| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.187435 |
| EGFR | epidermal growth factor receptor | 0.0936041 |
| EFNA5 | ephrin-A5 | 0.0559875 |
| PLEC | plectin | 0.0458806 |
| SMAD3 | SMAD family member 3 | 0.0441311 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0383211 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0315632 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0291623 |
| LOC112694756 | uncharaterized LOC112694756 | 0.027126 |
| TGM2 | transglutaminase 2 | 0.0261123 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0253377 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0247222 |
| HMGA2 | high mobility group AT-hook 2 | 0.024496 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0242623 |
| SEPTIN9 | septin 9 | 0.0239901 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.023257 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0231229 |
| BMP6 | bone morphogenetic protein 6 | 0.0228856 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0227776 |
| NDRG1 | N-myc downstream regulated 1 | 0.0225907 |
| DOCK5 | dedicator of cytokinesis 5 | 0.02246 |
| MCL1 | myeloid cell leukemia 1 | 0.0220639 |
| INTS6 | integrator complex subunit 6 | 0.0217588 |
| PMM2 | phosphomannomutase 2 | 0.019102 |
| FLNA | filamin A, alpha | 0.0185841 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.017797 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0177142 |
| HLA-C | major histocompatibility complex, class I, C | 0.0175238 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0173151 |
| RUNX1 | runt-related transcription factor 1 | 0.016605 |
| CLMP | CXADR-like membrane protein | 0.0165169 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0164591 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0162492 |
| RNF213 | ring finger protein 213 | 0.0158156 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0156258 |
| MT2A | metallothionein 2A | 0.0155462 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0151849 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0149273 |
| FMNL2 | formin-like 2 | 0.0145839 |
| LAMA5 | laminin, alpha 5 | 0.014096 |
| PITPNM2 | phosphatidylinositol transfer protein, membrane-associated 2 | 0.0140616 |
| ATXN1 | ataxin 1 | 0.0140204 |
| ATXN2L | ataxin 2-like | 0.013886 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0138695 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0138693 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.01368 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0134036 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0133961 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0132615 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0130264 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.012657 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0125738 |
| TMC5 | transmembrane channel-like 5 | 0.0124615 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0123847 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0122072 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.0119287 |
| CUL4A | cullin 4A | 0.0117345 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.011541 |
| FN1 | fibronectin 1 | 0.0114795 |
| MYO19 | myosin XIX | 0.0113799 |
| LOXL2 | lysyl oxidase-like 2 | 0.0113124 |
| BRD2 | bromodomain containing 2 | 0.0113006 |
| VKORC1L1 | vitamin K epoxide reductase complex, subunit 1-like 1 | 0.0111763 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0111405 |
| UBE3C | ubiquitin protein ligase E3C | 0.0107404 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0106759 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit | 0.0105696 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0105565 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0104105 |
| SEC24C | SEC24 family member C | 0.0103639 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0103599 |
| DNM2 | dynamin 2 | 0.0103502 |
| GSPT1 | G1 to S phase transition 1 | 0.0103244 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0103138 |
| ANTXR2 | anthrax toxin receptor 2 | 0.010285 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.010155 |
| ATG7 | autophagy related 7 | 0.0101364 |
| NECTIN1 | nectin cell adhesion molecule 1 | 0.0101158 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0100874 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00989615 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.009892 |
| AEBP2 | AE binding protein 2 | 0.00987378 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00975085 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.00967405 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.00960935 |
| NRDC | nardilysin convertase | 0.00960432 |
| POU2F2 | POU class 2 homeobox 2 | 0.0095704 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0095303 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00950619 |
| SURF4 | surfeit 4 | 0.00934962 |
| CLMN | calmin (calponin-like, transmembrane) | 0.00934881 |
| SAFB2 | scaffold attachment factor B2 | 0.00931012 |
| MX1 | MX dynamin-like GTPase 1 | 0.009297 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0092691 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.00907901 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.00907566 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0090714 |
| NIBAN2 | niban apoptosis regulator 2 | 0.00904571 |
| SMYD3 | SET and MYND domain containing 3 | 0.00903496 |
