| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.144813 |
| NDRG1 | N-myc downstream regulated 1 | 0.0853384 |
| EGFR | epidermal growth factor receptor | 0.0822568 |
| ACTG1 | actin gamma 1 | 0.0754753 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0623676 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0603304 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0581801 |
| EFNA5 | ephrin-A5 | 0.0557574 |
| MCL1 | myeloid cell leukemia 1 | 0.0507839 |
| STC1 | stanniocalcin 1 | 0.0473409 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0465194 |
| HMGA2 | high mobility group AT-hook 2 | 0.0447695 |
| VIM | vimentin | 0.0422028 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0415088 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0405723 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.03713 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0367923 |
| TNS1 | tensin 1 | 0.0362203 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0357391 |
| EGR1 | early growth response 1 | 0.0343638 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0333594 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | 0.0317871 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0314799 |
| PYGL | phosphorylase, glycogen, liver | 0.0311094 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0301194 |
| CCDC88A | coiled-coil domain containing 88A | 0.0297592 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0291398 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0280295 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.026679 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0264258 |
| AXL | AXL receptor tyrosine kinase | 0.0262694 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.025991 |
| POTEF | POTE ankyrin domain family, member F | 0.0257298 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0256978 |
| AADAC | arylacetamide deacetylase | 0.0244643 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0243001 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0232871 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0228433 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0225606 |
| VEGFA | vascular endothelial growth factor A | 0.0213166 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0213121 |
| MYO1E | myosin IE | 0.0212622 |
| LAMC2 | laminin, gamma 2 | 0.0212103 |
| OPTN | optineurin | 0.020894 |
| MYO9A | myosin IXA | 0.020511 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0203654 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0203283 |
| DAPK1 | death-associated protein kinase 1 | 0.0195863 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0192516 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0192432 |
| RAD51B | RAD51 paralog B | 0.0191085 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0190899 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.018902 |
| FN1 | fibronectin 1 | 0.0185123 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.018301 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0182114 |
| ANXA2 | annexin A2 | 0.0181914 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0180849 |
| FBXO17 | F-box protein 17 | 0.0180343 |
| LAMA5 | laminin, alpha 5 | 0.0177764 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0177299 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0176744 |
| CD68 | CD68 molecule | 0.0174521 |
| MSN | moesin | 0.0174159 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0173748 |
| SETX | senataxin | 0.0173472 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0171173 |
| RPS12 | ribosomal protein S12 | 0.0171144 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.016735 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0166842 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0165815 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0164549 |
| RPL37A | ribosomal protein L37a | 0.016147 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0160912 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0158 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0155569 |
| RPS2 | ribosomal protein S2 | 0.0155117 |
| DOCK5 | dedicator of cytokinesis 5 | 0.015495 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0154674 |
| RACK1 | receptor for activated C kinase 1 | 0.0154472 |
| BPTF | bromodomain PHD finger transcription factor | 0.0154217 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0152872 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0152442 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0150354 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0150049 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0149576 |
| CREBBP | CREB binding protein | 0.0149064 |
| ITGB4 | integrin, beta 4 | 0.0148161 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0146759 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0146062 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0144907 |
| MAP7 | microtubule-associated protein 7 | 0.0144426 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0143002 |
| INTS6 | integrator complex subunit 6 | 0.0142358 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0134166 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0133328 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0132388 |
| FAT1 | FAT atypical cadherin 1 | 0.0130655 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0130562 |
| PRKCE | protein kinase C, epsilon | 0.0129476 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.220664 |
| FTL | ferritin, light polypeptide | -0.148498 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.136432 |
| USP3 | ubiquitin specific peptidase 3 | -0.113581 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.103505 |
| PTMA | prothymosin, alpha | -0.0975468 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0926087 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0904673 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0878259 |
| MT2A | metallothionein 2A | -0.0870322 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0843933 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0838143 |
| SPAG9 | sperm associated antigen 9 | -0.0825379 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0769071 |
| HELZ | helicase with zinc finger | -0.0755665 |
| TXNRD1 | thioredoxin reductase 1 | -0.0724558 |
| MT1X | metallothionein 1X | -0.0700976 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0653546 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0626901 |
| PGK1 | phosphoglycerate kinase 1 | -0.0617669 |
| TMSB10 | thymosin beta 10 | -0.0615064 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0603576 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.059774 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0592986 |
| GOLGA4 | golgin A4 | -0.0592143 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.05843 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0567918 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0556609 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0553473 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0550633 |
| TKT | transketolase | -0.0526578 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.051262 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0508141 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0497868 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.049252 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0489505 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0482582 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0474476 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0467243 |
| ECT2 | epithelial cell transforming 2 | -0.0465726 |
| RPS19 | ribosomal protein S19 | -0.0463248 |
| VMP1 | vacuole membrane protein 1 | -0.0460587 |
| CANX | calnexin | -0.0455984 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0449938 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.044924 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0448355 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0446789 |
| AHNAK | AHNAK nucleoprotein | -0.0444113 |
| OGA | O-GlcNAcase | -0.0437776 |
| UBC | ubiquitin C | -0.0432602 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0429159 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0428991 |
| RRBP1 | ribosome binding protein 1 | -0.042898 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0423823 |
| SBF2 | SET binding factor 2 | -0.0417074 |
| PARD3 | par-3 family cell polarity regulator | -0.0406699 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.040527 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0404217 |
| RPS24 | ribosomal protein S24 | -0.0401777 |
| RPLP1 | ribosomal protein, large, P1 | -0.0401254 |
| RPS6 | ribosomal protein S6 | -0.0393112 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.038483 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0383314 |
| DENND4C | DENN/MADD domain containing 4C | -0.0375639 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0373925 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0371606 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.03709 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0366762 |
| EREG | epiregulin | -0.0365264 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0363842 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0363492 |
| OLA1 | Obg-like ATPase 1 | -0.0359423 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0356639 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0356326 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0354718 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0351413 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0349395 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0346825 |
| NUP58 | nucleoporin 58 | -0.0346221 |
| RBM39 | RNA binding motif protein 39 | -0.0345551 |
| FMNL2 | formin-like 2 | -0.0345213 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0345145 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0339489 |
| USP34 | ubiquitin specific peptidase 34 | -0.0338032 |
| WAC | WW domain containing adaptor with coiled-coil | -0.033803 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0337525 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0336961 |
| KLF6 | Kruppel-like factor 6 | -0.0335668 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0334267 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0334055 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0332707 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0332439 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0332373 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0328432 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0323876 |
| S100A10 | S100 calcium binding protein A10 | -0.0322352 |
| CMIP | c-Maf inducing protein | -0.0321683 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0320827 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0319437 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0317233 |
