| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Elagolix sodium_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNA | filamin A, alpha | 0.0922229 |
| ACTG1 | actin gamma 1 | 0.0872177 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0600243 |
| PLEC | plectin | 0.057465 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0552911 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0542244 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.041302 |
| INTS6 | integrator complex subunit 6 | 0.0404533 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0358374 |
| PAX8 | paired box 8 | 0.0354555 |
| KRT86 | keratin 86, type II | 0.0336843 |
| HLA-C | major histocompatibility complex, class I, C | 0.0322738 |
| PRELID2 | PRELI domain containing 2 | 0.0309018 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0306243 |
| NDRG1 | N-myc downstream regulated 1 | 0.028327 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0278397 |
| CLDN4 | claudin 4 | 0.0256721 |
| EGFR | epidermal growth factor receptor | 0.023947 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0234191 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0233131 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0231295 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0229754 |
| RAD51B | RAD51 paralog B | 0.0228276 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0225724 |
| LAMA5 | laminin, alpha 5 | 0.0222113 |
| MYEOV | myeloma overexpressed | 0.0219646 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0212038 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.020909 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0204044 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0203637 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0202238 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0201566 |
| RACK1 | receptor for activated C kinase 1 | 0.020108 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0186104 |
| AEBP2 | AE binding protein 2 | 0.0185219 |
| ATXN1 | ataxin 1 | 0.0182199 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.017987 |
| AGRN | agrin | 0.0178306 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0171537 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0169995 |
| RNF213 | ring finger protein 213 | 0.0169895 |
| RUNX1 | runt-related transcription factor 1 | 0.0167425 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0162679 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0162205 |
| HMGA2 | high mobility group AT-hook 2 | 0.0161645 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.0161057 |
| CMIP | c-Maf inducing protein | 0.0160407 |
| EPHA2 | EPH receptor A2 | 0.0155051 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0154366 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0147843 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0144254 |
| ACTN4 | actinin, alpha 4 | 0.0143468 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.014291 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0142726 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.014117 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0140357 |
| RCOR1 | REST corepressor 1 | 0.0136501 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.013516 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0134901 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0132948 |
| STC2 | stanniocalcin 2 | 0.0132121 |
| SHISA5 | shisa family member 5 | 0.0130623 |
| ACTN1 | actinin, alpha 1 | 0.0129654 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.012952 |
| UBAP2 | ubiquitin associated protein 2 | 0.0127567 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0127189 |
| CAPN1 | calpain 1, (mu/I) large subunit | 0.0126886 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0126592 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 | 0.0126504 |
| TFDP1 | transcription factor Dp-1 | 0.0125925 |
| GPATCH2L | G patch domain containing 2-like | 0.0125468 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0123161 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0122134 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0118625 |
| NBEAL2 | neurobeachin-like 2 | 0.0116537 |
| TAPBP | TAP binding protein (tapasin) | 0.0116529 |
| CFAP44 | cilia and flagella associated protein 44 | 0.0115811 |
| ALS2CL | ALS2 C-terminal like | 0.0114016 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0113278 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.011274 |
| PCBD2 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 | 0.0112336 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0112194 |
| RBM12B | RNA binding motif protein 12B | 0.0112156 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0111639 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.0111134 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0110795 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0110184 |
| FAT1 | FAT atypical cadherin 1 | 0.0109902 |
| RARA | retinoic acid receptor, alpha | 0.0108886 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0108357 |
| SGMS2 | sphingomyelin synthase 2 | 0.0107897 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0106748 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0106261 |
| HDAC4 | histone deacetylase 4 | 0.0105005 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 0.0104861 |
| MYH15 | myosin, heavy chain 15 | 0.0104464 |
| MIPEP | mitochondrial intermediate peptidase | 0.0104262 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0104057 |
