| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.104399 |
| INTS6 | integrator complex subunit 6 | 0.0807685 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0622915 |
| RNF213 | ring finger protein 213 | 0.0547608 |
| SMAD3 | SMAD family member 3 | 0.0478434 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0385595 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0355521 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0334112 |
| RIGI | RNA sensor RIG-I | 0.0301845 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0297763 |
| TNS4 | tensin 4 | 0.0276158 |
| MX1 | MX dynamin-like GTPase 1 | 0.0275475 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0268984 |
| CTBP2 | C-terminal binding protein 2 | 0.0259118 |
| PLSCR2 | phospholipid scramblase 2 | 0.0254695 |
| MLPH | melanophilin | 0.02346 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0225386 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0215474 |
| NABP1 | nucleic acid binding protein 1 | 0.0211245 |
| POU2F2 | POU class 2 homeobox 2 | 0.0205865 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0200428 |
| BCL2L1 | BCL2-like 1 | 0.0194731 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0193942 |
| KIF16B | kinesin family member 16B | 0.0186479 |
| EPHA2 | EPH receptor A2 | 0.0185372 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.018379 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.017784 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0176847 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0173434 |
| FBXO39 | F-box protein 39 | 0.0172418 |
| ANXA2 | annexin A2 | 0.0171552 |
| PRSS22 | protease, serine, 22 | 0.0167834 |
| LRRC8A | leucine rich repeat containing 8 family, member A | 0.0166349 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0166086 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0165418 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0164601 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.0160236 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0156269 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0154671 |
| FHIT | fragile histidine triad | 0.015024 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.015002 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0147383 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0147066 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0146707 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0145713 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0141744 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0138769 |
| EPHB3 | EPH receptor B3 | 0.0138013 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0137164 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0136604 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.013176 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0129965 |
| DHFR | dihydrofolate reductase | 0.0129731 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0128453 |
| POF1B | premature ovarian failure, 1B | 0.0127976 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.012779 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0127509 |
| ARHGAP27 | Rho GTPase activating protein 27 | 0.0127481 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0124673 |
| SEPTIN9 | septin 9 | 0.0124396 |
| VEGFA | vascular endothelial growth factor A | 0.0123769 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 0.0122923 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | 0.0122324 |
| UBAP2 | ubiquitin associated protein 2 | 0.0121811 |
| PLEC | plectin | 0.0120122 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0119981 |
| HOMER1 | homer scaffolding protein 1 | 0.0118363 |
| EFNB2 | ephrin-B2 | 0.0114227 |
| ANKRD18A | ankyrin repeat domain 18A | 0.0113564 |
| HKDC1 | hexokinase domain containing 1 | 0.0113499 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.011183 |
| GON4L | gon-4-like (C. elegans) | 0.0110848 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0110634 |
| EPHB2 | EPH receptor B2 | 0.010968 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0108104 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0107991 |
| TOX3 | TOX high mobility group box family member 3 | 0.0107951 |
| IFI44 | interferon-induced protein 44 | 0.0106838 |
| SDCBP | syndecan binding protein (syntenin) | 0.0106466 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0106379 |
| PRKCE | protein kinase C, epsilon | 0.0106135 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.0105934 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0105246 |
| SKI | SKI proto-oncogene | 0.0102895 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0102452 |
| BCR | breakpoint cluster region | 0.0101297 |
| SZT2 | seizure threshold 2 homolog (mouse) | 0.01003 |
| TPM3 | tropomyosin 3 | 0.0100205 |
| PLSCR1 | phospholipid scramblase 1 | 0.0100109 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00996992 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00996806 |
| KYNU | kynureninase | 0.00995118 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.00994242 |
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) | 0.0098457 |
| RCOR1 | REST corepressor 1 | 0.0098242 |
| TJP1 | tight junction protein 1 | 0.0098233 |