| PRELID2 | PRELI domain containing 2 | 0.00900054 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.219939 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.160167 |
| KLK10 | kallikrein-related peptidase 10 | -0.127341 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.126996 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.11599 |
| LAMC2 | laminin, gamma 2 | -0.114589 |
| UBC | ubiquitin C | -0.108563 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.108528 |
| TMSB10 | thymosin beta 10 | -0.105673 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.100791 |
| POTEF | POTE ankyrin domain family, member F | -0.0982914 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0915241 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0878457 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0865276 |
| RIOK3 | RIO kinase 3 | -0.0856782 |
| PTMA | prothymosin, alpha | -0.0845046 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0785114 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0759526 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0743578 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0737188 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0732235 |
| LMO7 | LIM domain 7 | -0.0715152 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0714336 |
| S100A10 | S100 calcium binding protein A10 | -0.0713938 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0697342 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0695269 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0688483 |
| VIM | vimentin | -0.0685937 |
| LAMB3 | laminin, beta 3 | -0.0685773 |
| HMGA1 | high mobility group AT-hook 1 | -0.0663454 |
| DSG2 | desmoglein 2 | -0.0641716 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0619569 |
| ASPH | aspartate beta-hydroxylase | -0.0613497 |
| PGK1 | phosphoglycerate kinase 1 | -0.0584267 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0583264 |
| SPAG9 | sperm associated antigen 9 | -0.0578864 |
| PARD3 | par-3 family cell polarity regulator | -0.0574616 |
| TXNIP | thioredoxin interacting protein | -0.0561729 |
| ITGA6 | integrin, alpha 6 | -0.0552832 |
| SLMAP | sarcolemma associated protein | -0.0547181 |
| PERP | PERP, TP53 apoptosis effector | -0.0541178 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0540805 |
| TXNRD1 | thioredoxin reductase 1 | -0.0535637 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0522079 |
| MXD1 | MAX dimerization protein 1 | -0.0513168 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0502496 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0496569 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0487908 |
| LDHA | lactate dehydrogenase A | -0.0483538 |
| LAMA4 | laminin, alpha 4 | -0.0477515 |
| RAB7A | RAB7A, member RAS oncogene family | -0.046493 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0461019 |
| UPP1 | uridine phosphorylase 1 | -0.0449355 |
| PRSS3 | protease, serine, 3 | -0.0445053 |
| RPS2 | ribosomal protein S2 | -0.0440427 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0438153 |
| S100A6 | S100 calcium binding protein A6 | -0.0438062 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0433727 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0431877 |
| SNX9 | sorting nexin 9 | -0.0422569 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0414995 |
| TPM4 | tropomyosin 4 | -0.0414874 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0409683 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0406189 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0405476 |
| CORO1C | coronin, actin binding protein, 1C | -0.0405417 |
| SBF2 | SET binding factor 2 | -0.0402706 |
| MUC17 | mucin 17, cell surface associated | -0.0398088 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0391415 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0385583 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0385282 |
| CAB39 | calcium binding protein 39 | -0.038512 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.038258 |
| B2M | beta-2-microglobulin | -0.0382211 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0381429 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0379096 |
| RPL8 | ribosomal protein L8 | -0.0375476 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0373476 |
| DIAPH2 | diaphanous-related formin 2 | -0.0372358 |
| RPL12 | ribosomal protein L12 | -0.0367384 |
| RBM39 | RNA binding motif protein 39 | -0.0366105 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0365368 |
| EZR | ezrin | -0.0364016 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0363817 |
| RTN4 | reticulon 4 | -0.0363558 |
| NPSR1 | neuropeptide S receptor 1 | -0.0363456 |
| S100A11 | S100 calcium binding protein A11 | -0.0361153 |
| AHNAK | AHNAK nucleoprotein | -0.0359415 |
| EMP1 | epithelial membrane protein 1 | -0.0358925 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0357416 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.035556 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0355437 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0354947 |
| CALU | calumenin | -0.035383 |
| OPTN | optineurin | -0.035251 |
| GOLGA4 | golgin A4 | -0.0352065 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0348627 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0344811 |
| WASF2 | WAS protein family, member 2 | -0.034326 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0342999 |
