| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.12466 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0673856 |
| PTMA | prothymosin, alpha | 0.0590555 |
| FAM13A | family with sequence similarity 13, member A | 0.0536148 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0531422 |
| CD109 | CD109 molecule | 0.0522612 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0475074 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0460791 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0386673 |
| HDGF | hepatoma-derived growth factor | 0.0382645 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.03726 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0364286 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0363962 |
| PRELID2 | PRELI domain containing 2 | 0.0361586 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0358025 |
| TMSB4X | thymosin beta 4, X-linked | 0.0355575 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0345421 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0339503 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0311066 |
| TPM3 | tropomyosin 3 | 0.0292381 |
| HMGB3 | high mobility group box 3 | 0.0289455 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0288465 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0276631 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0273202 |
| OGA | O-GlcNAcase | 0.0268775 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0267867 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0267437 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0266305 |
| HELZ | helicase with zinc finger | 0.0265992 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0264001 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0263443 |
| XPO1 | exportin 1 | 0.0259716 |
| RAB18 | RAB18, member RAS oncogene family | 0.0255869 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0251869 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0247815 |
| PLIN2 | perilipin 2 | 0.0247633 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0243754 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0241675 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0240169 |
| TPI1 | triosephosphate isomerase 1 | 0.0238928 |
| RPL3 | ribosomal protein L3 | 0.0237983 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0234315 |
| INSIG2 | insulin induced gene 2 | 0.0232809 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0232701 |
| TFG | TRK-fused gene | 0.023213 |
| PLEC | plectin | 0.0228386 |
| B2M | beta-2-microglobulin | 0.0227372 |
| STC2 | stanniocalcin 2 | 0.0226179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0223994 |
| AFDN | afadin, adherens junction formation factor | 0.0221975 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0221296 |
| RNF145 | ring finger protein 145 | 0.021719 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0216668 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0213747 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0207768 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0207415 |
| COPA | coatomer protein complex, subunit alpha | 0.0207201 |
| YME1L1 | YME1-like 1 ATPase | 0.0206595 |
| ARRDC3 | arrestin domain containing 3 | 0.0205797 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0205347 |
| FLNB | filamin B, beta | 0.0203642 |
| FLNA | filamin A, alpha | 0.0202922 |
| FAM193B | family with sequence similarity 193, member B | 0.0202776 |
| CALR | calreticulin | 0.0202168 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0200742 |
| AHR | aryl hydrocarbon receptor | 0.0199136 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.019912 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0196329 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0196106 |
| SMOX | spermine oxidase | 0.0193709 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0192619 |
| CEP250 | centrosomal protein 250kDa | 0.0191178 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0191003 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0188985 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0188377 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0187198 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0186662 |
| MYOF | myoferlin | 0.0185881 |
| RPS2 | ribosomal protein S2 | 0.018548 |
| MKRN1 | makorin ring finger protein 1 | 0.0185243 |
| AHNAK | AHNAK nucleoprotein | 0.0182328 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.018173 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0179608 |
| GOLGA4 | golgin A4 | 0.0177771 |
| H1-4 | H1.4 linker histone, cluster member | 0.0175459 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0175286 |
| SFTPA2 | surfactant protein A2 | 0.0175248 |
| NUP58 | nucleoporin 58 | 0.0174609 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0174041 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0173572 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0173235 |
| ATL2 | atlastin GTPase 2 | 0.0171756 |
| FMNL2 | formin-like 2 | 0.0169094 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.01683 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0167999 |
| NBAS | neuroblastoma amplified sequence | 0.0167841 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0165827 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0165652 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0164954 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0161777 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.521388 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.150908 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.149584 |
