| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Edoxaban (tosylate monohydrate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Edoxaban (tosylate monohydrate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.248661 |
| COL6A3 | collagen, type VI, alpha 3 | 0.2093 |
| STC1 | stanniocalcin 1 | 0.1633 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.151478 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.12665 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.125095 |
| FAM13A | family with sequence similarity 13, member A | 0.12293 |
| DST | dystonin | 0.111382 |
| HMGA2 | high mobility group AT-hook 2 | 0.107705 |
| COL6A2 | collagen, type VI, alpha 2 | 0.106157 |
| INHBA | inhibin, beta A | 0.10413 |
| ATP13A3 | ATPase type 13A3 | 0.0956428 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0950778 |
| FMNL2 | formin-like 2 | 0.0944407 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0869718 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0857194 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0814423 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.079245 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0790917 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0721599 |
| SPAG9 | sperm associated antigen 9 | 0.0693912 |
| ASPH | aspartate beta-hydroxylase | 0.0693476 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0687768 |
| ADM | adrenomedullin | 0.0667436 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0665152 |
| ENO1 | enolase 1, (alpha) | 0.0632369 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0629373 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0624978 |
| CALR | calreticulin | 0.062361 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0611024 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0592244 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0585334 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.056447 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0560996 |
| GOLGA4 | golgin A4 | 0.0557589 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0535805 |
| AHNAK | AHNAK nucleoprotein | 0.0528458 |
| MMP12 | matrix metallopeptidase 12 | 0.0522865 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0504749 |
| TMSB4X | thymosin beta 4, X-linked | 0.0495084 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0491358 |
| CANX | calnexin | 0.0481782 |
| FN1 | fibronectin 1 | 0.0478073 |
| PRELID2 | PRELI domain containing 2 | 0.0475907 |
| COPA | coatomer protein complex, subunit alpha | 0.046609 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0462587 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0460164 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0458424 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0456432 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0455207 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0454637 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0452258 |
| VIM | vimentin | 0.0446298 |
| APP | amyloid beta (A4) precursor protein | 0.0443156 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0442501 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.044158 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.043104 |
| NAV2 | neuron navigator 2 | 0.0430274 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0425756 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.042101 |
| HELZ | helicase with zinc finger | 0.0418133 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0416865 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0412221 |
| NUP58 | nucleoporin 58 | 0.0409169 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0407685 |
| LOX | lysyl oxidase | 0.0398972 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0398829 |
| PKM | pyruvate kinase, muscle | 0.0398299 |
| B2M | beta-2-microglobulin | 0.0395165 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0392058 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0382727 |
| PGK1 | phosphoglycerate kinase 1 | 0.0381516 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0380101 |
| OGA | O-GlcNAcase | 0.0379977 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0377645 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.036659 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0365735 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0361042 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.035752 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0352955 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0350091 |
| NGLY1 | N-glycanase 1 | 0.0346865 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0345082 |
| COL4A1 | collagen, type IV, alpha 1 | 0.033485 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0330066 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0329899 |
| PTMA | prothymosin, alpha | 0.0329365 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0329232 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0324721 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0324504 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0318221 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0317599 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0317426 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0313007 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0309302 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.030862 |
| FBN1 | fibrillin 1 | 0.0307732 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0307552 |
| MMP1 | matrix metallopeptidase 1 | 0.0296385 |
