| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL5A1 | collagen, type V, alpha 1 | 0.0936701 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0837465 |
| HMGA2 | high mobility group AT-hook 2 | 0.0714915 |
| NAV1 | neuron navigator 1 | 0.0669584 |
| PLEC | plectin | 0.0589296 |
| ACTG1 | actin gamma 1 | 0.0570455 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0538865 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0466765 |
| FLNA | filamin A, alpha | 0.0439846 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0434982 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0431409 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0419775 |
| MLPH | melanophilin | 0.0391664 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0354496 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0321503 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0303213 |
| COL7A1 | collagen, type VII, alpha 1 | 0.029876 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0297947 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0296428 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0277816 |
| ANXA2 | annexin A2 | 0.0270869 |
| MT2A | metallothionein 2A | 0.0264762 |
| HSPA8 | heat shock 70kDa protein 8 | 0.025253 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0250445 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.024902 |
| GLIS3 | GLIS family zinc finger 3 | 0.0248273 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0237157 |
| EGFR | epidermal growth factor receptor | 0.0235571 |
| HLA-C | major histocompatibility complex, class I, C | 0.0235121 |
| IL11 | interleukin 11 | 0.0234653 |
| RPS27A | ribosomal protein S27a | 0.0226047 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0224567 |
| SEPTIN9 | septin 9 | 0.0211546 |
| UBC | ubiquitin C | 0.0211388 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0207402 |
| ENO1 | enolase 1, (alpha) | 0.0207247 |
| CAPRIN2 | caprin family member 2 | 0.0206887 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0204651 |
| MT1E | metallothionein 1E | 0.020455 |
| PDLIM4 | PDZ and LIM domain 4 | 0.0202645 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0201791 |
| RPS3 | ribosomal protein S3 | 0.019397 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0193574 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0191656 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.0191608 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0190412 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0190218 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0184761 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0183448 |
| SMAD3 | SMAD family member 3 | 0.0183258 |
| PODXL | podocalyxin-like | 0.018232 |
| ACTN1 | actinin, alpha 1 | 0.0181384 |
| VEGFA | vascular endothelial growth factor A | 0.0180393 |
| FAT1 | FAT atypical cadherin 1 | 0.0179842 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0179593 |
| EFNA5 | ephrin-A5 | 0.0177223 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0171963 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0170456 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0170437 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0166265 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.016595 |
| VIM | vimentin | 0.0162028 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.016174 |
| PCBP2 | poly(rC) binding protein 2 | 0.0158911 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0157476 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0157337 |
| TNS1 | tensin 1 | 0.0157021 |
| RACK1 | receptor for activated C kinase 1 | 0.0154699 |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.0154505 |
| FRMD4A | FERM domain containing 4A | 0.0153245 |
| MRC2 | mannose receptor, C type 2 | 0.0151879 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0149379 |
| INTS6 | integrator complex subunit 6 | 0.0148883 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0148206 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0140779 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0139967 |
| ANGPTL4 | angiopoietin-like 4 | 0.013985 |
| WDR27 | WD repeat domain 27 | 0.0138829 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0137385 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0136468 |
| SMTN | smoothelin | 0.0134789 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0134696 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0134074 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.013315 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0132267 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0131272 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0131176 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0129744 |
| JAG1 | jagged 1 | 0.0129278 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0129042 |
| TPM3 | tropomyosin 3 | 0.0127129 |
| AGO2 | argonaute RISC catalytic component 2 | 0.012635 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0125932 |
| RRM2 | ribonucleotide reductase M2 | 0.0123524 |
| CMIP | c-Maf inducing protein | 0.012351 |
| L1CAM | L1 cell adhesion molecule | 0.0123282 |
| ZNF638 | zinc finger protein 638 | 0.0122663 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0122487 |
| WWOX | WW domain containing oxidoreductase | 0.0122455 |
