| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.220065 |
| MT2A | metallothionein 2A | 0.0847959 |
| NDRG1 | N-myc downstream regulated 1 | 0.0780842 |
| MSN | moesin | 0.0769981 |
| VEGFA | vascular endothelial growth factor A | 0.0693233 |
| ANGPTL4 | angiopoietin-like 4 | 0.069089 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0560989 |
| COL5A1 | collagen, type V, alpha 1 | 0.0553928 |
| PLEC | plectin | 0.0548527 |
| PKM | pyruvate kinase, muscle | 0.0522605 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0514516 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0468514 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0441916 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0441741 |
| YEATS2 | YEATS domain containing 2 | 0.0434454 |
| PFKP | phosphofructokinase, platelet | 0.0418059 |
| B2M | beta-2-microglobulin | 0.0416516 |
| CALR | calreticulin | 0.039459 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0389958 |
| LMNA | lamin A/C | 0.0370519 |
| FLNB | filamin B, beta | 0.035734 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.035121 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0350194 |
| AFAP1 | actin filament associated protein 1 | 0.0346249 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0341379 |
| RPL3 | ribosomal protein L3 | 0.0338103 |
| FAM13A | family with sequence similarity 13, member A | 0.0333839 |
| MCL1 | myeloid cell leukemia 1 | 0.0329453 |
| PGK1 | phosphoglycerate kinase 1 | 0.0323985 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0321741 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.03209 |
| TGM2 | transglutaminase 2 | 0.031259 |
| CD109 | CD109 molecule | 0.0309944 |
| CEP250 | centrosomal protein 250kDa | 0.0306384 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0305236 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0300009 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0294964 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0291587 |
| GYS1 | glycogen synthase 1 (muscle) | 0.028651 |
| MLPH | melanophilin | 0.0285264 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0284838 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0280786 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0279085 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0273974 |
| FLNA | filamin A, alpha | 0.0272903 |
| IFI44 | interferon-induced protein 44 | 0.0269975 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0265073 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0262003 |
| FNDC3B | fibronectin type III domain containing 3B | 0.025992 |
| XPO1 | exportin 1 | 0.0259064 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0252657 |
| CDK19 | cyclin-dependent kinase 19 | 0.025039 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0248268 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0244157 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0242974 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0241986 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0241492 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0237562 |
| MYO1B | myosin IB | 0.0236899 |
| RPS17 | ribosomal protein S17 | 0.0234643 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0233199 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0231657 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0227964 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0222978 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0219569 |
| ASPH | aspartate beta-hydroxylase | 0.021862 |
| C1D | C1D nuclear receptor corepressor | 0.0218053 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.021699 |
| COPA | coatomer protein complex, subunit alpha | 0.0215474 |
| COL13A1 | collagen, type XIII, alpha 1 | 0.0213316 |
| RPS12 | ribosomal protein S12 | 0.0207698 |
| PARVB | parvin, beta | 0.0207459 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0205979 |
| SET | SET nuclear proto-oncogene | 0.0205584 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0202587 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0201533 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0201221 |
| AFDN | afadin, adherens junction formation factor | 0.0200813 |
| INSIG2 | insulin induced gene 2 | 0.020011 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0197743 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0195678 |
| ZNF160 | zinc finger protein 160 | 0.0195536 |
| FAM219A | family with sequence similarity 219, member A | 0.0194556 |
| ZNF395 | zinc finger protein 395 | 0.0193697 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0193335 |
| ARRDC3 | arrestin domain containing 3 | 0.0193211 |
| RPS2 | ribosomal protein S2 | 0.019147 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0190251 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.01896 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0188025 |
| NONO | non-POU domain containing, octamer-binding | 0.0188011 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0187835 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0187306 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0187041 |
| ACTN4 | actinin, alpha 4 | 0.0185713 |
| HDGF | hepatoma-derived growth factor | 0.0185547 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0184232 |
| FBXO42 | F-box protein 42 | 0.0182563 |
| ZNF638 | zinc finger protein 638 | 0.0179777 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0178949 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.219197 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.202908 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.180368 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.112172 |
| CD44 | CD44 molecule (Indian blood group) | -0.0932695 |
| FTL | ferritin, light polypeptide | -0.0920775 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0864259 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0827342 |
| H1-0 | H1.0 linker histone | -0.0701325 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0698042 |
| ANXA2 | annexin A2 | -0.0690076 |
| COL1A1 | collagen, type I, alpha 1 | -0.0651739 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0646819 |
| FN1 | fibronectin 1 | -0.0620567 |
| IER3 | immediate early response 3 | -0.0603722 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.057694 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0557148 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0540321 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0520793 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0444511 |
| POTEF | POTE ankyrin domain family, member F | -0.0437965 |
| TNNC1 | troponin C type 1 (slow) | -0.0433612 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0427251 |
| LDHA | lactate dehydrogenase A | -0.0425369 |
| PTMA | prothymosin, alpha | -0.0423727 |
| STC1 | stanniocalcin 1 | -0.0395221 |
| INHBA | inhibin, beta A | -0.0384744 |
| CLIC4 | chloride intracellular channel 4 | -0.038449 |
| HLA-B | major histocompatibility complex, class I, B | -0.0378918 |
| TMSB10 | thymosin beta 10 | -0.0376986 |
| FBXO11 | F-box protein 11 | -0.0376556 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0372193 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0372104 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0369312 |
| MAP1B | microtubule-associated protein 1B | -0.0365844 |
| QKI | QKI, KH domain containing, RNA binding | -0.0365408 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.036457 |
| HM13 | histocompatibility (minor) 13 | -0.0363845 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0360787 |
| VCL | vinculin | -0.0358504 |
| MORF4L2 | mortality factor 4 like 2 | -0.0357342 |
| USP15 | ubiquitin specific peptidase 15 | -0.0351854 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0340898 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0340256 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0340172 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0338491 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0335902 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0334584 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.033252 |
| FRMD4A | FERM domain containing 4A | -0.0331586 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0330466 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0330313 |
| CDH13 | cadherin 13 | -0.0328579 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0328431 |
| HPCAL1 | hippocalcin-like 1 | -0.0327611 |
| NF1 | neurofibromin 1 | -0.0322421 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.03206 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0320002 |
| MAP4 | microtubule-associated protein 4 | -0.0317452 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0316774 |
| GNAS | GNAS complex locus | -0.0314081 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0313462 |
| CANX | calnexin | -0.0305378 |
| IL1B | interleukin 1, beta | -0.03053 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0299917 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0299254 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.029737 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0296555 |
| ARF1 | ADP-ribosylation factor 1 | -0.029653 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0295894 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0293729 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0289469 |
| RBM39 | RNA binding motif protein 39 | -0.0288983 |
| RLF | rearranged L-myc fusion | -0.0288642 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0288421 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.028572 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0285235 |
| RAD21 | RAD21 homolog (S. pombe) | -0.028188 |
| SP100 | SP100 nuclear antigen | -0.0278976 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0278395 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0275283 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0270598 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0269354 |
| TPM4 | tropomyosin 4 | -0.0269217 |
| HBP1 | HMG-box transcription factor 1 | -0.0265954 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0264506 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0262679 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0261413 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0260153 |
| SEC24A | SEC24 family member A | -0.0257317 |
| RYBP | RING1 and YY1 binding protein | -0.0254616 |
| TCF12 | transcription factor 12 | -0.0252074 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0252045 |
| ARF4 | ADP-ribosylation factor 4 | -0.0250167 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0249578 |
| TMEM87A | transmembrane protein 87A | -0.024931 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0248899 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.024819 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0246656 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0244224 |
