| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NEBL | nebulette | 0.0681712 |
| ATP11A | ATPase, class VI, type 11A | 0.0520037 |
| HSPA8 | heat shock 70kDa protein 8 | 0.048732 |
| ACTG1 | actin gamma 1 | 0.0469435 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0428417 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0320528 |
| ZNF608 | zinc finger protein 608 | 0.0317779 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0282803 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0275104 |
| MLIP | muscular LMNA-interacting protein | 0.0266664 |
| CNN2 | calponin 2 | 0.0263321 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.0261909 |
| RCC1 | regulator of chromosome condensation 1 | 0.0259362 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.02292 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0228005 |
| SMC1A | structural maintenance of chromosomes 1A | 0.02149 |
| WLS | wntless Wnt ligand secretion mediator | 0.0208225 |
| RPL13A | ribosomal protein L13a | 0.0206889 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0200178 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0199674 |
| RPS3 | ribosomal protein S3 | 0.0197255 |
| UBAP2 | ubiquitin associated protein 2 | 0.0196412 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0194141 |
| BRD2 | bromodomain containing 2 | 0.0193938 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0187075 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0185941 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0185855 |
| RRM2 | ribonucleotide reductase M2 | 0.0185428 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0182815 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0180768 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.017473 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0172682 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0172589 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0170741 |
| GSE1 | Gse1 coiled-coil protein | 0.0168786 |
| BRD9 | bromodomain containing 9 | 0.0166955 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0165845 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.015663 |
| PLCG1 | phospholipase C, gamma 1 | 0.015264 |
| NID1 | nidogen 1 | 0.0152519 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0152441 |
| RPL37A | ribosomal protein L37a | 0.0149259 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0149239 |
| RPL35A | ribosomal protein L35a | 0.0148821 |
| GPATCH2L | G patch domain containing 2-like | 0.0147565 |
| DENND1A | DENN/MADD domain containing 1A | 0.0146812 |
| SRRT | serrate, RNA effector molecule | 0.0145637 |
| RABL6 | RAB, member RAS oncogene family-like 6 | 0.0145572 |
| WDR1 | WD repeat domain 1 | 0.0145376 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0145016 |
| PABPC1L | poly(A) binding protein, cytoplasmic 1-like | 0.0143353 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0142938 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0142433 |
| RPL41 | ribosomal protein L41 | 0.0140537 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0140001 |
| RBM28 | RNA binding motif protein 28 | 0.0138292 |
| GRIPAP1 | GRIP1 associated protein 1 | 0.0138056 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0137384 |
| HIRA | histone cell cycle regulator | 0.0137302 |
| MSH4 | mutS homolog 4 | 0.0137221 |
| PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | 0.013595 |
| VCL | vinculin | 0.0135598 |
| WDR27 | WD repeat domain 27 | 0.0135029 |
| CREB1 | cAMP responsive element binding protein 1 | 0.0133981 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0133534 |
| MBTD1 | mbt domain containing 1 | 0.0133153 |
| PDZD8 | PDZ domain containing 8 | 0.0130721 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0130128 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0129461 |
| PSEN1 | presenilin 1 | 0.0129457 |
| LRRC41 | leucine rich repeat containing 41 | 0.012931 |
| EXOC4 | exocyst complex component 4 | 0.0129108 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0129079 |
| ALMS1 | Alstrom syndrome protein 1 | 0.0127902 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0127731 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | 0.0127545 |
| LAMA5 | laminin, alpha 5 | 0.0126876 |
| ATG7 | autophagy related 7 | 0.0125656 |
| TENM2 | teneurin transmembrane protein 2 | 0.0124683 |
| KLHL29 | kelch-like family member 29 | 0.0124533 |
| DOCK3 | dedicator of cytokinesis 3 | 0.0124498 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A | 0.0123404 |
| WDR33 | WD repeat domain 33 | 0.012259 |
| ELFN1 | extracellular leucine-rich repeat and fibronectin type III domain containing 1 | 0.0121253 |
| NUP98 | nucleoporin 98kDa | 0.0119955 |
| PMM2 | phosphomannomutase 2 | 0.0119075 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.0118913 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0118532 |
| SMAD4 | SMAD family member 4 | 0.0118083 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0117876 |
| ARHGAP39 | Rho GTPase activating protein 39 | 0.0117698 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0117691 |
| EMC10 | ER membrane protein complex subunit 10 | 0.011739 |
| TEAD4 | TEA domain family member 4 | 0.0117173 |
| SMAD6 | SMAD family member 6 | 0.0116506 |
| MNT | MAX network transcriptional repressor | 0.0115661 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0115162 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0114345 |
| TMEM67 | transmembrane protein 67 | 0.0113454 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0112856 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.239547 |
