| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.141182 |
| ACTG1 | actin gamma 1 | 0.0505959 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0476516 |
| HLA-C | major histocompatibility complex, class I, C | 0.0438654 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0434091 |
| LOC112694756 | uncharaterized LOC112694756 | 0.040615 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0297523 |
| NDRG1 | N-myc downstream regulated 1 | 0.0256159 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0250179 |
| ARRDC3 | arrestin domain containing 3 | 0.0240758 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0231502 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0229383 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0205244 |
| SMAD3 | SMAD family member 3 | 0.0195016 |
| WDR45B | WD repeat domain 45B | 0.0193818 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0189081 |
| BRD2 | bromodomain containing 2 | 0.0186721 |
| FAM13A | family with sequence similarity 13, member A | 0.0184883 |
| MYOF | myoferlin | 0.0175922 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0161229 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.01605 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0152778 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0150324 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0150249 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0149326 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0148258 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0142994 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.014117 |
| TMEM51 | transmembrane protein 51 | 0.0140825 |
| NUP58 | nucleoporin 58 | 0.0140415 |
| ANXA2 | annexin A2 | 0.0136928 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0136123 |
| RLF | rearranged L-myc fusion | 0.0136003 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0135892 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0134786 |
| HLA-E | major histocompatibility complex, class I, E | 0.013322 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0130156 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0129065 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0126192 |
| YTHDC1 | YTH domain containing 1 | 0.0123956 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0120688 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0117097 |
| OGA | O-GlcNAcase | 0.011605 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0114553 |
| STC1 | stanniocalcin 1 | 0.0114242 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0113749 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0113335 |
| RPLP0 | ribosomal protein, large, P0 | 0.0112729 |
| TOP1 | topoisomerase (DNA) I | 0.0112214 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0111489 |
| EREG | epiregulin | 0.011028 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0109392 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.01091 |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa | 0.0103547 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0100824 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0100209 |
| PCBP2 | poly(rC) binding protein 2 | 0.00980747 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.00972772 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.00958653 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00954825 |
| FNBP4 | formin binding protein 4 | 0.00944126 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.00938814 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0093169 |
| CCNL1 | cyclin L1 | 0.00928498 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00924305 |
| RAB8B | RAB8B, member RAS oncogene family | 0.00922283 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.00911748 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.00905264 |
| VDAC1 | voltage-dependent anion channel 1 | 0.00902338 |
| SECISBP2L | SECIS binding protein 2-like | 0.00892838 |
| PNN | pinin, desmosome associated protein | 0.00891547 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.00880041 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.00879387 |
| FNBP1L | formin binding protein 1-like | 0.00873311 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.00864443 |
| IRF6 | interferon regulatory factor 6 | 0.00860242 |
| TFG | TRK-fused gene | 0.00854552 |
| IL6ST | interleukin 6 signal transducer | 0.00848892 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | 0.00848823 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.00842359 |
| VEGFA | vascular endothelial growth factor A | 0.00842296 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.00834437 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00832561 |
| MYO1B | myosin IB | 0.00829474 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.00828341 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00827971 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00821942 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00820567 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00818641 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.00818288 |
| FNBP1 | formin binding protein 1 | 0.00817866 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.00808829 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.00808307 |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.00804729 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00802266 |
| PRPF38B | pre-mRNA processing factor 38B | 0.00796947 |
| ABI1 | abl-interactor 1 | 0.00795516 |
| TGFB2 | transforming growth factor, beta 2 | 0.00780624 |
| MATR3 | matrin 3 | 0.00776057 |
| MT1E | metallothionein 1E | 0.00774502 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.117998 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0628129 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0624795 |
| LAMB3 | laminin, beta 3 | -0.0602001 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0556742 |
| ASPH | aspartate beta-hydroxylase | -0.0530569 |
| DST | dystonin | -0.0463781 |
| EFNA5 | ephrin-A5 | -0.0456318 |
| LAMC2 | laminin, gamma 2 | -0.0453104 |
| MMP7 | matrix metallopeptidase 7 | -0.0425336 |
| B2M | beta-2-microglobulin | -0.0416766 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0412044 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0398894 |
| ITGA6 | integrin, alpha 6 | -0.0398121 |
| AHNAK | AHNAK nucleoprotein | -0.0396629 |
| RAD51B | RAD51 paralog B | -0.03759 |
| EHBP1 | EH domain binding protein 1 | -0.0375458 |
| RPL23 | ribosomal protein L23 | -0.0357411 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0336888 |
| PTMA | prothymosin, alpha | -0.0329201 |
| LAMA4 | laminin, alpha 4 | -0.0327543 |
| RCOR1 | REST corepressor 1 | -0.0326173 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0318952 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0311023 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0308805 |
| APOL1 | apolipoprotein L, 1 | -0.0304735 |
| CP | ceruloplasmin (ferroxidase) | -0.0299551 |
| PRKCA | protein kinase C, alpha | -0.0298317 |
| RPL19 | ribosomal protein L19 | -0.0297829 |
| PCDH7 | protocadherin 7 | -0.0285691 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0283955 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0281793 |
| DTNA | dystrobrevin, alpha | -0.0281207 |
| RPS21 | ribosomal protein S21 | -0.0280539 |
| RPL35A | ribosomal protein L35a | -0.0278376 |
| NCKAP5 | NCK-associated protein 5 | -0.0275372 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0275314 |
| BCL2L1 | BCL2-like 1 | -0.0273718 |
| SVIL | supervillin | -0.0267823 |
| S100A6 | S100 calcium binding protein A6 | -0.0267817 |
| EGR1 | early growth response 1 | -0.026026 |
| NRG3 | neuregulin 3 | -0.0248502 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0246462 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0246137 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0244519 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0243992 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0242799 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.024271 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.023879 |
| VMP1 | vacuole membrane protein 1 | -0.02368 |
| KRT19 | keratin 19, type I | -0.0235944 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0235809 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0235728 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0232566 |
| MAP1B | microtubule-associated protein 1B | -0.0230406 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0228879 |
| PLAT | plasminogen activator, tissue | -0.0226991 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0225676 |
| MT2A | metallothionein 2A | -0.0225362 |
| VIM | vimentin | -0.0223874 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0222826 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0221141 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0219364 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0219233 |
| FLNB | filamin B, beta | -0.0218864 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0218826 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0214815 |
| RASAL2 | RAS protein activator like 2 | -0.0214279 |
| EZR | ezrin | -0.0210498 |
| FTL | ferritin, light polypeptide | -0.0208079 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0205908 |
| RPS17 | ribosomal protein S17 | -0.0205883 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0205748 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0204751 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0203102 |
| HMGA2 | high mobility group AT-hook 2 | -0.0202433 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0200726 |
| RPS19 | ribosomal protein S19 | -0.0200578 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0200462 |
| OSMR | oncostatin M receptor | -0.0200365 |
| PARD3 | par-3 family cell polarity regulator | -0.0200194 |
| USP34 | ubiquitin specific peptidase 34 | -0.0200058 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0199008 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0198284 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0198239 |
| RAB10 | RAB10, member RAS oncogene family | -0.0196533 |
| MT1X | metallothionein 1X | -0.0195473 |
| RRBP1 | ribosome binding protein 1 | -0.0192306 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0191105 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0190211 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0188742 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0187684 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0184969 |
| RANBP17 | RAN binding protein 17 | -0.0184167 |
| H1-0 | H1.0 linker histone | -0.0182055 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0180794 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0177255 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0177083 |
| RUNX1 | runt-related transcription factor 1 | -0.0176159 |
| RPLP1 | ribosomal protein, large, P1 | -0.0174671 |
