| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.353195 |
| PLEC | plectin | 0.0556054 |
| NDRG1 | N-myc downstream regulated 1 | 0.054174 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0536149 |
| LOC112694756 | uncharaterized LOC112694756 | 0.051663 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0475887 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0393811 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0368007 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0362538 |
| FAM13A | family with sequence similarity 13, member A | 0.0360054 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0358228 |
| VEGFA | vascular endothelial growth factor A | 0.0338765 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0315229 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.030053 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0283196 |
| CALR | calreticulin | 0.0261505 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0248871 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0235718 |
| DTNA | dystrobrevin, alpha | 0.0233996 |
| RPL3 | ribosomal protein L3 | 0.0231634 |
| FLNA | filamin A, alpha | 0.0225557 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0224844 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0221 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0220851 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0220834 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0217651 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0216702 |
| ZNF841 | zinc finger protein 841 | 0.0215223 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0213885 |
| HLA-A | major histocompatibility complex, class I, A | 0.0210554 |
| COL5A1 | collagen, type V, alpha 1 | 0.0209876 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0209237 |
| FAM219A | family with sequence similarity 219, member A | 0.0208562 |
| C1S | complement component 1, s subcomponent | 0.0206108 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0196311 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0194864 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0194804 |
| YBX1 | Y box binding protein 1 | 0.0194661 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0194378 |
| BRD2 | bromodomain containing 2 | 0.0192184 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0176184 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0175913 |
| NUP58 | nucleoporin 58 | 0.0173369 |
| ARRDC3 | arrestin domain containing 3 | 0.0172384 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0168497 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0164345 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0158329 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0158087 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0157953 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.015766 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0154973 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0154094 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0148573 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0146532 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0146454 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0140248 |
| HYOU1 | hypoxia up-regulated 1 | 0.0139618 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0139231 |
| FAM162A | family with sequence similarity 162, member A | 0.0138775 |
| HELZ | helicase with zinc finger | 0.0136451 |
| PER1 | period circadian clock 1 | 0.0136114 |
| FGF13 | fibroblast growth factor 13 | 0.0135905 |
| SRP54 | signal recognition particle 54kDa | 0.0134303 |
| ZNF160 | zinc finger protein 160 | 0.0131877 |
| FN1 | fibronectin 1 | 0.0130699 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0129357 |
| ANKRD37 | ankyrin repeat domain 37 | 0.0129019 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0128515 |
| PCBP2 | poly(rC) binding protein 2 | 0.0126874 |
| ADM | adrenomedullin | 0.0126398 |
| DIPK2A | divergent protein kinase domain 2A | 0.0125768 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0121864 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0119547 |
| GYS1 | glycogen synthase 1 (muscle) | 0.011954 |
| TGFB1 | transforming growth factor, beta 1 | 0.0119406 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0119381 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0117913 |
| TFG | TRK-fused gene | 0.0117843 |
| LRRC23 | leucine rich repeat containing 23 | 0.0117152 |
| PYGL | phosphorylase, glycogen, liver | 0.0116924 |
| RACK1 | receptor for activated C kinase 1 | 0.0116237 |
| RPS2 | ribosomal protein S2 | 0.0115511 |
| TAPBP | TAP binding protein (tapasin) | 0.0115299 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0114825 |
| C1D | C1D nuclear receptor corepressor | 0.0113684 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0113388 |
| RCOR1 | REST corepressor 1 | 0.0113334 |
| PGM3 | phosphoglucomutase 3 | 0.0113277 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.01131 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0112364 |
| TFRC | transferrin receptor | 0.0111365 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0111252 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0111143 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0109579 |
| MRC2 | mannose receptor, C type 2 | 0.0108944 |
| H2AC6 | H2A clustered histone 6 | 0.0108797 |
| MED26 | mediator complex subunit 26 | 0.0108011 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0107461 |
