Ehrlichiosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores 2025
Category disease or phenotype associations
Type disease
Description A primary bacterial infectious disease that results_in infection located_in leukocyte, has_material_basis_in Ehrlichia chaffeensis or Anaplasma phagocytophilum, which are transmitted_by lone start stick and transmitted_by black-legged tick respectively. The infection has_symptom headache, has_symptom muscle aches, has_symptom fatigue and has_symptom rash. (Human Disease Ontology, DOID_10242)
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Genes

174 genes co-occuring with the disease Ehrlichiosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores 2025 dataset.

Symbol Name Standardized Value
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.846
TXNL1 thioredoxin-like 1 2.644
ETF1 eukaryotic translation termination factor 1 2.476
DNASE1L1 deoxyribonuclease I-like 1 2.408
ERVFRD-1 endogenous retrovirus group FRD, member 1 2.217
ERV3-1 endogenous retrovirus group 3, member 1 2.217
CENPV centromere protein V 2.211
ERVW-1 endogenous retrovirus group W, member 1 2.172
ANKRD46 ankyrin repeat domain 46 2.169
IFNG interferon, gamma 2.068
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.962
RAB5A RAB5A, member RAS oncogene family 1.957
CD4 CD4 molecule 1.926
EDC4 enhancer of mRNA decapping 4 1.922
PCGF5 polycomb group ring finger 5 1.916
CD8A CD8a molecule 1.851
SELPLG selectin P ligand 1.833
IL10 interleukin 10 1.817
ALB albumin 1.803
TLR2 toll-like receptor 2 1.803
COL4A5 collagen, type IV, alpha 5 1.8
TNF tumor necrosis factor 1.77
MYD88 myeloid differentiation primary response 88 1.721
TBP TATA box binding protein 1.721
IL1B interleukin 1, beta 1.712
EEA1 early endosome antigen 1 1.686
IFNAR1 interferon (alpha, beta and omega) receptor 1 1.676
ANKFY1 ankyrin repeat and FYVE domain containing 1 1.651
CRP C-reactive protein, pentraxin-related 1.64
CS citrate synthase 1.632
IL6 interleukin 6 1.615
IL18 interleukin 18 1.601
STX16 syntaxin 16 1.601
CYBB cytochrome b-245, beta polypeptide 1.591
CXCL8 chemokine (C-X-C motif) ligand 8 1.55
HSPE1 heat shock 10kDa protein 1 1.543
HP haptoglobin 1.54
SGSM3 small G protein signaling modulator 3 1.516
IL1A interleukin 1, alpha 1.507
TMEM185A transmembrane protein 185A 1.505
NOD2 nucleotide-binding oligomerization domain containing 2 1.481
F3 coagulation factor III (thromboplastin, tissue factor) 1.46
NLRC4 NLR family, CARD domain containing 4 1.459
RIPK2 receptor-interacting serine-threonine kinase 2 1.457
NOD1 nucleotide-binding oligomerization domain containing 1 1.449
HTRA1 HtrA serine peptidase 1 1.443
TLR4 toll-like receptor 4 1.441
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.436
TFRC transferrin receptor 1.419
BECN1 beclin 1, autophagy related 1.419
TLR9 toll-like receptor 9 1.418
WASL Wiskott-Aldrich syndrome-like 1.414
ABI1 abl-interactor 1 1.405
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 1.394
IL4 interleukin 4 1.392
ANK2 ankyrin 2, neuronal 1.382
ANK1 ankyrin 1, erythrocytic 1.376
PXDN peroxidasin 1.365
PXDNL peroxidasin-like 1.36
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.359
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 1.358
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 1.345
BCL2A1 BCL2-related protein A1 1.331
VAMP4 vesicle-associated membrane protein 4 1.319
F2 coagulation factor II (thrombin) 1.31
KLHL12 kelch-like family member 12 1.309
PRF1 perforin 1 (pore forming protein) 1.305
KRTAP26-1 keratin associated protein 26-1 1.3
BAHD1 bromo adjacent homology domain containing 1 1.3
LAMP1 lysosomal-associated membrane protein 1 1.296
S100A8 S100 calcium binding protein A8 1.292
DNAH8 dynein, axonemal, heavy chain 8 1.29
ACTB actin, beta 1.27
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 1.27
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 1.268
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 1.262
CCL2 chemokine (C-C motif) ligand 2 1.261
IL2 interleukin 2 1.26
MATK megakaryocyte-associated tyrosine kinase 1.259
NLRP12 NLR family, pyrin domain containing 12 1.258
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.243
