| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0520889 |
| CCN2 | cellular communication network factor 2 | 0.0324798 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0274812 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.026991 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0265855 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0247435 |
| CCDC88A | coiled-coil domain containing 88A | 0.0244747 |
| PFN1 | profilin 1 | 0.0213757 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0209847 |
| PLK2 | polo-like kinase 2 | 0.0206161 |
| PRKCI | protein kinase C, iota | 0.0191661 |
| CENPF | centromere protein F, 350/400kDa | 0.0191033 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0188842 |
| EDN1 | endothelin 1 | 0.0175656 |
| TPM3 | tropomyosin 3 | 0.0167455 |
| RPL3 | ribosomal protein L3 | 0.016647 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0164203 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0162364 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0159594 |
| CCNL1 | cyclin L1 | 0.0158111 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0158014 |
| TPI1 | triosephosphate isomerase 1 | 0.015582 |
| RTN4 | reticulon 4 | 0.015437 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0154339 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0153208 |
| WDR43 | WD repeat domain 43 | 0.0149728 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0146612 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0143683 |
| XPO1 | exportin 1 | 0.0140578 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0139761 |
| KIF5B | kinesin family member 5B | 0.013935 |
| PCM1 | pericentriolar material 1 | 0.0138595 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0138144 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0137257 |
| HLTF | helicase-like transcription factor | 0.0135218 |
| LOC112694756 | uncharaterized LOC112694756 | 0.013447 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0129403 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.012919 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0128468 |
| ZNF292 | zinc finger protein 292 | 0.0126821 |
| CEP70 | centrosomal protein 70kDa | 0.0126564 |
| DST | dystonin | 0.0125701 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0125394 |
| EZR | ezrin | 0.0124803 |
| PLEC | plectin | 0.0122641 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0122176 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.012205 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0122023 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0121926 |
| PNN | pinin, desmosome associated protein | 0.0118749 |
| RNF145 | ring finger protein 145 | 0.0118258 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0118098 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0118031 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.011772 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0117247 |
| FASN | fatty acid synthase | 0.0116877 |
| RPL35A | ribosomal protein L35a | 0.0112572 |
| SON | SON DNA binding protein | 0.0111289 |
| ERBIN | erbb2 interacting protein | 0.0110313 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0109185 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0108765 |
| MSN | moesin | 0.0107822 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0104796 |
| HMGA1 | high mobility group AT-hook 1 | 0.0104258 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0104033 |
| FLNA | filamin A, alpha | 0.0104025 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0103829 |
| CEP250 | centrosomal protein 250kDa | 0.0103485 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0103459 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0102929 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0102009 |
| PPID | peptidylprolyl isomerase D | 0.00993415 |
| TGM2 | transglutaminase 2 | 0.0098432 |
| MBD6 | methyl-CpG binding domain protein 6 | 0.00980774 |
| YBX3 | Y box binding protein 3 | 0.00979581 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.009742 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00970018 |
| PTEN | phosphatase and tensin homolog | 0.00968668 |
| TSPAN5 | tetraspanin 5 | 0.00966306 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.00955192 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00950618 |
| REPS1 | RALBP1 associated Eps domain containing 1 | 0.00950583 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0094873 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.00945089 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.00943797 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00941426 |
| HLA-A | major histocompatibility complex, class I, A | 0.00938069 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0093682 |
| THOC2 | THO complex 2 | 0.00936282 |
| YTHDC1 | YTH domain containing 1 | 0.00934741 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.00932092 |
| SIRT1 | sirtuin 1 | 0.00931747 |
| CARD16 | caspase recruitment domain family, member 16 | 0.00930668 |
| KIF18B | kinesin family member 18B | 0.00918384 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.00916173 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00913639 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.00909437 |
| KIF1B | kinesin family member 1B | 0.00900568 |
| CLDND1 | claudin domain containing 1 | 0.00889233 |