| SURF4 | surfeit 4 | 0.0102551 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0102084 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.191927 |
| PTMA | prothymosin, alpha | -0.123662 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.109038 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0921998 |
| GOLGA4 | golgin A4 | -0.0893401 |
| RPS6 | ribosomal protein S6 | -0.0882693 |
| APP | amyloid beta (A4) precursor protein | -0.0784855 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0703871 |
| ZNF292 | zinc finger protein 292 | -0.064009 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0636169 |
| MKI67 | marker of proliferation Ki-67 | -0.0622937 |
| MAP4 | microtubule-associated protein 4 | -0.0599733 |
| SETD5 | SET domain containing 5 | -0.0592492 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0584918 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.058423 |
| SBF2 | SET binding factor 2 | -0.0565994 |
| FTL | ferritin, light polypeptide | -0.0563794 |
| MATR3 | matrin 3 | -0.0562549 |
| AHNAK | AHNAK nucleoprotein | -0.0544594 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0525307 |
| TMSB4X | thymosin beta 4, X-linked | -0.0512864 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0510638 |
| ASPH | aspartate beta-hydroxylase | -0.0503917 |
| PGK1 | phosphoglycerate kinase 1 | -0.0484927 |
| OGA | O-GlcNAcase | -0.0482914 |
| ANLN | anillin, actin binding protein | -0.0475754 |
| JMJD1C | jumonji domain containing 1C | -0.047371 |
| RPS24 | ribosomal protein S24 | -0.0473463 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0466051 |
| RBM39 | RNA binding motif protein 39 | -0.0464419 |
| RPL32 | ribosomal protein L32 | -0.0450329 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.044693 |
| RPL19 | ribosomal protein L19 | -0.0446564 |
| NF1 | neurofibromin 1 | -0.0441487 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0436405 |
| S100A10 | S100 calcium binding protein A10 | -0.0434545 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0433518 |
| SETD2 | SET domain containing 2 | -0.0428985 |
| TXNRD1 | thioredoxin reductase 1 | -0.0426469 |
| SEPTIN7 | septin 7 | -0.0426032 |
| CDCP1 | CUB domain containing protein 1 | -0.042265 |
| RPS2 | ribosomal protein S2 | -0.0421028 |
| SSH2 | slingshot protein phosphatase 2 | -0.0419521 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0416253 |
| NKTR | natural killer cell triggering receptor | -0.0414284 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0402117 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0400628 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0399836 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0399064 |
| PKM | pyruvate kinase, muscle | -0.0398514 |
| RLF | rearranged L-myc fusion | -0.0395358 |
| RPS8 | ribosomal protein S8 | -0.0392998 |
| DSG2 | desmoglein 2 | -0.0392817 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0392547 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0389799 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0387128 |
| RPL7A | ribosomal protein L7a | -0.0385754 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0384797 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0380649 |
| RPL12 | ribosomal protein L12 | -0.0379894 |
| CANX | calnexin | -0.0376686 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0376362 |
| RPL28 | ribosomal protein L28 | -0.0372166 |
| USP34 | ubiquitin specific peptidase 34 | -0.0368584 |
| FUS | FUS RNA binding protein | -0.0365261 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0362937 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0362841 |
| B2M | beta-2-microglobulin | -0.0359707 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0359154 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0358539 |
| TMSB10 | thymosin beta 10 | -0.0356372 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0355107 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0353477 |
| RPLP2 | ribosomal protein, large, P2 | -0.0352242 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0351727 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0347343 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0343071 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0342443 |
| H1-0 | H1.0 linker histone | -0.0341599 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.034147 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0337178 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0337086 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0336467 |
| CD2AP | CD2-associated protein | -0.0335523 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0335299 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0335265 |
| BBX | bobby sox homolog (Drosophila) | -0.0333493 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.033131 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0329501 |
| PTK2 | protein tyrosine kinase 2 | -0.0324778 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0324498 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0320422 |
| KIF5B | kinesin family member 5B | -0.0319429 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0317988 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0317592 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.031514 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0313988 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.031383 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0311953 |
| RPS11 | ribosomal protein S11 | -0.0311021 |