| PTMA | prothymosin, alpha | -0.107656 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.101475 |
| CADM2 | cell adhesion molecule 2 | -0.0872802 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0839621 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0764352 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0738974 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0728977 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0726365 |
| ZNF292 | zinc finger protein 292 | -0.0712239 |
| LDHA | lactate dehydrogenase A | -0.0650858 |
| TOX | thymocyte selection-associated high mobility group box | -0.0606202 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0600201 |
| RPS6 | ribosomal protein S6 | -0.0584153 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0578878 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0577694 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.055632 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0535066 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0533662 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0530282 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0523501 |
| RPL28 | ribosomal protein L28 | -0.0520204 |
| TPD52 | tumor protein D52 | -0.0514659 |
| PGK1 | phosphoglycerate kinase 1 | -0.0510261 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.0507033 |
| QKI | QKI, KH domain containing, RNA binding | -0.0503647 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | -0.0498523 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0494975 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0493221 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.0482755 |
| FMNL2 | formin-like 2 | -0.0477806 |
| PHIP | pleckstrin homology domain interacting protein | -0.0477655 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0476711 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0471617 |
| CDH18 | cadherin 18, type 2 | -0.0460167 |
| RLF | rearranged L-myc fusion | -0.0455766 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0447017 |
| NUP58 | nucleoporin 58 | -0.0442673 |
| HMGB1 | high mobility group box 1 | -0.0437763 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0437188 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0428468 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0425653 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0423477 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0419777 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.041967 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0418562 |
| RPS24 | ribosomal protein S24 | -0.0416447 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0414885 |
| HELZ | helicase with zinc finger | -0.0413165 |
| RPL23 | ribosomal protein L23 | -0.0412053 |
| FAM162A | family with sequence similarity 162, member A | -0.0407769 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0407125 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0407097 |
| NFIA | nuclear factor I/A | -0.0400714 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0397661 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0396326 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.039586 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0391854 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0390726 |
| BBX | bobby sox homolog (Drosophila) | -0.0390712 |
| GNAS | GNAS complex locus | -0.0389312 |
| PTK2 | protein tyrosine kinase 2 | -0.038874 |
| PARD3 | par-3 family cell polarity regulator | -0.0387411 |
| UBC | ubiquitin C | -0.0385636 |
| H1-0 | H1.0 linker histone | -0.0384924 |
| RPS11 | ribosomal protein S11 | -0.0383382 |
| SETD5 | SET domain containing 5 | -0.0382724 |
| RPS21 | ribosomal protein S21 | -0.0378288 |
| KIAA1958 | KIAA1958 | -0.037347 |
| TXNRD1 | thioredoxin reductase 1 | -0.0372358 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0371763 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0367132 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | -0.0359974 |
| USP34 | ubiquitin specific peptidase 34 | -0.0359781 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0357471 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | -0.035608 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0356049 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.03555 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0355275 |
| ZNF638 | zinc finger protein 638 | -0.0355161 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0354884 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0350574 |
| SEPTIN7 | septin 7 | -0.0348819 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0347919 |
| GOLGA4 | golgin A4 | -0.0347194 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0346326 |
| EFNA5 | ephrin-A5 | -0.0345296 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | -0.0342826 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0342782 |
| PCBP2 | poly(rC) binding protein 2 | -0.0342437 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0340215 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0339552 |
| PDE8A | phosphodiesterase 8A | -0.0339283 |
| OGA | O-GlcNAcase | -0.0338672 |
| EGR1 | early growth response 1 | -0.0334479 |
| RPL19 | ribosomal protein L19 | -0.0332412 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0327282 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.032576 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0323169 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0321611 |
