| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.152219 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.121783 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0971883 |
| B2M | beta-2-microglobulin | 0.0709437 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0670568 |
| MT2A | metallothionein 2A | 0.0580269 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0484182 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0434918 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0426058 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0399801 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.038432 |
| COPA | coatomer protein complex, subunit alpha | 0.0384174 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.038163 |
| GDNF | glial cell derived neurotrophic factor | 0.0379375 |
| FMNL2 | formin-like 2 | 0.0376714 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0372666 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0370414 |
| ADM | adrenomedullin | 0.034972 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0342942 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0322286 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0315595 |
| GOLGB1 | golgin B1 | 0.0302311 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.030148 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0289242 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0289183 |
| PRKD3 | protein kinase D3 | 0.0288817 |
| ANXA1 | annexin A1 | 0.0287283 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.0286399 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0283112 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0275048 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0272421 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0265618 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0265268 |
| JMJD1C | jumonji domain containing 1C | 0.026502 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0264786 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0262292 |
| PTK2 | protein tyrosine kinase 2 | 0.0258885 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0255694 |
| SAR1A | secretion associated, Ras related GTPase 1A | 0.0253728 |
| OTUD4 | OTU deubiquitinase 4 | 0.0250786 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0247859 |
| PCBP2 | poly(rC) binding protein 2 | 0.0247567 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0247398 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0246208 |
| ZNF451 | zinc finger protein 451 | 0.0244905 |
| TPI1 | triosephosphate isomerase 1 | 0.0243855 |
| PKM | pyruvate kinase, muscle | 0.0242812 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0241377 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0241128 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0239089 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.023895 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0237653 |
| AFAP1 | actin filament associated protein 1 | 0.0237256 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0236509 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0236306 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0236268 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0234657 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0233675 |
| YME1L1 | YME1-like 1 ATPase | 0.0231173 |
| ATP11A | ATPase, class VI, type 11A | 0.0230045 |
| ZNF217 | zinc finger protein 217 | 0.0229178 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0228478 |
| PML | promyelocytic leukemia | 0.0228305 |
| RNF114 | ring finger protein 114 | 0.022761 |
| MSN | moesin | 0.0227389 |
| PKN1 | protein kinase N1 | 0.0226682 |
| SPAG9 | sperm associated antigen 9 | 0.0226406 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0224988 |
| SMTN | smoothelin | 0.0224642 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0223505 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0222045 |
| ZNF148 | zinc finger protein 148 | 0.0221744 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.02217 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0220829 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0220688 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0220412 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0219683 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0219434 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0219227 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0218732 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0218106 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0217834 |
| RPL37 | ribosomal protein L37 | 0.0217146 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0216583 |
| PATL1 | protein associated with topoisomerase II homolog 1 (yeast) | 0.0216503 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.0215357 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0215052 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0214329 |
| USP37 | ubiquitin specific peptidase 37 | 0.0212426 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0209833 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0209339 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0207119 |
| ARRDC3 | arrestin domain containing 3 | 0.0206385 |
| FNBP4 | formin binding protein 4 | 0.0204661 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0204222 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0203164 |
| CCNL1 | cyclin L1 | 0.020202 |
| RARS2 | arginyl-tRNA synthetase 2, mitochondrial | 0.0200498 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0199832 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0198174 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.286029 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.272967 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.184795 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.124149 |
| HLA-B | major histocompatibility complex, class I, B | -0.105599 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0938509 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0826102 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0803961 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0803695 |
| CALD1 | caldesmon 1 | -0.0799101 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0786633 |
| VIM | vimentin | -0.0783382 |
| FTL | ferritin, light polypeptide | -0.0782811 |
| VCL | vinculin | -0.0752722 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0675435 |
| CALU | calumenin | -0.0583812 |
| TPM4 | tropomyosin 4 | -0.0573339 |
| TMSB10 | thymosin beta 10 | -0.0561184 |
| HLA-C | major histocompatibility complex, class I, C | -0.0559524 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0543005 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0531088 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.052071 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0501646 |
| ANXA2 | annexin A2 | -0.0493749 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0486215 |
| EGFR | epidermal growth factor receptor | -0.0478485 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.046959 |
| FN1 | fibronectin 1 | -0.0467706 |
| GLIS3 | GLIS family zinc finger 3 | -0.0466871 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0462607 |
| COL6A1 | collagen, type VI, alpha 1 | -0.045603 |
| TMEM165 | transmembrane protein 165 | -0.043804 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.043718 |
| RRBP1 | ribosome binding protein 1 | -0.0425858 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0414883 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0411785 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0409742 |
| DST | dystonin | -0.0406722 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0405782 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0405632 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0404831 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0404545 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.039787 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0394021 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0393303 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.039189 |
| NAV1 | neuron navigator 1 | -0.038969 |
| FAM20C | family with sequence similarity 20, member C | -0.0388585 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0382708 |
| MAP1B | microtubule-associated protein 1B | -0.0374323 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0370034 |
| BSG | basigin (Ok blood group) | -0.0368391 |
| MEF2A | myocyte enhancer factor 2A | -0.0365735 |
| RPL11 | ribosomal protein L11 | -0.036041 |
| POTEF | POTE ankyrin domain family, member F | -0.0360243 |
| CANX | calnexin | -0.0360033 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0351452 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0349439 |
| SQSTM1 | sequestosome 1 | -0.0342996 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0340978 |
| H3-3B | H3.3 histone B | -0.0340801 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0340631 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.033483 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0333318 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0331055 |
| GNAS | GNAS complex locus | -0.0329947 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0328285 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.03263 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0325935 |
| SEPTIN2 | septin 2 | -0.0325666 |
| STC1 | stanniocalcin 1 | -0.032005 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0319036 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0312879 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0306185 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0305756 |
| RPL27A | ribosomal protein L27a | -0.0305474 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.030533 |
| RPS24 | ribosomal protein S24 | -0.0304537 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0302977 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0299665 |
| MAP4 | microtubule-associated protein 4 | -0.029915 |
| ATP13A3 | ATPase type 13A3 | -0.0296938 |
| PALLD | palladin, cytoskeletal associated protein | -0.0295022 |
| COL5A1 | collagen, type V, alpha 1 | -0.0294183 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.0292316 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0292035 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0290246 |
| RASAL2 | RAS protein activator like 2 | -0.0290194 |
| EFNA5 | ephrin-A5 | -0.0290129 |
| LCOR | ligand dependent nuclear receptor corepressor | -0.0288201 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0287973 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0287304 |
| RNF216 | ring finger protein 216 | -0.0284805 |
| RAI14 | retinoic acid induced 14 | -0.0282326 |
| CALR | calreticulin | -0.0279567 |
| RORA | RAR-related orphan receptor A | -0.0278759 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.027808 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0277094 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0276718 |
| CDK13 | cyclin-dependent kinase 13 | -0.0274564 |