| PRR5L | proline rich 5 like | 0.00977881 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00975339 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.00966349 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.00958946 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.198701 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.192939 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.173683 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.143583 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.131792 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.110725 |
| HLA-B | major histocompatibility complex, class I, B | -0.11017 |
| LCN2 | lipocalin 2 | -0.100248 |
| PTMA | prothymosin, alpha | -0.098145 |
| TXNIP | thioredoxin interacting protein | -0.084377 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0795612 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0771749 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.074972 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0746646 |
| CANX | calnexin | -0.0739386 |
| UBC | ubiquitin C | -0.0723812 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0717408 |
| H1-0 | H1.0 linker histone | -0.0701474 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0689439 |
| PKM | pyruvate kinase, muscle | -0.0660615 |
| RPS6 | ribosomal protein S6 | -0.0633193 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0629143 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.062752 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0625163 |
| PGK1 | phosphoglycerate kinase 1 | -0.062233 |
| AHI1 | Abelson helper integration site 1 | -0.0614174 |
| RUNX1 | runt-related transcription factor 1 | -0.0599696 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0593309 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0569547 |
| PERP | PERP, TP53 apoptosis effector | -0.0569348 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0566286 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0559344 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0558386 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0557022 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0534158 |
| EPCAM | epithelial cell adhesion molecule | -0.0530438 |
| ENO1 | enolase 1, (alpha) | -0.0527087 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0497224 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0489674 |
| HLA-E | major histocompatibility complex, class I, E | -0.0482851 |
| PATJ | PATJ crumbs cell polarity complex component | -0.047493 |
| DSTN | destrin (actin depolymerizing factor) | -0.0472196 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0471626 |
| CALR | calreticulin | -0.0460672 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.046039 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0452525 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0442605 |
| NCKAP5 | NCK-associated protein 5 | -0.0440485 |
| RRBP1 | ribosome binding protein 1 | -0.0438589 |
| ZNF292 | zinc finger protein 292 | -0.0435889 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0435878 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0434893 |
| NDRG1 | N-myc downstream regulated 1 | -0.0419488 |
| LDHA | lactate dehydrogenase A | -0.0417978 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0417854 |
| ABLIM1 | actin binding LIM protein 1 | -0.0417464 |
| RPLP1 | ribosomal protein, large, P1 | -0.041113 |
| GOLGB1 | golgin B1 | -0.0407116 |
| HLA-A | major histocompatibility complex, class I, A | -0.040085 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0395976 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0391001 |
| HLA-C | major histocompatibility complex, class I, C | -0.0389719 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0388072 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0385107 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0380223 |
| IRF1 | interferon regulatory factor 1 | -0.0377947 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0375968 |
| LYZ | lysozyme | -0.0370007 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0366964 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0366809 |
| IFNGR1 | interferon gamma receptor 1 | -0.0365654 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0361375 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0357769 |
| XAF1 | XIAP associated factor 1 | -0.0353393 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0349507 |
| GOLGA4 | golgin A4 | -0.0348506 |
| EZR | ezrin | -0.0348122 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0347338 |
| DIAPH3 | diaphanous-related formin 3 | -0.0346237 |
| TMSB10 | thymosin beta 10 | -0.0338226 |
| ARF1 | ADP-ribosylation factor 1 | -0.0337381 |
| RPL34 | ribosomal protein L34 | -0.0335297 |
| APOL1 | apolipoprotein L, 1 | -0.0334355 |
| SBF2 | SET binding factor 2 | -0.0334109 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0332562 |
| TRIM2 | tripartite motif containing 2 | -0.0331914 |
| RBM39 | RNA binding motif protein 39 | -0.0331898 |
| MKI67 | marker of proliferation Ki-67 | -0.0324917 |
| EHF | ets homologous factor | -0.032382 |
| RPL19 | ribosomal protein L19 | -0.0323235 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0322628 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0321391 |
| MYO1E | myosin IE | -0.0319786 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0319295 |
| RPL12 | ribosomal protein L12 | -0.0318696 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0318081 |
| GNAS | GNAS complex locus | -0.0317771 |
| SLC38A1 | solute carrier family 38, member 1 | -0.031735 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0316335 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0313444 |