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 1.241
YBX3 Y box binding protein 3 1.236
DAZAP2 DAZ associated protein 2 1.227
SPI1 Spi-1 proto-oncogene 1.226
IFNB1 interferon, beta 1, fibroblast 1.225
VDAC1 voltage-dependent anion channel 1 1.221
CCKAR cholecystokinin A receptor 1.217
CCL3 chemokine (C-C motif) ligand 3 1.214
TBL1X transducin (beta)-like 1X-linked 1.212
NLRP1 NLR family, pyrin domain containing 1 1.207
CCT7 chaperonin containing TCP1, subunit 7 (eta) 1.204
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 1.204
RAB10 RAB10, member RAS oncogene family 1.195
GPT2 glutamic pyruvate transaminase (alanine aminotransferase) 2 1.193
CYCS cytochrome c, somatic 1.192
CCL4 chemokine (C-C motif) ligand 4 1.188
TP53I11 tumor protein p53 inducible protein 11 1.188
CD1D CD1d molecule 1.184
IRF7 interferon regulatory factor 7 1.183
SELL selectin L 1.178
CR2 complement component (3d/Epstein Barr virus) receptor 2 1.175
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 1.171
TLR7 toll-like receptor 7 1.171
ANKRD33B ankyrin repeat domain 33B 1.17
HDAC1 histone deacetylase 1 1.155
FZD5 frizzled class receptor 5 1.154
AIM2 absent in melanoma 2 1.151
TLR3 toll-like receptor 3 1.145
RAB14 RAB14, member RAS oncogene family 1.14
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 1.14
SNX11 sorting nexin 11 1.14
BIRC3 baculoviral IAP repeat containing 3 1.134
IL1R1 interleukin 1 receptor, type I 1.125
FTL ferritin, light polypeptide 1.114
GABARAPL2 GABA(A) receptor-associated protein-like 2 1.111
CCL5 chemokine (C-C motif) ligand 5 1.11
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.108
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.106
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 1.106
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 1.104
TNNI3 troponin I type 3 (cardiac) 1.102
TLR1 toll-like receptor 1 1.099
PNLIP pancreatic lipase 1.098
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 1.098
TXN thioredoxin 1.094
IFNA1 interferon, alpha 1 1.091
IRF2BP2 interferon regulatory factor 2 binding protein 2 1.086
GABARAPL1 GABA(A) receptor-associated protein like 1 1.082
CLTCL1 clathrin, heavy chain-like 1 1.079
LCK LCK proto-oncogene, Src family tyrosine kinase 1.078
NPC1 Niemann-Pick disease, type C1 1.077
CXCL13 chemokine (C-X-C motif) ligand 13 1.071
ACTG1 actin gamma 1 1.07
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 1.069
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 1.068
SAMM50 SAMM50 sorting and assembly machinery component 1.065
CLTC clathrin, heavy chain (Hc) 1.062
ATG5 autophagy related 5 1.062
IER3 immediate early response 3 1.061
SLAMF1 signaling lymphocytic activation molecule family member 1 1.05
MED7 mediator complex subunit 7 1.05
WAS Wiskott-Aldrich syndrome 1.05
CXCL9 chemokine (C-X-C motif) ligand 9 1.047
CBS cystathionine-beta-synthase 1.047
CXCL10 chemokine (C-X-C motif) ligand 10 1.045
EPS8L3 EPS8-like 3 1.043
PON1 paraoxonase 1 1.043
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 1.042
CKMT1B creatine kinase, mitochondrial 1B 1.041
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.039
LMLN leishmanolysin-like (metallopeptidase M8 family) 1.039
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 1.039
CKB creatine kinase, brain 1.038
CD48 CD48 molecule 1.037
CKM creatine kinase, muscle 1.036
STAT1 signal transducer and activator of transcription 1, 91kDa 1.034
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.033
SYTL1 synaptotagmin-like 1 1.031
CSF3 colony stimulating factor 3 (granulocyte) 1.027
PMCH pro-melanin-concentrating hormone 1.026
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.025
SEPTIN7 septin 7 1.022
UNC93B1 unc-93 homolog B1 (C. elegans) 1.019
UNC13D unc-13 homolog D (C. elegans) 1.014
B3GAT1 beta-1,3-glucuronyltransferase 1 1.011
CAV1 caveolin 1, caveolae protein, 22kDa 1.01
CTSL cathepsin L 1.009
IRF9 interferon regulatory factor 9 1.008
CALR calreticulin 1.007
RASA1 RAS p21 protein activator (GTPase activating protein) 1 1.007
DEFB4A defensin, beta 4A 1.006
MAPK1 mitogen-activated protein kinase 1 1.004
PHF8 PHD finger protein 8 1.002