| MT2A | metallothionein 2A | -0.105602 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.103124 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0987319 |
| FTL | ferritin, light polypeptide | -0.0821042 |
| VCL | vinculin | -0.0716491 |
| OSMR | oncostatin M receptor | -0.0700944 |
| MAP1B | microtubule-associated protein 1B | -0.0594051 |
| NTN4 | netrin 4 | -0.0550389 |
| SYT1 | synaptotagmin I | -0.0549979 |
| TMSB10 | thymosin beta 10 | -0.0546034 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0530755 |
| TMEM156 | transmembrane protein 156 | -0.0527075 |
| VIM | vimentin | -0.0483113 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.047262 |
| FN1 | fibronectin 1 | -0.0472588 |
| NRP1 | neuropilin 1 | -0.0466686 |
| HMGA2 | high mobility group AT-hook 2 | -0.0464019 |
| RPLP1 | ribosomal protein, large, P1 | -0.0452432 |
| NRG1 | neuregulin 1 | -0.0437526 |
| CANX | calnexin | -0.0427247 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0395846 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0395253 |
| GLIS3 | GLIS family zinc finger 3 | -0.0392303 |
| S100A6 | S100 calcium binding protein A6 | -0.0377693 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0372343 |
| HLA-B | major histocompatibility complex, class I, B | -0.0362743 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0357268 |
| PALLD | palladin, cytoskeletal associated protein | -0.0353044 |
| RAB31 | RAB31, member RAS oncogene family | -0.0344175 |
| HMGA1 | high mobility group AT-hook 1 | -0.0333421 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0325513 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0323295 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0315252 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0311535 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0309879 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0308868 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0305311 |
| EFNA5 | ephrin-A5 | -0.0302163 |
| CD44 | CD44 molecule (Indian blood group) | -0.0299988 |
| EGR1 | early growth response 1 | -0.029671 |
| RPS6 | ribosomal protein S6 | -0.0290195 |
| ASPH | aspartate beta-hydroxylase | -0.028563 |
| RPL35A | ribosomal protein L35a | -0.0282899 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0282494 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0281416 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0273667 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0269946 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0267775 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0266394 |
| FHL2 | four and a half LIM domains 2 | -0.0264837 |
| PELO | pelota homolog (Drosophila) | -0.0262266 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0260699 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0257033 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0253253 |
| ETV1 | ets variant 1 | -0.025235 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0251285 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0249417 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0248043 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0243044 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0242138 |
| RTN4 | reticulon 4 | -0.0241605 |
| FOXP1 | forkhead box P1 | -0.024142 |
| TOP1 | topoisomerase (DNA) I | -0.0241379 |
| RASAL2 | RAS protein activator like 2 | -0.0239747 |
| RPS24 | ribosomal protein S24 | -0.0238397 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0232379 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0231114 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0230044 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.022888 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0224636 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0220652 |
| VMP1 | vacuole membrane protein 1 | -0.0219415 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0218677 |
| UBXN4 | UBX domain protein 4 | -0.02181 |
| RIGI | RNA sensor RIG-I | -0.0217128 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0215362 |
| RPS16 | ribosomal protein S16 | -0.0212915 |
| TXNRD1 | thioredoxin reductase 1 | -0.0210381 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0208113 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.020627 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0206031 |
| RPS8 | ribosomal protein S8 | -0.0205818 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.02017 |
| ITGB5 | integrin, beta 5 | -0.0200288 |
| ARF1 | ADP-ribosylation factor 1 | -0.0199716 |
| RAB10 | RAB10, member RAS oncogene family | -0.0198095 |
| RHEB | Ras homolog enriched in brain | -0.019805 |
| SVIL | supervillin | -0.0197933 |
| ATF6 | activating transcription factor 6 | -0.0197857 |
| SMAD3 | SMAD family member 3 | -0.0196924 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0195926 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0195856 |
| RPL12 | ribosomal protein L12 | -0.0193883 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0191112 |
| SMYD3 | SET and MYND domain containing 3 | -0.0190264 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0189379 |
| GLCCI1 | glucocorticoid induced 1 | -0.0188991 |
