| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC112694756 | uncharaterized LOC112694756 | 0.0819771 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0796007 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0769661 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0730641 |
| NAV2 | neuron navigator 2 | 0.0660295 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0654415 |
| INTS6 | integrator complex subunit 6 | 0.0649206 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0649064 |
| SMAD3 | SMAD family member 3 | 0.0641182 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0634437 |
| FLNA | filamin A, alpha | 0.0612558 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0572341 |
| PLEC | plectin | 0.0550684 |
| ACTG1 | actin gamma 1 | 0.0496711 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0479995 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0462512 |
| TLE4 | transducin-like enhancer of split 4 | 0.0450855 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0448365 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0440004 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0428047 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0421912 |
| PALLD | palladin, cytoskeletal associated protein | 0.0418435 |
| RNF213 | ring finger protein 213 | 0.041787 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0416896 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0406037 |
| LMNA | lamin A/C | 0.0391707 |
| RPS4X | ribosomal protein S4, X-linked | 0.0389505 |
| UBAP2 | ubiquitin associated protein 2 | 0.0377358 |
| RPS2 | ribosomal protein S2 | 0.0374896 |
| GOLGB1 | golgin B1 | 0.0371464 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0363688 |
| LDHA | lactate dehydrogenase A | 0.0363227 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0359754 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.035315 |
| SUCO | SUN domain containing ossification factor | 0.0351227 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0347712 |
| NDRG1 | N-myc downstream regulated 1 | 0.0346069 |
| CRY1 | cryptochrome circadian clock 1 | 0.0344129 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0343624 |
| POTEF | POTE ankyrin domain family, member F | 0.0338981 |
| VEGFA | vascular endothelial growth factor A | 0.0336756 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.033445 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0333695 |
| ACTN1 | actinin, alpha 1 | 0.0333695 |
| ATF3 | activating transcription factor 3 | 0.032647 |
| CTBP2 | C-terminal binding protein 2 | 0.0323227 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0318915 |
| SURF4 | surfeit 4 | 0.0317404 |
| SEPTIN9 | septin 9 | 0.0316373 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0315848 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.03149 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0313121 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0307621 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0305414 |
| NUP98 | nucleoporin 98kDa | 0.0303296 |
| FHL2 | four and a half LIM domains 2 | 0.0295733 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0295075 |
| LYST | lysosomal trafficking regulator | 0.0294486 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.02938 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0292984 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0286194 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0282572 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0276807 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0271886 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0269017 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0267789 |
| KYNU | kynureninase | 0.0266979 |
| TUT7 | terminal uridylyl transferase 7 | 0.026236 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0255706 |
| PGM3 | phosphoglucomutase 3 | 0.0255208 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0253395 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0252742 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0251879 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0251619 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0247818 |
| MCL1 | myeloid cell leukemia 1 | 0.0245521 |
| RPS20 | ribosomal protein S20 | 0.0244434 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0243756 |
| GPATCH2L | G patch domain containing 2-like | 0.0243712 |
| SPAG9 | sperm associated antigen 9 | 0.0241549 |
| HDLBP | high density lipoprotein binding protein | 0.0240484 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0240366 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0239481 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | 0.0238955 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0237096 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0232353 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0230684 |
| ACTN4 | actinin, alpha 4 | 0.022989 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0227404 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0227119 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0226223 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | 0.0226037 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0225934 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0223256 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0222834 |
| TLN1 | talin 1 | 0.0219715 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0217722 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0216712 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0215971 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0213044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.145971 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0978186 |
| PTMA | prothymosin, alpha | -0.0898915 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0895103 |
| MAP1B | microtubule-associated protein 1B | -0.0851809 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0807287 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0765001 |
| CP | ceruloplasmin (ferroxidase) | -0.0706053 |
| RAI14 | retinoic acid induced 14 | -0.0702087 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0686248 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0674921 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0614005 |
| VIM | vimentin | -0.0599779 |
| FRMD4A | FERM domain containing 4A | -0.059895 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0591002 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.057111 |
| GPC6 | glypican 6 | -0.0549783 |
| CD44 | CD44 molecule (Indian blood group) | -0.0494374 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0473759 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0463793 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0455868 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0451019 |
| RPS6 | ribosomal protein S6 | -0.0433795 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0430005 |
| TMSB10 | thymosin beta 10 | -0.0420766 |
| RPS24 | ribosomal protein S24 | -0.0418913 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0409252 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0400805 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0393016 |
| TXNRD1 | thioredoxin reductase 1 | -0.0382717 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0382681 |
| SBF2 | SET binding factor 2 | -0.0368623 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0367358 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0360997 |
| TRAM1 | translocation associated membrane protein 1 | -0.0360693 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0352159 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0350242 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.034873 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0341632 |
| PLIN2 | perilipin 2 | -0.0339204 |
| MPZL1 | myelin protein zero-like 1 | -0.0336356 |
| ANLN | anillin, actin binding protein | -0.0334351 |
| TRIM56 | tripartite motif containing 56 | -0.0329216 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0326526 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0325183 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0323177 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0322657 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0320984 |
| CDCP1 | CUB domain containing protein 1 | -0.032004 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0316384 |
| HLA-B | major histocompatibility complex, class I, B | -0.0315781 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.0314538 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0313538 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0305876 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0304584 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0300325 |
| PGK1 | phosphoglycerate kinase 1 | -0.0296532 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0296184 |
| MMP7 | matrix metallopeptidase 7 | -0.0291623 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0287762 |
| CBX3 | chromobox homolog 3 | -0.0285214 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.02845 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0282236 |
| ATP13A3 | ATPase type 13A3 | -0.0279129 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.027739 |
| PTGR1 | prostaglandin reductase 1 | -0.0277107 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0277019 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0275602 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.027474 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0273627 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.027268 |
| ITGAV | integrin, alpha V | -0.0272482 |
| DIAPH3 | diaphanous-related formin 3 | -0.0272264 |
| CALD1 | caldesmon 1 | -0.0271615 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0267914 |
| SP3 | Sp3 transcription factor | -0.0259753 |
| MT2A | metallothionein 2A | -0.0259735 |
| RTN4 | reticulon 4 | -0.0258034 |
| DIAPH2 | diaphanous-related formin 2 | -0.025638 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0255893 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.0253297 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0251393 |
| AZIN1 | antizyme inhibitor 1 | -0.0248326 |
| PRKD3 | protein kinase D3 | -0.024703 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0246931 |
| STK17A | serine/threonine kinase 17a | -0.0246565 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0244736 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0244624 |
| AHNAK | AHNAK nucleoprotein | -0.024439 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0243545 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | -0.0240804 |
| CADM1 | cell adhesion molecule 1 | -0.0240438 |
| ADAR | adenosine deaminase, RNA-specific | -0.0239903 |
| TMEM165 | transmembrane protein 165 | -0.0239511 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0236374 |
| MKI67 | marker of proliferation Ki-67 | -0.0235743 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0235678 |
| ETV6 | ets variant 6 | -0.0233483 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.023211 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0231837 |