| HMGB2 | high mobility group box 2 | 0.0295395 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.217145 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0551998 |
| CD44 | CD44 molecule (Indian blood group) | -0.0498135 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0377114 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0371366 |
| POTEF | POTE ankyrin domain family, member F | -0.0363858 |
| FTL | ferritin, light polypeptide | -0.0361146 |
| COL1A1 | collagen, type I, alpha 1 | -0.0354094 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0353207 |
| NDRG1 | N-myc downstream regulated 1 | -0.0335044 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0331653 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0306294 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0295963 |
| COL1A2 | collagen, type I, alpha 2 | -0.0283238 |
| EGR1 | early growth response 1 | -0.0279266 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0278732 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0265325 |
| IGF2 | insulin-like growth factor 2 | -0.026495 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0264193 |
| HMGA1 | high mobility group AT-hook 1 | -0.0260665 |
| PLPP3 | phospholipid phosphatase 3 | -0.0231235 |
| NOTCH3 | notch 3 | -0.0228424 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0213141 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0208442 |
| ACTG1 | actin gamma 1 | -0.0205643 |
| CLMP | CXADR-like membrane protein | -0.0187928 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0183417 |
| KIAA1549L | KIAA1549-like | -0.018 |
| CCND1 | cyclin D1 | -0.0179037 |
| TAPBP | TAP binding protein (tapasin) | -0.0177825 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0175402 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0174848 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0166946 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0164876 |
| EGFR | epidermal growth factor receptor | -0.0162791 |
| TMEM165 | transmembrane protein 165 | -0.0159177 |
| BSG | basigin (Ok blood group) | -0.0158888 |
| MEF2D | myocyte enhancer factor 2D | -0.0157715 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 | -0.0155111 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0154991 |
| SEPTIN11 | septin 11 | -0.0153373 |
| TSHZ3 | teashirt zinc finger homeobox 3 | -0.0149278 |
| HAS2 | hyaluronan synthase 2 | -0.0144402 |
| FLNA | filamin A, alpha | -0.0141851 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0137634 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0136179 |
| MYADM | myeloid-associated differentiation marker | -0.0135582 |
| PFN1 | profilin 1 | -0.0135248 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0135161 |
| RNASEH2A | ribonuclease H2, subunit A | -0.013338 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0124662 |
| SFRP1 | secreted frizzled-related protein 1 | -0.012243 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.01223 |
| ATN1 | atrophin 1 | -0.0122067 |
| GRN | granulin | -0.012161 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0121564 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0120951 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.012001 |
| SOD3 | superoxide dismutase 3, extracellular | -0.0119599 |
| COL5A3 | collagen, type V, alpha 3 | -0.0118681 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0117629 |
| TAGLN2 | transgelin 2 | -0.0116461 |
| TXNRD1 | thioredoxin reductase 1 | -0.0115624 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0114691 |
| POMP | proteasome maturation protein | -0.0111547 |
| PRRC2A | proline-rich coiled-coil 2A | -0.0111135 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | -0.0109606 |
| MAGED1 | melanoma antigen family D1 | -0.010955 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | -0.0106355 |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | -0.0105968 |
| ZFP36 | ZFP36 ring finger protein | -0.0105731 |
| GDAP2 | ganglioside induced differentiation associated protein 2 | -0.0105475 |
| KMT2D | lysine (K)-specific methyltransferase 2D | -0.0105376 |
| CTSD | cathepsin D | -0.0105074 |
| PLAU | plasminogen activator, urokinase | -0.0104842 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 | -0.0104516 |
| NUP153 | nucleoporin 153kDa | -0.0104374 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0104236 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0103469 |
| RHOA | ras homolog family member A | -0.0102839 |
| SOCS5 | suppressor of cytokine signaling 5 | -0.0102747 |
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | -0.0101451 |
| RPS5 | ribosomal protein S5 | -0.0101235 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0100939 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0100712 |
| EIF3L | eukaryotic translation initiation factor 3, subunit L | -0.0100273 |
| CPA6 | carboxypeptidase A6 | -0.00977498 |
| SURF4 | surfeit 4 | -0.00977462 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.00959094 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.00957441 |
| RPS24 | ribosomal protein S24 | -0.00947151 |
| ARCN1 | archain 1 | -0.00945998 |
| COLGALT1 | collagen beta(1-O)galactosyltransferase 1 | -0.00944832 |
| MAP1B | microtubule-associated protein 1B | -0.00938401 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0092641 |
| AGRN | agrin | -0.00918996 |
| BSDC1 | BSD domain containing 1 | -0.00918537 |
| TUBA1B | tubulin, alpha 1b | -0.00917306 |
| TDG | thymine-DNA glycosylase | -0.00910864 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | -0.00910718 |
