| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0803593 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0772106 |
| GRAMD4 | GRAM domain containing 4 | 0.0728422 |
| NDRG1 | N-myc downstream regulated 1 | 0.0626505 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0613793 |
| HMGB3 | high mobility group box 3 | 0.0576391 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0559861 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0557068 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.0515755 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0503949 |
| FAM13A | family with sequence similarity 13, member A | 0.0500857 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0479175 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0471072 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0455796 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0420489 |
| VEGFA | vascular endothelial growth factor A | 0.04164 |
| ZNF292 | zinc finger protein 292 | 0.0396107 |
| TPM3 | tropomyosin 3 | 0.0379534 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0374283 |
| NUP58 | nucleoporin 58 | 0.0372671 |
| RPL3 | ribosomal protein L3 | 0.0357097 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0354985 |
| CENPF | centromere protein F, 350/400kDa | 0.0343959 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.034073 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0339305 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0326451 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0315239 |
| CHGB | chromogranin B | 0.0298852 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0292992 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0291278 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0291228 |
| SET | SET nuclear proto-oncogene | 0.0290177 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0285433 |
| IRS2 | insulin receptor substrate 2 | 0.0284673 |
| ENO1 | enolase 1, (alpha) | 0.0282045 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0281879 |
| CCNY | cyclin Y | 0.0280863 |
| CA8 | carbonic anhydrase VIII | 0.0277605 |
| PKM | pyruvate kinase, muscle | 0.0277021 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0275906 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0266104 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0263965 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0261601 |
| CALR | calreticulin | 0.0260429 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0258283 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0256144 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0254831 |
| GOLIM4 | golgi integral membrane protein 4 | 0.0253935 |
| DENND1A | DENN/MADD domain containing 1A | 0.0252261 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0249979 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0247629 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.024517 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0239857 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0236736 |
| HYOU1 | hypoxia up-regulated 1 | 0.023036 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.0221419 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0220749 |
| XPO1 | exportin 1 | 0.0216247 |
| RPL4 | ribosomal protein L4 | 0.0214904 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0213586 |
| HDGF | hepatoma-derived growth factor | 0.0212951 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0211638 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0210727 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0208015 |
| NCKAP1 | NCK-associated protein 1 | 0.0206145 |
| RPS12 | ribosomal protein S12 | 0.0203116 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0202039 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0199555 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0199412 |
| SPAG5 | sperm associated antigen 5 | 0.0195972 |
| TSR1 | TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.0194161 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.019368 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0192973 |
| TPD52 | tumor protein D52 | 0.019282 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0192688 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0192583 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.01912 |
| PEG10 | paternally expressed 10 | 0.0190841 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0189638 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0188461 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0188302 |
| NTS | neurotensin | 0.0187823 |
| RNF145 | ring finger protein 145 | 0.0187284 |
| RREB1 | ras responsive element binding protein 1 | 0.0186884 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0186255 |
| PGK1 | phosphoglycerate kinase 1 | 0.0184754 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0184709 |
| MSN | moesin | 0.018382 |
| TMSB4X | thymosin beta 4, X-linked | 0.0182989 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0182355 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0182137 |
| FMNL2 | formin-like 2 | 0.0180772 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0180529 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0180347 |
| INSIG2 | insulin induced gene 2 | 0.0180206 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0177814 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0173754 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0173637 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0172886 |
