocompatibility complex, class I, B | -0.0468624 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0454311 |
| RPL31 | ribosomal protein L31 | -0.0442832 |
| ANXA2 | annexin A2 | -0.0434164 |
| SQSTM1 | sequestosome 1 | -0.0432551 |
| MYO1E | myosin IE | -0.0426903 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0418051 |
| RPLP2 | ribosomal protein, large, P2 | -0.0415094 |
| MUC4 | mucin 4, cell surface associated | -0.0411219 |
| RPL34 | ribosomal protein L34 | -0.0408988 |
| RIGI | RNA sensor RIG-I | -0.0407033 |
| RPL19 | ribosomal protein L19 | -0.0406644 |
| RPS23 | ribosomal protein S23 | -0.040649 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0405957 |
| RPS13 | ribosomal protein S13 | -0.040228 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0399533 |
| MX2 | MX dynamin-like GTPase 2 | -0.0399355 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0397396 |
| CLDN4 | claudin 4 | -0.0395228 |
| SP100 | SP100 nuclear antigen | -0.0394152 |
| TAPBP | TAP binding protein (tapasin) | -0.038668 |
| SYT14 | synaptotagmin XIV | -0.0382441 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0376917 |
| RPS29 | ribosomal protein S29 | -0.0376858 |
| HDAC9 | histone deacetylase 9 | -0.0369967 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0369563 |
| RASAL2 | RAS protein activator like 2 | -0.0367682 |
| RPS15 | ribosomal protein S15 | -0.0360726 |
| HMGA2 | high mobility group AT-hook 2 | -0.0354986 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0353815 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0351189 |
| RPL36 | ribosomal protein L36 | -0.0346906 |
| RPS24 | ribosomal protein S24 | -0.034059 |
| RPS14 | ribosomal protein S14 | -0.033677 |
| MX1 | MX dynamin-like GTPase 1 | -0.0336721 |
| IFI44L | interferon-induced protein 44-like | -0.0335202 |
| CCND1 | cyclin D1 | -0.0333511 |
| LAMA4 | laminin, alpha 4 | -0.0333351 |
| RPS21 | ribosomal protein S21 | -0.0331095 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0329158 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0317427 |
| HLA-A | major histocompatibility complex, class I, A | -0.0313667 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0312234 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0306238 |
| RPL37A | ribosomal protein L37a | -0.0301926 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | -0.0296593 |
| HLA-C | major histocompatibility complex, class I, C | -0.0289904 |
| RPS25 | ribosomal protein S25 | -0.028921 |
| RPL11 | ribosomal protein L11 | -0.0286072 |
| RAD51B | RAD51 paralog B | -0.02837 |
| RPL38 | ribosomal protein L38 | -0.0283652 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0283183 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0281424 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0280504 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0276795 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0275142 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0274775 |
| TLE4 | transducin-like enhancer of split 4 | -0.0274529 |
| S100A9 | S100 calcium binding protein A9 | -0.0270845 |
| RPL12 | ribosomal protein L12 | -0.0270752 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0269796 |
| RPS5 | ribosomal protein S5 | -0.0267595 |
| RPS16 | ribosomal protein S16 | -0.0267494 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0258249 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0255483 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0252591 |
