| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0974022 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0593266 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0584419 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0517536 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0515899 |
| PRELID2 | PRELI domain containing 2 | 0.0500445 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0429365 |
| FMN1 | formin 1 | 0.041003 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0392704 |
| ATP13A3 | ATPase type 13A3 | 0.0332374 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0330541 |
| NAV2 | neuron navigator 2 | 0.0330098 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0323627 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0319126 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0317678 |
| RNF145 | ring finger protein 145 | 0.0313588 |
| KAZN | kazrin, periplakin interacting protein | 0.0308133 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0307558 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0304112 |
| AFDN | afadin, adherens junction formation factor | 0.0299596 |
| CLEC2D | C-type lectin domain family 2, member D | 0.0286484 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0276515 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0271949 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0271194 |
| MSN | moesin | 0.026715 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0261378 |
| NGLY1 | N-glycanase 1 | 0.0257355 |
| FMNL2 | formin-like 2 | 0.0247441 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0240324 |
| CANX | calnexin | 0.0236542 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0222018 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0218206 |
| YEATS2 | YEATS domain containing 2 | 0.0215273 |
| USP3 | ubiquitin specific peptidase 3 | 0.0214842 |
| SPAG9 | sperm associated antigen 9 | 0.0213529 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.021296 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0211617 |
| RPL3 | ribosomal protein L3 | 0.0209692 |
| GPR137B | G protein-coupled receptor 137B | 0.0208477 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0206276 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0206264 |
| ZNF292 | zinc finger protein 292 | 0.0203537 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0197961 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0196375 |
| CEP70 | centrosomal protein 70kDa | 0.0195072 |
| RASA2 | RAS p21 protein activator 2 | 0.0193788 |
| NCKAP1 | NCK-associated protein 1 | 0.0193596 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0193515 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0193479 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0193002 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0192566 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.019115 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0187101 |
| CLTC | clathrin, heavy chain (Hc) | 0.0185753 |
| KLC1 | kinesin light chain 1 | 0.0184449 |
| MAP4 | microtubule-associated protein 4 | 0.0183694 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | 0.0182867 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.017764 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0177549 |
| HMG20B | high mobility group 20B | 0.0176525 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0175713 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0175059 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0173346 |
| CDK19 | cyclin-dependent kinase 19 | 0.0172558 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0171304 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0171059 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0171025 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0169977 |
| ANK2 | ankyrin 2, neuronal | 0.0168609 |
| TXNRD1 | thioredoxin reductase 1 | 0.0167451 |
| HPCAL1 | hippocalcin-like 1 | 0.0165835 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0161976 |
| MYO1B | myosin IB | 0.0161528 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0159266 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0158197 |
| SUCO | SUN domain containing ossification factor | 0.0157208 |
| CCNL1 | cyclin L1 | 0.0156436 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.01562 |
| MLEC | malectin | 0.0156041 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0154859 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0154272 |
| WDR36 | WD repeat domain 36 | 0.0153125 |
| CDC73 | cell division cycle 73 | 0.0152899 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0152709 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0150598 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.014982 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0149687 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0147783 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | 0.0146091 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0144963 |
| COPA | coatomer protein complex, subunit alpha | 0.0144592 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0144555 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0144414 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0144355 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0144297 |
| FAM13A | family with sequence similarity 13, member A | 0.0143004 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0142398 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0142385 |
| WWOX | WW domain containing oxidoreductase | 0.0141869 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0141372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.4106 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.217203 |
| UBC | ubiquitin C | -0.121638 |
| NLGN1 | neuroligin 1 | -0.108008 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.091409 |
| TMSB10 | thymosin beta 10 | -0.0787231 |
| ENO1 | enolase 1, (alpha) | -0.0740286 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0696262 |
| LSAMP | limbic system-associated membrane protein | -0.0689427 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0643887 |
| CCND1 | cyclin D1 | -0.0570061 |
| FTL | ferritin, light polypeptide | -0.0549939 |
| RPS27A | ribosomal protein S27a | -0.0534999 |
| POTEF | POTE ankyrin domain family, member F | -0.0532683 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0525779 |
| RPS6 | ribosomal protein S6 | -0.0513678 |
| RPL23 | ribosomal protein L23 | -0.051233 |
| SQSTM1 | sequestosome 1 | -0.0511536 |
| NRG3 | neuregulin 3 | -0.0510292 |
| LDHA | lactate dehydrogenase A | -0.0499464 |
| PTMA | prothymosin, alpha | -0.0486625 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0482642 |
| ICAM1 | intercellular adhesion molecule 1 | -0.048258 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0420472 |
| RPLP1 | ribosomal protein, large, P1 | -0.0410269 |
| MT2A | metallothionein 2A | -0.0409202 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0404934 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0398855 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0375986 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0368221 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0364004 |
| B2M | beta-2-microglobulin | -0.0361548 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0361529 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0359871 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0359724 |
| RPS3 | ribosomal protein S3 | -0.0357213 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.035141 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0339251 |
| HLA-B | major histocompatibility complex, class I, B | -0.0332039 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0329236 |
| NDRG1 | N-myc downstream regulated 1 | -0.031747 |
| PKM | pyruvate kinase, muscle | -0.0314057 |
| ACTG1 | actin gamma 1 | -0.0311024 |
| SP100 | SP100 nuclear antigen | -0.0307442 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0306401 |
| RPS8 | ribosomal protein S8 | -0.0305778 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0304197 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.030107 |
| PCBP2 | poly(rC) binding protein 2 | -0.0300838 |
| HMGA1 | high mobility group AT-hook 1 | -0.0298077 |
| EMP1 | epithelial membrane protein 1 | -0.0297213 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0291412 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0289905 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0289539 |
| FLNA | filamin A, alpha | -0.0289478 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.028595 |
| HLA-E | major histocompatibility complex, class I, E | -0.028536 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0284185 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0280298 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.0280071 |
| RPL36A | ribosomal protein L36a | -0.0277388 |
| ANXA2 | annexin A2 | -0.0275102 |
| S100A9 | S100 calcium binding protein A9 | -0.0272481 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0271318 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.026878 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0264413 |
| APOD | apolipoprotein D | -0.0263751 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0263595 |
| HLA-A | major histocompatibility complex, class I, A | -0.0261652 |
| IFI44L | interferon-induced protein 44-like | -0.0258375 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0256336 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0254506 |
| RPL15 | ribosomal protein L15 | -0.0252755 |
| HDAC9 | histone deacetylase 9 | -0.025243 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0250876 |
| RPL34 | ribosomal protein L34 | -0.0249712 |
| CD44 | CD44 molecule (Indian blood group) | -0.0249031 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0248551 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.024786 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0245752 |
| NRP2 | neuropilin 2 | -0.0242232 |
| RPL31 | ribosomal protein L31 | -0.0240855 |
| RPL28 | ribosomal protein L28 | -0.0237732 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0236976 |
| RPS13 | ribosomal protein S13 | -0.0236579 |
| RPS24 | ribosomal protein S24 | -0.0235205 |
| AHNAK | AHNAK nucleoprotein | -0.0234268 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0230327 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.022983 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0228626 |
| PRAME | preferentially expressed antigen in melanoma | -0.0227322 |
| CDK12 | cyclin-dependent kinase 12 | -0.0221487 |
| RPLP2 | ribosomal protein, large, P2 | -0.0221333 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0221187 |
| RPL12 | ribosomal protein L12 | -0.0220351 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0215957 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0213497 |
| SVIL | supervillin | -0.020946 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0208232 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0207672 |
