| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.274147 |
| FN1 | fibronectin 1 | 0.0911599 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0825762 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0746649 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0738607 |
| MSN | moesin | 0.0660552 |
| NAV2 | neuron navigator 2 | 0.064666 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0618045 |
| VEGFA | vascular endothelial growth factor A | 0.060462 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0566809 |
| PDE10A | phosphodiesterase 10A | 0.0520017 |
| SMAD3 | SMAD family member 3 | 0.0481316 |
| MYOF | myoferlin | 0.047565 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0465307 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.046067 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0456619 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0448878 |
| CEP250 | centrosomal protein 250kDa | 0.0448148 |
| PRELID2 | PRELI domain containing 2 | 0.0437623 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0430318 |
| FLNB | filamin B, beta | 0.0413812 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0412914 |
| ARRDC3 | arrestin domain containing 3 | 0.040787 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0405038 |
| FLNA | filamin A, alpha | 0.0402418 |
| ATXN1 | ataxin 1 | 0.040195 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0397329 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0391623 |
| VCAN | versican | 0.0359509 |
| HDAC9 | histone deacetylase 9 | 0.0358875 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0342064 |
| RPL3 | ribosomal protein L3 | 0.0341893 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0331831 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0321379 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0315978 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0313859 |
| OPTN | optineurin | 0.0305509 |
| DST | dystonin | 0.0304171 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0296861 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0293394 |
| CDK19 | cyclin-dependent kinase 19 | 0.0282749 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0282383 |
| FLOT1 | flotillin 1 | 0.0278345 |
| SEPTIN9 | septin 9 | 0.0266317 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0263819 |
| PCBP3 | poly(rC) binding protein 3 | 0.0256876 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.025011 |
| DUSP5 | dual specificity phosphatase 5 | 0.0248999 |
| FNIP1 | folliculin interacting protein 1 | 0.024866 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0243665 |
| FAM219A | family with sequence similarity 219, member A | 0.0237533 |
| NGLY1 | N-glycanase 1 | 0.0237476 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0235848 |
| PFKP | phosphofructokinase, platelet | 0.0233422 |
| PCBP2 | poly(rC) binding protein 2 | 0.0233103 |
| CENPF | centromere protein F, 350/400kDa | 0.0229343 |
| YEATS2 | YEATS domain containing 2 | 0.0226876 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.022536 |
| VCL | vinculin | 0.0224822 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0224735 |
| AFDN | afadin, adherens junction formation factor | 0.0224266 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0223908 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.02212 |
| C3 | complement component 3 | 0.0220447 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0210591 |
| KYNU | kynureninase | 0.0210406 |
| TPM3 | tropomyosin 3 | 0.0210375 |
| VMP1 | vacuole membrane protein 1 | 0.0210106 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0208613 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0207552 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.020666 |
| DIAPH3 | diaphanous-related formin 3 | 0.0206372 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0205918 |
| RNF213 | ring finger protein 213 | 0.0205581 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0203919 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0203116 |
| MLPH | melanophilin | 0.0200562 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.019708 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0195766 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0195101 |
| MKI67 | marker of proliferation Ki-67 | 0.0192775 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0192675 |
| CUL4B | cullin 4B | 0.0191797 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.019099 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0189608 |
| TNS3 | tensin 3 | 0.0186517 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0181264 |
| NONO | non-POU domain containing, octamer-binding | 0.0181055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0180582 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0180407 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0177788 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0175515 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0173939 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0173906 |
| MX1 | MX dynamin-like GTPase 1 | 0.0172869 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0170733 |
| CPNE1 | copine I | 0.0170176 |