| MCL1 | myeloid cell leukemia 1 | 0.0172363 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.144347 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.143636 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.137112 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.119415 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114173 |
| SNTG1 | syntrophin, gamma 1 | -0.103652 |
| CNKSR3 | CNKSR family member 3 | -0.0964739 |
| RIT2 | Ras-like without CAAX 2 | -0.0940311 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0927212 |
| INHBA | inhibin, beta A | -0.0896654 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0859835 |
| NKAIN2 | Na+/K+ transporting ATPase interacting 2 | -0.0844047 |
| SYT1 | synaptotagmin I | -0.0766517 |
| PDE10A | phosphodiesterase 10A | -0.0745154 |
| GPC6 | glypican 6 | -0.0739511 |
| FTL | ferritin, light polypeptide | -0.0685113 |
| GPC5 | glypican 5 | -0.0634738 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0623475 |
| SMYD3 | SET and MYND domain containing 3 | -0.0622858 |
| PTCHD4 | patched domain containing 4 | -0.0605986 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0591695 |
| PTMA | prothymosin, alpha | -0.0566736 |
| TENM1 | teneurin transmembrane protein 1 | -0.0556886 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.05478 |
| MAP1B | microtubule-associated protein 1B | -0.0537398 |
| NBEA | neurobeachin | -0.0534276 |
| EGR1 | early growth response 1 | -0.0530477 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0529357 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0524682 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0518817 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0517059 |
| TXNRD1 | thioredoxin reductase 1 | -0.0483631 |
| FGF14 | fibroblast growth factor 14 | -0.0474035 |
| AOPEP | aminopeptidase O (putative) | -0.0457237 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.045656 |
| DGKB | diacylglycerol kinase, beta 90kDa | -0.0450095 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0444402 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0440566 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0436242 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.042957 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0425759 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.0420034 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0417088 |
| PEX5L | peroxisomal biogenesis factor 5-like | -0.0406648 |
| COL22A1 | collagen, type XXII, alpha 1 | -0.0402674 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -0.0401448 |
| ZNF804A | zinc finger protein 804A | -0.0401053 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0399467 |
| ACTG1 | actin gamma 1 | -0.0393234 |
| RALYL | RALY RNA binding protein-like | -0.0391172 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.0390768 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0389723 |
| PHF14 | PHD finger protein 14 | -0.0387594 |
| H1-0 | H1.0 linker histone | -0.0373105 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0373005 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0369323 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0364945 |
| KCNB2 | potassium channel, voltage gated Shab related subfamily B, member 2 | -0.0363141 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0360529 |
| KCNH7 | potassium channel, voltage gated eag related subfamily H, member 7 | -0.0358023 |
| FOXC1 | forkhead box C1 | -0.0351852 |
| WWOX | WW domain containing oxidoreductase | -0.0351613 |
| CDK13 | cyclin-dependent kinase 13 | -0.0342769 |
| TCF12 | transcription factor 12 | -0.0342441 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -0.0341751 |
| STXBP5L | syntaxin binding protein 5-like | -0.0339388 |
| KCTD8 | potassium channel tetramerization domain containing 8 | -0.0336541 |
| VGF | VGF nerve growth factor inducible | -0.0331646 |
| KCNJ6 | potassium channel, inwardly rectifying subfamily J, member 6 | -0.0330786 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0328522 |
| CPE | carboxypeptidase E | -0.0325222 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0325005 |
| DENND4A | DENN/MADD domain containing 4A | -0.0316825 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | -0.0310499 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0307802 |
| MT2A | metallothionein 2A | -0.030599 |
| UBB | ubiquitin B | -0.0305854 |
| EFNA5 | ephrin-A5 | -0.0305808 |
| CNTNAP5 | contactin associated protein-like 5 | -0.0304493 |
| AUTS2 | autism susceptibility candidate 2 | -0.0304347 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0303889 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0303745 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.029723 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.029704 |
| ST18 | suppression of tumorigenicity 18, zinc finger | -0.0295098 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.029478 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0292364 |
| TOX | thymocyte selection-associated high mobility group box | -0.0290313 |
| KIAA0825 | KIAA0825 | -0.0288186 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0285562 |
| RNF213 | ring finger protein 213 | -0.0285557 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0282381 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0281985 |
| RPS21 | ribosomal protein S21 | -0.0280458 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0279597 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0279185 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0279086 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 | -0.0278769 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0278317 |
| GLCCI1 | glucocorticoid induced 1 | -0.0277105 |
