| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.161037 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101714 |
| PLEC | plectin | 0.0851027 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0840097 |
| DSPP | dentin sialophosphoprotein | 0.077234 |
| RPL3 | ribosomal protein L3 | 0.0765217 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0754146 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0753361 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0750236 |
| ANLN | anillin, actin binding protein | 0.0740305 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0657171 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0634161 |
| ZNF292 | zinc finger protein 292 | 0.0631507 |
| MSN | moesin | 0.0610936 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0597291 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0573851 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.056761 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0565964 |
| PCBP2 | poly(rC) binding protein 2 | 0.0547408 |
| SET | SET nuclear proto-oncogene | 0.054735 |
| KRT18 | keratin 18, type I | 0.0534293 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0513931 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0502871 |
| PKM | pyruvate kinase, muscle | 0.0500926 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0498731 |
| KRT8 | keratin 8, type II | 0.0471672 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0467444 |
| KIZ | kizuna centrosomal protein | 0.0459671 |
| ABHD2 | abhydrolase domain containing 2 | 0.0458444 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0439519 |
| RPS12 | ribosomal protein S12 | 0.0438217 |
| RPS3 | ribosomal protein S3 | 0.0434812 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0425699 |
| DIAPH3 | diaphanous-related formin 3 | 0.0424432 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0417074 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0404159 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0401871 |
| RPS2 | ribosomal protein S2 | 0.0400443 |
| TPM3 | tropomyosin 3 | 0.0392809 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0385588 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0384946 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0381906 |
| PGK1 | phosphoglycerate kinase 1 | 0.0381405 |
| ENO1 | enolase 1, (alpha) | 0.036474 |
| PCM1 | pericentriolar material 1 | 0.035979 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0359664 |
| XPO1 | exportin 1 | 0.0359219 |
| PRELID2 | PRELI domain containing 2 | 0.035361 |
| YEATS2 | YEATS domain containing 2 | 0.0346236 |
| PNN | pinin, desmosome associated protein | 0.0334457 |
| NUP58 | nucleoporin 58 | 0.0334152 |
| INSIG2 | insulin induced gene 2 | 0.0331758 |
| TPI1 | triosephosphate isomerase 1 | 0.0324925 |
| PDE8A | phosphodiesterase 8A | 0.0323009 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0321625 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0316808 |
| TMF1 | TATA element modulatory factor 1 | 0.0316746 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0316462 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0313316 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0311382 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0310832 |
| CENPF | centromere protein F, 350/400kDa | 0.0300691 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0295947 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.029458 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.02931 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.029163 |
| RAB6A | RAB6A, member RAS oncogene family | 0.028899 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0286594 |
| H1-4 | H1.4 linker histone, cluster member | 0.0285164 |
| RPL37A | ribosomal protein L37a | 0.0284974 |
| ITGA6 | integrin, alpha 6 | 0.0284424 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0281535 |
| TXNIP | thioredoxin interacting protein | 0.0279427 |
| CDK19 | cyclin-dependent kinase 19 | 0.0279341 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0277019 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0276042 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0275297 |
| MKRN1 | makorin ring finger protein 1 | 0.0274887 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0274857 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0274239 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0272344 |
| KLC1 | kinesin light chain 1 | 0.0269438 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0266917 |
| H1-2 | H1.2 linker histone, cluster member | 0.0262181 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0262058 |
| GOLGA4 | golgin A4 | 0.0262039 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0258781 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0257021 |
| CBX5 | chromobox homolog 5 | 0.0256588 |
| FNIP1 | folliculin interacting protein 1 | 0.0256055 |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.0250173 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0249138 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0247343 |
| NONO | non-POU domain containing, octamer-binding | 0.0247127 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0245571 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0242012 |
| AFDN | afadin, adherens junction formation factor | 0.0241972 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.023986 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0239447 |
| HDGF | hepatoma-derived growth factor | 0.0237968 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.209363 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115569 |
| VCL | vinculin | -0.104384 |
| SYT1 | synaptotagmin I | -0.0937615 |
| ANXA2 | annexin A2 | -0.0935177 |
| CCND1 | cyclin D1 | -0.0821175 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0819314 |
| SPATA13 | spermatogenesis associated 13 | -0.0776658 |
| EGR1 | early growth response 1 | -0.0729709 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.072805 |
| CDH13 | cadherin 13 | -0.0701863 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0653916 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0627327 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0623684 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0620487 |
| CDK6 | cyclin-dependent kinase 6 | -0.0613812 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0608436 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0588653 |
| INTS6 | integrator complex subunit 6 | -0.054374 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0538987 |
| TNS3 | tensin 3 | -0.0532443 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0525878 |
| RPS24 | ribosomal protein S24 | -0.0509679 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | -0.0478372 |
| LMO7 | LIM domain 7 | -0.0477372 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0472074 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0463389 |
| TMEM123 | transmembrane protein 123 | -0.0458457 |
| ACTG1 | actin gamma 1 | -0.0458166 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0431118 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.039209 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.039186 |
| MTAP | methylthioadenosine phosphorylase | -0.0388074 |
| PHF14 | PHD finger protein 14 | -0.0376089 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0373375 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0369341 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0363833 |
| BCL2L1 | BCL2-like 1 | -0.0360554 |
| COBL | cordon-bleu WH2 repeat protein | -0.03582 |
| FRMD5 | FERM domain containing 5 | -0.0335731 |
| YAP1 | Yes-associated protein 1 | -0.0330946 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0330098 |
| TCF12 | transcription factor 12 | -0.0329898 |
| IER3 | immediate early response 3 | -0.0325071 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0318251 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | -0.0317387 |
| RPLP1 | ribosomal protein, large, P1 | -0.0316888 |
| GPHN | gephyrin | -0.031593 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0312214 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0309264 |
| TMSB10 | thymosin beta 10 | -0.0309161 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.030456 |
| AK1 | adenylate kinase 1 | -0.0303106 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0298936 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0298724 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.029857 |
| RPL35A | ribosomal protein L35a | -0.0297828 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0297312 |
| ACTN4 | actinin, alpha 4 | -0.0297156 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0294876 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0291834 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0288211 |
| UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | -0.0284737 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0284527 |
| HMGB1 | high mobility group box 1 | -0.0277604 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0273261 |
| TASP1 | taspase, threonine aspartase, 1 | -0.0273119 |
| TMEM163 | transmembrane protein 163 | -0.0272584 |
| VMP1 | vacuole membrane protein 1 | -0.0272387 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0269876 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0268475 |
| EHBP1 | EH domain binding protein 1 | -0.0267975 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0267131 |
| CDK12 | cyclin-dependent kinase 12 | -0.0265329 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0264766 |
| UBAP2 | ubiquitin associated protein 2 | -0.0264522 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0264462 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.026359 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0263197 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0262716 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0261996 |
| SERINC5 | serine incorporator 5 | -0.0261992 |
| MYO1E | myosin IE | -0.0260713 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0258753 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0258699 |
| CBFB | core-binding factor, beta subunit | -0.0258463 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0257983 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0257269 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0256417 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0256249 |
| FUS | FUS RNA binding protein | -0.0254126 |
| SMYD3 | SET and MYND domain containing 3 | -0.0248649 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0248606 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0248424 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0245593 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0245356 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0244935 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.024184 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0241527 |
| SYNJ2 | synaptojanin 2 | -0.0241369 |
