| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.113295 |
| LSAMP | limbic system-associated membrane protein | 0.0770483 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0687027 |
| IGF2 | insulin-like growth factor 2 | 0.0562066 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0476568 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0420495 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0412367 |
| MSI2 | musashi RNA-binding protein 2 | 0.0380763 |
| SMAD6 | SMAD family member 6 | 0.0339839 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0331725 |
| CNTN4 | contactin 4 | 0.0325318 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0323824 |
| SET | SET nuclear proto-oncogene | 0.0316157 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0315246 |
| RNF213 | ring finger protein 213 | 0.0307202 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.030123 |
| CENPF | centromere protein F, 350/400kDa | 0.0299397 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0297607 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0285586 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0269529 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0266487 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0263627 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.026341 |
| TET2 | tet methylcytosine dioxygenase 2 | 0.0261428 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0258862 |
| GSE1 | Gse1 coiled-coil protein | 0.0253315 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0248983 |
| PRKCE | protein kinase C, epsilon | 0.023614 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0234604 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0232023 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0230634 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0230191 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0229104 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0226425 |
| EXOC4 | exocyst complex component 4 | 0.0223153 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0221617 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0221292 |
| CASC3 | cancer susceptibility candidate 3 | 0.0219013 |
| NAV2 | neuron navigator 2 | 0.0211665 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0210635 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0209839 |
| MEIS2 | Meis homeobox 2 | 0.0209626 |
| PRTG | protogenin | 0.0209346 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0208841 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.020495 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0200377 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0198407 |
| CCDC88A | coiled-coil domain containing 88A | 0.0197087 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0196794 |
| ERICH1 | glutamate-rich 1 | 0.019649 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0193904 |
| SSH2 | slingshot protein phosphatase 2 | 0.019279 |
| HELZ | helicase with zinc finger | 0.0192614 |
| CUL1 | cullin 1 | 0.0191747 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0190556 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | 0.0189392 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0189164 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.018903 |
| INSYN2B | inhibitory synaptic factor family member 2B | 0.0188445 |
| RIMBP2 | RIMS binding protein 2 | 0.0187334 |
| IREB2 | iron-responsive element binding protein 2 | 0.0184684 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0184502 |
| NUP153 | nucleoporin 153kDa | 0.0183748 |
| BRD2 | bromodomain containing 2 | 0.0183647 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | 0.0183466 |
| AOPEP | aminopeptidase O (putative) | 0.0182092 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0181149 |
| RC3H1 | ring finger and CCCH-type domains 1 | 0.0180086 |
| CERK | ceramide kinase | 0.0179329 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0177393 |
| RBM6 | RNA binding motif protein 6 | 0.0177362 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0176824 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0175464 |
| MX2 | MX dynamin-like GTPase 2 | 0.0175037 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0174308 |
| HIP1 | huntingtin interacting protein 1 | 0.0174112 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0172609 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0172564 |
| SYNJ2 | synaptojanin 2 | 0.0172185 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0171451 |
| PSEN1 | presenilin 1 | 0.0170719 |
| CTSB | cathepsin B | 0.0169792 |
| SLFN5 | schlafen family member 5 | 0.0166366 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0165396 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0164918 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0164606 |
| DTNA | dystrobrevin, alpha | 0.0164323 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0164183 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0161976 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0160597 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0160124 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0160043 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0159113 |
| RGS4 | regulator of G-protein signaling 4 | 0.0158705 |
| RAB30 | RAB30, member RAS oncogene family | 0.015821 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.0157191 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0157029 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0156594 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0155536 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0154679 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.237559 |
| PTMA | prothymosin, alpha | -0.130698 |
| VIM | vimentin | -0.097606 |
| RPL23 | ribosomal protein L23 | -0.0822521 |
| RPS6 | ribosomal protein S6 | -0.0797776 |
| RPL19 | ribosomal protein L19 | -0.0591434 |
| H3-3B | H3.3 histone B | -0.0590308 |
| TMSB10 | thymosin beta 10 | -0.0588864 |
| RPL34 | ribosomal protein L34 | -0.0588084 |
| RPS24 | ribosomal protein S24 | -0.0566826 |
| RPLP1 | ribosomal protein, large, P1 | -0.0496281 |
| B2M | beta-2-microglobulin | -0.0483353 |
| RPL35A | ribosomal protein L35a | -0.0472557 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0416612 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0407696 |
| COL1A1 | collagen, type I, alpha 1 | -0.0396562 |
| DST | dystonin | -0.0391814 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0386624 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0371709 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0368871 |
| RPLP0 | ribosomal protein, large, P0 | -0.0366921 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0366662 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0364499 |
| RPS12 | ribosomal protein S12 | -0.0362183 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0362058 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0350117 |
| TLE4 | transducin-like enhancer of split 4 | -0.0346146 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0341302 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0338622 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0337038 |
| THBS1 | thrombospondin 1 | -0.0331598 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0328503 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.0327369 |
| RPL32 | ribosomal protein L32 | -0.0326233 |
| TBX2 | T-box 2 | -0.0324826 |
| RPS25 | ribosomal protein S25 | -0.0321024 |
| ACTG1 | actin gamma 1 | -0.0319297 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0319215 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0319208 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0318819 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0312426 |
| RPL38 | ribosomal protein L38 | -0.0309961 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0298433 |
| RPL11 | ribosomal protein L11 | -0.0297955 |
| RPS8 | ribosomal protein S8 | -0.0290764 |
| S100A6 | S100 calcium binding protein A6 | -0.0290238 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0289431 |
| TXNRD1 | thioredoxin reductase 1 | -0.0287 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0283304 |
| RPL12 | ribosomal protein L12 | -0.0283161 |
| RPS11 | ribosomal protein S11 | -0.0282792 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0279061 |
| CADM2 | cell adhesion molecule 2 | -0.0279029 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0278192 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0277966 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0277706 |
| VCL | vinculin | -0.0275939 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0274397 |
| AHNAK | AHNAK nucleoprotein | -0.0272729 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0271322 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0270402 |
| MAP1B | microtubule-associated protein 1B | -0.0267986 |
| RPS23 | ribosomal protein S23 | -0.0267328 |
| RPS5 | ribosomal protein S5 | -0.0265141 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0264624 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0261224 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0259043 |
| S100A9 | S100 calcium binding protein A9 | -0.0258453 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0255871 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0255269 |
| TGFB1 | transforming growth factor, beta 1 | -0.0254853 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0253416 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0251092 |
| VMP1 | vacuole membrane protein 1 | -0.0250547 |
| RPS29 | ribosomal protein S29 | -0.0247798 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0245074 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0244582 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0243047 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0242222 |
| FLNB | filamin B, beta | -0.0241325 |
| IER3 | immediate early response 3 | -0.0239735 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0238666 |
| RPS27 | ribosomal protein S27 | -0.0237725 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0236321 |
| FTL | ferritin, light polypeptide | -0.0235236 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0232401 |
| TOP1 | topoisomerase (DNA) I | -0.0231459 |
| CCDC47 | coiled-coil domain containing 47 | -0.0230798 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0229679 |
| RPLP2 | ribosomal protein, large, P2 | -0.0227981 |
| RGS5 | regulator of G-protein signaling 5 | -0.0227897 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0226836 |
| RPS16 | ribosomal protein S16 | -0.022671 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0225099 |
| RPL31 | ribosomal protein L31 | -0.0221743 |
| TP53 | tumor protein p53 | -0.0221129 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0220288 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0219799 |
| RPS14 | ribosomal protein S14 | -0.0218226 |
| RPL37A | ribosomal protein L37a | -0.0215162 |