| IGF2 | insulin-like growth factor 2 | 0.0107444 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0106866 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.196434 |
| FNDC3B | fibronectin type III domain containing 3B | -0.13552 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.125838 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.103985 |
| CD44 | CD44 molecule (Indian blood group) | -0.0927394 |
| VIM | vimentin | -0.0866627 |
| MAP1B | microtubule-associated protein 1B | -0.0798559 |
| ASPH | aspartate beta-hydroxylase | -0.0775183 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0702412 |
| GLIS3 | GLIS family zinc finger 3 | -0.0691491 |
| SBF2 | SET binding factor 2 | -0.0680159 |
| TPM4 | tropomyosin 4 | -0.0675423 |
| TMSB10 | thymosin beta 10 | -0.0663259 |
| DST | dystonin | -0.0652686 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0649943 |
| PTMA | prothymosin, alpha | -0.0632217 |
| NLGN1 | neuroligin 1 | -0.0624098 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0577724 |
| OSMR | oncostatin M receptor | -0.0556551 |
| RTN4 | reticulon 4 | -0.0551368 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0538254 |
| TNNC1 | troponin C type 1 (slow) | -0.0517821 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.051124 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0494045 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0491002 |
| FTL | ferritin, light polypeptide | -0.0482362 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0481573 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0479845 |
| TNS3 | tensin 3 | -0.0478632 |
| ATXN1 | ataxin 1 | -0.0474176 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0473884 |
| PGK1 | phosphoglycerate kinase 1 | -0.0463445 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0462897 |
| TXNRD1 | thioredoxin reductase 1 | -0.0462445 |
| KYNU | kynureninase | -0.0446944 |
| CALD1 | caldesmon 1 | -0.0442209 |
| VCL | vinculin | -0.0441416 |
| ENO1 | enolase 1, (alpha) | -0.0438378 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0432282 |
| STK17A | serine/threonine kinase 17a | -0.0431959 |
| LDHA | lactate dehydrogenase A | -0.0428195 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0424 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0421606 |
| INHBA | inhibin, beta A | -0.0418494 |
| PHF14 | PHD finger protein 14 | -0.0414478 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0411652 |
| LRRC49 | leucine rich repeat containing 49 | -0.0410008 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0408312 |
| NAV3 | neuron navigator 3 | -0.0407811 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0407254 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0396562 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0395137 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0391618 |
| ANKRD11 | ankyrin repeat domain 11 | -0.037683 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0376315 |
| EGFR | epidermal growth factor receptor | -0.0367512 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.035978 |
| USP47 | ubiquitin specific peptidase 47 | -0.0353333 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0348999 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.034529 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.034404 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0343751 |
| NF1 | neurofibromin 1 | -0.0339554 |
| TUBA1B | tubulin, alpha 1b | -0.0339435 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0337163 |
| IL6ST | interleukin 6 signal transducer | -0.0335978 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0335591 |
| VMP1 | vacuole membrane protein 1 | -0.032808 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0327748 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0327605 |
| TNPO1 | transportin 1 | -0.0324634 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0324403 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0321379 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0320834 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0319512 |
| TUBB | tubulin, beta class I | -0.0313838 |
| CENPF | centromere protein F, 350/400kDa | -0.0308295 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0307232 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0298414 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0298398 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0297764 |
| SYT1 | synaptotagmin I | -0.0296583 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0295776 |
| TENM3 | teneurin transmembrane protein 3 | -0.0294051 |
| CANX | calnexin | -0.0291834 |
| POTEF | POTE ankyrin domain family, member F | -0.028474 |
| CDK6 | cyclin-dependent kinase 6 | -0.0281788 |
| CENPE | centromere protein E, 312kDa | -0.0281032 |
| JMJD1C | jumonji domain containing 1C | -0.0277738 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0277167 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0273626 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0272992 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.026974 |
| RPS6 | ribosomal protein S6 | -0.0267577 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0266899 |
| USP34 | ubiquitin specific peptidase 34 | -0.026519 |
| COG5 | component of oligomeric golgi complex 5 | -0.0264243 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.026362 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0263607 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0263163 |
