| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.141326 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.112675 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0968834 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0954426 |
| GOLGA4 | golgin A4 | 0.0933085 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0896994 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0836385 |
| ZNF292 | zinc finger protein 292 | 0.0796559 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0676348 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0673648 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.067041 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0659633 |
| RBM39 | RNA binding motif protein 39 | 0.0652936 |
| RTN4 | reticulon 4 | 0.0633014 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0627919 |
| EZR | ezrin | 0.0555037 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0549158 |
| TXNRD1 | thioredoxin reductase 1 | 0.0533325 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0533119 |
| FLNB | filamin B, beta | 0.0531995 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0523709 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0497042 |
| RNF145 | ring finger protein 145 | 0.0492275 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0490464 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0462672 |
| NUP58 | nucleoporin 58 | 0.0460754 |
| QKI | QKI, KH domain containing, RNA binding | 0.0456615 |
| PRELID2 | PRELI domain containing 2 | 0.0453642 |
| ANK2 | ankyrin 2, neuronal | 0.0448006 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.044356 |
| NBAS | neuroblastoma amplified sequence | 0.0439796 |
| PGK1 | phosphoglycerate kinase 1 | 0.0438217 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.043456 |
| NCKAP1 | NCK-associated protein 1 | 0.0411742 |
| RPL3 | ribosomal protein L3 | 0.0407164 |
| JMJD1C | jumonji domain containing 1C | 0.0404668 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.040461 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0402586 |
| B2M | beta-2-microglobulin | 0.039772 |
| CDC73 | cell division cycle 73 | 0.0394661 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0393212 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0387888 |
| PYGB | phosphorylase, glycogen; brain | 0.0384251 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0380071 |
| TMEM41B | transmembrane protein 41B | 0.037845 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0372921 |
| CCNL1 | cyclin L1 | 0.037135 |
| S100A6 | S100 calcium binding protein A6 | 0.0368883 |
| TFG | TRK-fused gene | 0.0368775 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0364617 |
| COG5 | component of oligomeric golgi complex 5 | 0.0364417 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0364116 |
| PTMA | prothymosin, alpha | 0.0361131 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0360431 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.035469 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0353922 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0353148 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0343285 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0341378 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0341132 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0338227 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.033282 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0332725 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0328602 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0327309 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0321131 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0311037 |
| EXT1 | exostosin glycosyltransferase 1 | 0.03052 |
| TMEM65 | transmembrane protein 65 | 0.0298948 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0298855 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0298741 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0297155 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0295803 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0293575 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0293086 |
| TJP1 | tight junction protein 1 | 0.0291999 |
| MATR3 | matrin 3 | 0.0291064 |
| XPO1 | exportin 1 | 0.0290497 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0287611 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0286835 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0286329 |
| SETD5 | SET domain containing 5 | 0.0286039 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.02827 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0282351 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0280842 |
| METTL15 | methyltransferase like 15 | 0.0277724 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0276983 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0276955 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0275905 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0273857 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0273157 |
| SQSTM1 | sequestosome 1 | 0.0272409 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0271378 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0271135 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0269318 |
| NF1 | neurofibromin 1 | 0.0268225 |
| MED13L | mediator complex subunit 13-like | 0.0268041 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0267412 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0261948 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0261275 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.110873 |
| BMP10 | bone morphogenetic protein 10 | -0.109083 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.109035 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0849219 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0847259 |
| FOXP1 | forkhead box P1 | -0.0498341 |
| GLI3 | GLI family zinc finger 3 | -0.0485645 |
| CCND1 | cyclin D1 | -0.0484836 |
| MKI67 | marker of proliferation Ki-67 | -0.0482925 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0453583 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0452894 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0399891 |
| DIAPH3 | diaphanous-related formin 3 | -0.036519 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0331853 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0325129 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0315022 |
| MYO5C | myosin VC | -0.0295209 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0294498 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0293528 |
| NAV2 | neuron navigator 2 | -0.0290833 |
| PDE7B | phosphodiesterase 7B | -0.0283856 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0280722 |
| ZNF438 | zinc finger protein 438 | -0.0271987 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0260393 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0259177 |
| CUX1 | cut-like homeobox 1 | -0.0256579 |
| FER1L6 | fer-1-like family member 6 | -0.0256032 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0255328 |
| TUBA1B | tubulin, alpha 1b | -0.0247665 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0245761 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0243597 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0238822 |
| POTEF | POTE ankyrin domain family, member F | -0.0236693 |
| GSE1 | Gse1 coiled-coil protein | -0.0235885 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0233765 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0215629 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0209026 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0206247 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.020578 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0201969 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.019066 |
| TSC22D1 | TSC22 domain family, member 1 | -0.018998 |
| HJURP | Holliday junction recognition protein | -0.0188812 |
| ITGA10 | integrin, alpha 10 | -0.0185634 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0181683 |
| EMP3 | epithelial membrane protein 3 | -0.01789 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0178081 |
| PKP4 | plakophilin 4 | -0.0176547 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.0166603 |
| APLF | aprataxin and PNKP like factor | -0.0164977 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0164082 |
| SEPTIN9 | septin 9 | -0.0163768 |
| BMP2K | BMP2 inducible kinase | -0.0162376 |
| TOB1 | transducer of ERBB2, 1 | -0.0160295 |
| RPS6 | ribosomal protein S6 | -0.0160125 |
| RPS8 | ribosomal protein S8 | -0.0158625 |
| MACROD2 | MACRO domain containing 2 | -0.0152839 |
| MLIP | muscular LMNA-interacting protein | -0.015178 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0151435 |
| TUBB | tubulin, beta class I | -0.0151395 |
| RPLP1 | ribosomal protein, large, P1 | -0.0150288 |
| HELLS | helicase, lymphoid-specific | -0.0149881 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0148538 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0147788 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0147767 |
| RPL31 | ribosomal protein L31 | -0.0146729 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0146691 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0146088 |
| HMGB1 | high mobility group box 1 | -0.0145686 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0144198 |
| AEBP2 | AE binding protein 2 | -0.0143479 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0142616 |
| RRM2 | ribonucleotide reductase M2 | -0.014079 |
| BCOR | BCL6 corepressor | -0.0137952 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0137448 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0136624 |
| ASTN2 | astrotactin 2 | -0.0136208 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0135994 |
| CENPF | centromere protein F, 350/400kDa | -0.0135016 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0133397 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0133174 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0132869 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0131636 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0131296 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0128029 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0127256 |
| TUBA1C | tubulin, alpha 1c | -0.0126616 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0126059 |
| EBNA1BP2 | EBNA1 binding protein 2 | -0.0124675 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0122785 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 | -0.0122727 |
| INTS6 | integrator complex subunit 6 | -0.0122418 |
| CEP112 | centrosomal protein 112kDa | -0.0121991 |
| UBB | ubiquitin B | -0.0121967 |
| RBL1 | retinoblastoma-like 1 | -0.0121359 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0121295 |
| TBCA | tubulin folding cofactor A | -0.0119457 |
| RPL35A | ribosomal protein L35a | -0.0118973 |
| E2F3 | E2F transcription factor 3 | -0.01188 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0118381 |