| YBX1 | Y box binding protein 1 | 0.00886869 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.278306 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.17852 |
| VIM | vimentin | -0.165475 |
| HMGA2 | high mobility group AT-hook 2 | -0.132153 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.129533 |
| NLGN1 | neuroligin 1 | -0.101604 |
| TMSB10 | thymosin beta 10 | -0.0907 |
| ASPH | aspartate beta-hydroxylase | -0.0830625 |
| MMP12 | matrix metallopeptidase 12 | -0.0806985 |
| YAP1 | Yes-associated protein 1 | -0.07731 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0749014 |
| RPS27A | ribosomal protein S27a | -0.0732189 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0692013 |
| PTMA | prothymosin, alpha | -0.0648537 |
| UBC | ubiquitin C | -0.0644049 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0625423 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0612379 |
| PCDH7 | protocadherin 7 | -0.0596016 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0592495 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0584639 |
| EHBP1 | EH domain binding protein 1 | -0.0580599 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0500362 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0498283 |
| NHSL1 | NHS-like 1 | -0.049656 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.049242 |
| ZNF804A | zinc finger protein 804A | -0.0490266 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0487465 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0477449 |
| CANX | calnexin | -0.0476569 |
| BCHE | butyrylcholinesterase | -0.0476147 |
| AHNAK | AHNAK nucleoprotein | -0.0472476 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0470277 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0461444 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0457173 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0448809 |
| JMJD1C | jumonji domain containing 1C | -0.0447505 |
| INTS6 | integrator complex subunit 6 | -0.0417852 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0417091 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0403839 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0403411 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0401139 |
| ADIPOR2 | adiponectin receptor 2 | -0.0398988 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0392551 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0373436 |
| MTAP | methylthioadenosine phosphorylase | -0.0361125 |
| RPL23 | ribosomal protein L23 | -0.035919 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0353356 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0351348 |
| RPS24 | ribosomal protein S24 | -0.0325546 |
| PCDH9 | protocadherin 9 | -0.03132 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0307424 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0306194 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0298283 |
| ANXA1 | annexin A1 | -0.0291254 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0290463 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0288567 |
| RAB10 | RAB10, member RAS oncogene family | -0.0285261 |
| RRM2 | ribonucleotide reductase M2 | -0.0284816 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0279075 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0277772 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0276482 |
| RPS8 | ribosomal protein S8 | -0.0269657 |
| VMP1 | vacuole membrane protein 1 | -0.0265144 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0264876 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0264421 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0262562 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0258045 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0257206 |
| CUX1 | cut-like homeobox 1 | -0.0255962 |
| ACTG1 | actin gamma 1 | -0.0252447 |
| HDAC9 | histone deacetylase 9 | -0.0251405 |
| VCL | vinculin | -0.0250591 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0247256 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0244693 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0244504 |
| RPLP0 | ribosomal protein, large, P0 | -0.0243459 |
| S100A10 | S100 calcium binding protein A10 | -0.0237306 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0236474 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0235943 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0235716 |
| RPS15 | ribosomal protein S15 | -0.0235375 |
| ZNF217 | zinc finger protein 217 | -0.0234704 |
| ENO1 | enolase 1, (alpha) | -0.0230137 |
| CALR | calreticulin | -0.0229699 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0228848 |
| MYPN | myopalladin | -0.0228698 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0227277 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0223884 |
| COMMD10 | COMM domain containing 10 | -0.0223583 |
| DENND5A | DENN/MADD domain containing 5A | -0.0223442 |
| USP53 | ubiquitin specific peptidase 53 | -0.0223115 |
| LRRC23 | leucine rich repeat containing 23 | -0.0222973 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0222575 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | -0.0222086 |
| RPLP2 | ribosomal protein, large, P2 | -0.0221413 |
| PDGFC | platelet derived growth factor C | -0.0220005 |
| RPL26 | ribosomal protein L26 | -0.0219862 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0218687 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0218595 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0217822 |