| SH2B3 | SH2B adaptor protein 3 | 0.0120076 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.405373 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.133819 |
| FNDC3B | fibronectin type III domain containing 3B | -0.120586 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.118908 |
| FN1 | fibronectin 1 | -0.110425 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.100428 |
| PTMA | prothymosin, alpha | -0.0980646 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0892417 |
| FAM13A | family with sequence similarity 13, member A | -0.0763334 |
| PGK1 | phosphoglycerate kinase 1 | -0.0739976 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0694143 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0692278 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0672548 |
| CDCP1 | CUB domain containing protein 1 | -0.0572986 |
| CANX | calnexin | -0.0539001 |
| GOLGA4 | golgin A4 | -0.0534742 |
| SPAG9 | sperm associated antigen 9 | -0.0505516 |
| CENPF | centromere protein F, 350/400kDa | -0.0505129 |
| TMSB10 | thymosin beta 10 | -0.0503592 |
| LOX | lysyl oxidase | -0.0494835 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.046272 |
| RRBP1 | ribosome binding protein 1 | -0.0456646 |
| ZNF292 | zinc finger protein 292 | -0.04454 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0439411 |
| RBM39 | RNA binding motif protein 39 | -0.0437821 |
| SETD5 | SET domain containing 5 | -0.043091 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0414402 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0410704 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0402883 |
| SBF2 | SET binding factor 2 | -0.0402425 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0398153 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0393131 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0389631 |
| NDRG1 | N-myc downstream regulated 1 | -0.0381161 |
| RLF | rearranged L-myc fusion | -0.0375033 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0360936 |
| MORF4L2 | mortality factor 4 like 2 | -0.0358008 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0357661 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0355403 |
| ADM | adrenomedullin | -0.0342023 |
| PDE10A | phosphodiesterase 10A | -0.0339875 |
| RPS6 | ribosomal protein S6 | -0.0327123 |
| PKM | pyruvate kinase, muscle | -0.0321404 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0318872 |
| FTL | ferritin, light polypeptide | -0.0316925 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0315109 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0313283 |
| NGLY1 | N-glycanase 1 | -0.031323 |
| TPX2 | TPX2, microtubule-associated | -0.0312538 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0306726 |
| RNF24 | ring finger protein 24 | -0.0301892 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0298282 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0295728 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0294628 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0291486 |
| GLG1 | golgi glycoprotein 1 | -0.0291345 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.028482 |
| MAP1B | microtubule-associated protein 1B | -0.0284137 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0275884 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0275482 |
| CLTC | clathrin, heavy chain (Hc) | -0.027373 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0266214 |
| TENM2 | teneurin transmembrane protein 2 | -0.0265002 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0264467 |
| SEC24A | SEC24 family member A | -0.026239 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0260934 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0260096 |
| USP3 | ubiquitin specific peptidase 3 | -0.0259264 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0257468 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0254269 |
| HELZ | helicase with zinc finger | -0.0254174 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0252524 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0250146 |
| TUBB6 | tubulin, beta 6 class V | -0.0247743 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0244365 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0243433 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0242063 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0239039 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0237742 |
| FSTL1 | follistatin-like 1 | -0.0237574 |
| ANLN | anillin, actin binding protein | -0.0235608 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0235324 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0234974 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0233929 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0233685 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0232595 |
| CDH13 | cadherin 13 | -0.0231612 |
| COPA | coatomer protein complex, subunit alpha | -0.0231429 |
| FOXJ3 | forkhead box J3 | -0.0231258 |
| MKI67 | marker of proliferation Ki-67 | -0.0230495 |
| MIMS1 | mitochondrial inner membrane scaffold 1 | -0.0228609 |
| CD109 | CD109 molecule | -0.0228605 |
| OGA | O-GlcNAcase | -0.0227194 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0226455 |
| SFTPA2 | surfactant protein A2 | -0.0226032 |
| TAOK1 | TAO kinase 1 | -0.0222872 |
| S100A10 | S100 calcium binding protein A10 | -0.0222177 |
| DST | dystonin | -0.0221693 |
| USP34 | ubiquitin specific peptidase 34 | -0.022161 |
| NUP58 | nucleoporin 58 | -0.0220021 |
