| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.14047 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0965983 |
| DSPP | dentin sialophosphoprotein | 0.0849382 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0826092 |
| PLEC | plectin | 0.0673606 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0660388 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0634996 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0585738 |
| SET | SET nuclear proto-oncogene | 0.0578224 |
| RPL3 | ribosomal protein L3 | 0.0550862 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0528972 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0485338 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0476047 |
| NCKAP1 | NCK-associated protein 1 | 0.0475223 |
| PCBP2 | poly(rC) binding protein 2 | 0.0460586 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0454893 |
| TMSB4X | thymosin beta 4, X-linked | 0.0449857 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0432713 |
| MKRN1 | makorin ring finger protein 1 | 0.0425425 |
| KRT18 | keratin 18, type I | 0.0406474 |
| MED13L | mediator complex subunit 13-like | 0.0402229 |
| CCNL1 | cyclin L1 | 0.0383762 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0382131 |
| TMF1 | TATA element modulatory factor 1 | 0.0369914 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0369546 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0364226 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364009 |
| TPM3 | tropomyosin 3 | 0.0363844 |
| XPO1 | exportin 1 | 0.0357468 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0346627 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0337476 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0335951 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0331172 |
| FLNA | filamin A, alpha | 0.0328866 |
| PNN | pinin, desmosome associated protein | 0.0323199 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0317797 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.031433 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0311618 |
| FMR1 | fragile X mental retardation 1 | 0.0311259 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0305712 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0305103 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0304894 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0298764 |
| AFDN | afadin, adherens junction formation factor | 0.0292186 |
| YME1L1 | YME1-like 1 ATPase | 0.0287033 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0286793 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0286752 |
| TFG | TRK-fused gene | 0.028436 |
| ADM | adrenomedullin | 0.0283016 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0280745 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.027859 |
| ATL2 | atlastin GTPase 2 | 0.0277862 |
| CEP250 | centrosomal protein 250kDa | 0.0277547 |
| HDGF | hepatoma-derived growth factor | 0.0273752 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0272525 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.026933 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0267899 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0259732 |
| HOXB6 | homeobox B6 | 0.0259154 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0258334 |
| HYOU1 | hypoxia up-regulated 1 | 0.0253546 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.025335 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0251926 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0249406 |
| RNF145 | ring finger protein 145 | 0.0246016 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0245858 |
| CPNE1 | copine I | 0.0234912 |
| RPS3 | ribosomal protein S3 | 0.0234399 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0232842 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0232185 |
| HSPA8 | heat shock 70kDa protein 8 | 0.023152 |
| SEPTIN9 | septin 9 | 0.0228922 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0228234 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0227768 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0226107 |
| RPS2 | ribosomal protein S2 | 0.0225781 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0223101 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain | 0.0222639 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0222064 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0221223 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0220113 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0219926 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0217356 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0216256 |
| MYO18A | myosin XVIIIA | 0.0215955 |
| MTMR3 | myotubularin related protein 3 | 0.021532 |
| XPOT | exportin, tRNA | 0.0212157 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0210839 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.021038 |
| SART1 | squamous cell carcinoma antigen recognized by T cells | 0.0207431 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0207344 |
| SNX9 | sorting nexin 9 | 0.0207285 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0205973 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0204839 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0202408 |
| OPTN | optineurin | 0.0199129 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0198793 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.019788 |
| RAB18 | RAB18, member RAS oncogene family | 0.019764 |
| DYNLL2 | dynein, light chain, LC8-type 2 | 0.019711 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.193454 |
| FTL | ferritin, light polypeptide | -0.145131 |
| ANXA2 | annexin A2 | -0.111441 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.109286 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0899677 |
| TMSB10 | thymosin beta 10 | -0.0882462 |
| EGR1 | early growth response 1 | -0.0845669 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0783176 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0771672 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0682605 |
| RPLP1 | ribosomal protein, large, P1 | -0.0652021 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0651082 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0634131 |
| RPL35A | ribosomal protein L35a | -0.0603332 |
| H1-0 | H1.0 linker histone | -0.0553221 |
| BCL2L1 | BCL2-like 1 | -0.0525675 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0507806 |
| RHEB | Ras homolog enriched in brain | -0.0506535 |
| IER3 | immediate early response 3 | -0.0487866 |
| RPS21 | ribosomal protein S21 | -0.0481766 |
| LDHA | lactate dehydrogenase A | -0.0475903 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0467011 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0466122 |
| IFRD1 | interferon-related developmental regulator 1 | -0.046501 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.046109 |
| GNAS | GNAS complex locus | -0.04596 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0456105 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0453184 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0446906 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0444469 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0439752 |
| RPS24 | ribosomal protein S24 | -0.0437736 |
| PLSCR1 | phospholipid scramblase 1 | -0.0437541 |
| RPL28 | ribosomal protein L28 | -0.0433407 |
| HM13 | histocompatibility (minor) 13 | -0.0432987 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0431711 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0421756 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0420118 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0418481 |
| VCL | vinculin | -0.0417745 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.041556 |
| LOC112694756 | uncharaterized LOC112694756 | -0.041162 |
| MYO1E | myosin IE | -0.0406137 |
| CCND1 | cyclin D1 | -0.0401725 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0397844 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0394877 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0389268 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0387427 |
| OXSR1 | oxidative stress responsive 1 | -0.0376896 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0370448 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0370226 |
| RPL12 | ribosomal protein L12 | -0.0367843 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0366019 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0361496 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0354289 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0350691 |
| SQSTM1 | sequestosome 1 | -0.0347223 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0345357 |
| NEBL | nebulette | -0.0336625 |
| S100A10 | S100 calcium binding protein A10 | -0.0332919 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0330735 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0328925 |
| SP100 | SP100 nuclear antigen | -0.0325576 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0324049 |
| CST3 | cystatin C | -0.0323173 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0321959 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0319836 |
| RPS6 | ribosomal protein S6 | -0.0319163 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0319154 |
| EHBP1 | EH domain binding protein 1 | -0.031853 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.031732 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0313617 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0313082 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0312935 |
| CALU | calumenin | -0.0312225 |
| HMGA1 | high mobility group AT-hook 1 | -0.0303829 |
| RPL31 | ribosomal protein L31 | -0.0301468 |
| TMEM123 | transmembrane protein 123 | -0.0301168 |
| PKP4 | plakophilin 4 | -0.0300931 |
| CLDN4 | claudin 4 | -0.0296724 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0295787 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0294398 |
| FUS | FUS RNA binding protein | -0.0290111 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0289607 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0288243 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0286688 |
| RPL19 | ribosomal protein L19 | -0.0286325 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.028519 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0284362 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0281917 |
| NF1 | neurofibromin 1 | -0.0281792 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0280948 |
| JMJD1C | jumonji domain containing 1C | -0.0280307 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.0278399 |
| HMGB1 | high mobility group box 1 | -0.0275898 |
| RPLP0 | ribosomal protein, large, P0 | -0.0270606 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0266975 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0265597 |
| MORF4L2 | mortality factor 4 like 2 | -0.0263718 |
| CANX | calnexin | -0.0263308 |