| SBF2 | SET binding factor 2 | 0.0168112 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0167653 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0166749 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.34025 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.232493 |
| IER3 | immediate early response 3 | -0.162341 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.148121 |
| FTL | ferritin, light polypeptide | -0.13673 |
| HLA-B | major histocompatibility complex, class I, B | -0.126432 |
| TMSB10 | thymosin beta 10 | -0.102288 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0916392 |
| RPS24 | ribosomal protein S24 | -0.0812365 |
| RPS6 | ribosomal protein S6 | -0.0809241 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0750492 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0709797 |
| PTMA | prothymosin, alpha | -0.0700365 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0699429 |
| GLIS3 | GLIS family zinc finger 3 | -0.0665441 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0622825 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0602514 |
| PGK1 | phosphoglycerate kinase 1 | -0.0558272 |
| ANXA2 | annexin A2 | -0.0556437 |
| GNAS | GNAS complex locus | -0.0556144 |
| CD44 | CD44 molecule (Indian blood group) | -0.0553964 |
| RPL35A | ribosomal protein L35a | -0.0542588 |
| RPLP1 | ribosomal protein, large, P1 | -0.0541297 |
| HLA-A | major histocompatibility complex, class I, A | -0.0520075 |
| RPLP0 | ribosomal protein, large, P0 | -0.0509035 |
| RPS8 | ribosomal protein S8 | -0.0482743 |
| MT2A | metallothionein 2A | -0.0482004 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0477083 |
| HLA-E | major histocompatibility complex, class I, E | -0.0476358 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0471538 |
| RPLP2 | ribosomal protein, large, P2 | -0.0467772 |
| CDH13 | cadherin 13 | -0.0466011 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0450736 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0443639 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0436141 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0419261 |
| EGR1 | early growth response 1 | -0.0417207 |
| CANX | calnexin | -0.0416269 |
| HMGA1 | high mobility group AT-hook 1 | -0.0412956 |
| RPL12 | ribosomal protein L12 | -0.0409258 |
| RPL36A | ribosomal protein L36a | -0.0405058 |
| RPS23 | ribosomal protein S23 | -0.0404511 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0370506 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0365679 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0359091 |
| FRMD4A | FERM domain containing 4A | -0.0352923 |
| ACTG1 | actin gamma 1 | -0.035271 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.035188 |
| RPS13 | ribosomal protein S13 | -0.0350743 |
| RAI14 | retinoic acid induced 14 | -0.0349657 |
| RPL23 | ribosomal protein L23 | -0.0346826 |
| ENO1 | enolase 1, (alpha) | -0.0337833 |
| RPL37A | ribosomal protein L37a | -0.0335077 |
| CTSD | cathepsin D | -0.0333298 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0330736 |
| HMGA2 | high mobility group AT-hook 2 | -0.0329244 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0327215 |
| RPL9 | ribosomal protein L9 | -0.0325196 |
| FAM162A | family with sequence similarity 162, member A | -0.0321668 |
| RPL27A | ribosomal protein L27a | -0.0317274 |
| LDHA | lactate dehydrogenase A | -0.0316664 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0313152 |
| RPL32 | ribosomal protein L32 | -0.0312231 |
| B2M | beta-2-microglobulin | -0.0310485 |
| TKT | transketolase | -0.0306806 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.030534 |
| RPL26 | ribosomal protein L26 | -0.0302743 |
| RPS19 | ribosomal protein S19 | -0.0301834 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0300446 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0299635 |
| QKI | QKI, KH domain containing, RNA binding | -0.0298303 |
| CADM1 | cell adhesion molecule 1 | -0.0296091 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.029583 |
| LOX | lysyl oxidase | -0.0292858 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.028866 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0286647 |
| RPL38 | ribosomal protein L38 | -0.0286116 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.028434 |
| RPL36 | ribosomal protein L36 | -0.0283669 |
| RPL19 | ribosomal protein L19 | -0.0283235 |
| DEK | DEK proto-oncogene | -0.0282542 |
| RPS14 | ribosomal protein S14 | -0.028207 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0280727 |
| RPS21 | ribosomal protein S21 | -0.0280395 |
| CAVIN1 | caveolae associated protein 1 | -0.0275277 |
| RPL31 | ribosomal protein L31 | -0.027518 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0268708 |
| MORF4L2 | mortality factor 4 like 2 | -0.0267619 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.026708 |
| JUN | jun proto-oncogene | -0.0265919 |
| RPS27A | ribosomal protein S27a | -0.0265265 |
| AHNAK | AHNAK nucleoprotein | -0.0261397 |
| COL1A1 | collagen, type I, alpha 1 | -0.0260506 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0257725 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.025384 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0252528 |
| RPL34 | ribosomal protein L34 | -0.0251554 |
| RPL28 | ribosomal protein L28 | -0.0249807 |
| TMSB4X | thymosin beta 4, X-linked | -0.0248681 |
| KPNB1 | karyopherin (importin) beta 1 | -0.024762 |
