| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Elagolix sodium perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Elagolix sodium_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0697723 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0681497 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0675947 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0589858 |
| FRY | furry homolog (Drosophila) | 0.0509633 |
| NDRG1 | N-myc downstream regulated 1 | 0.0498237 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0447313 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.039414 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0392631 |
| ACTG1 | actin gamma 1 | 0.0376183 |
| LAMA4 | laminin, alpha 4 | 0.0370578 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.036331 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0344642 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0339342 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0330038 |
| KRT20 | keratin 20, type I | 0.0326508 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0314522 |
| MMP7 | matrix metallopeptidase 7 | 0.0307062 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0304539 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0300009 |
| EGR1 | early growth response 1 | 0.0298866 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0298587 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0293832 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.027842 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.0273535 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0269064 |
| DIAPH2 | diaphanous-related formin 2 | 0.0263318 |
| RAD51B | RAD51 paralog B | 0.0251866 |
| RNF213 | ring finger protein 213 | 0.025015 |
| TMEM45B | transmembrane protein 45B | 0.0247056 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0242203 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.023647 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0234038 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0232875 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0229094 |
| KLF13 | Kruppel-like factor 13 | 0.0226058 |
| LAMB3 | laminin, beta 3 | 0.0222995 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0218476 |
| TNS1 | tensin 1 | 0.0217336 |
| LAMA5 | laminin, alpha 5 | 0.0213244 |
| HKDC1 | hexokinase domain containing 1 | 0.0207966 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.0206321 |
| PLEC | plectin | 0.0204328 |
| PRR5L | proline rich 5 like | 0.0203795 |
| TMC5 | transmembrane channel-like 5 | 0.0201713 |
| RPL35A | ribosomal protein L35a | 0.0198122 |
| HMGA2 | high mobility group AT-hook 2 | 0.0195327 |
| POF1B | premature ovarian failure, 1B | 0.0195219 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0193924 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0190432 |
| PCED1B | PC-esterase domain containing 1B | 0.018947 |
| KLK10 | kallikrein-related peptidase 10 | 0.0187997 |
| CAPN8 | calpain 8 | 0.0182869 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0182379 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0181745 |
| TNS4 | tensin 4 | 0.0178794 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0178556 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0176267 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0173562 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0172809 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.017248 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.017049 |
| MGLL | monoglyceride lipase | 0.0168859 |
| WWOX | WW domain containing oxidoreductase | 0.0168127 |
| VEGFA | vascular endothelial growth factor A | 0.0165789 |
| KLF10 | Kruppel-like factor 10 | 0.0160247 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 0.0157509 |
| PYGB | phosphorylase, glycogen; brain | 0.0153897 |
| MCL1 | myeloid cell leukemia 1 | 0.0153882 |
| SULF2 | sulfatase 2 | 0.0152948 |
| TRIB1 | tribbles pseudokinase 1 | 0.0152479 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0152154 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0151391 |
| HLA-C | major histocompatibility complex, class I, C | 0.0146891 |
| CFAP44 | cilia and flagella associated protein 44 | 0.0140247 |
| KRT19 | keratin 19, type I | 0.0134167 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0133649 |
| NPSR1 | neuropeptide S receptor 1 | 0.0133133 |
| TP53I11 | tumor protein p53 inducible protein 11 | 0.0132718 |
| EXOC4 | exocyst complex component 4 | 0.0132455 |
| EPS8L1 | EPS8-like 1 | 0.0132292 |
| MYEOV | myeloma overexpressed | 0.0130252 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0126793 |
| LCN2 | lipocalin 2 | 0.0126104 |
| CA12 | carbonic anhydrase XII | 0.0125679 |
| EGFR | epidermal growth factor receptor | 0.0125621 |
| CUX1 | cut-like homeobox 1 | 0.0125126 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0125012 |
| SACK1E | scaffolding CK1 anchoring protein E | 0.0124242 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.0123838 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0122119 |
| GTPBP2 | GTP binding protein 2 | 0.0120291 |
| RPS3 | ribosomal protein S3 | 0.0120125 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 | 0.0119452 |
| ITGA1 | integrin, alpha 1 | 0.0119201 |
| APOL1 | apolipoprotein L, 1 | 0.0118988 |
| AGRN | agrin | 0.0118701 |
| WNT2B | wingless-type MMTV integration site family, member 2B | 0.0118419 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0118183 |
| ASS1 | argininosuccinate synthase 1 | 0.0117942 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.184675 |
| TXNRD1 | thioredoxin reductase 1 | -0.134144 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.132412 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0923124 |
| RPS6 | ribosomal protein S6 | -0.0914247 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0889211 |
| PTMA | prothymosin, alpha | -0.087745 |
| GOLGA4 | golgin A4 | -0.0855995 |
| FTL | ferritin, light polypeptide | -0.0833655 |
| JMJD1C | jumonji domain containing 1C | -0.0776358 |
| RBM39 | RNA binding motif protein 39 | -0.0770434 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0759793 |
| LMO7 | LIM domain 7 | -0.0755983 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0743053 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.07262 |
| TJP1 | tight junction protein 1 | -0.069288 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0687604 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0671971 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.06669 |
| PTK2 | protein tyrosine kinase 2 | -0.0664312 |
| EZR | ezrin | -0.0636512 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0629387 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0622259 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0614009 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0601551 |
| SBF2 | SET binding factor 2 | -0.0597926 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0569473 |
| OGA | O-GlcNAcase | -0.0562624 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.055455 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0554457 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0552099 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.054178 |
| CANX | calnexin | -0.054072 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0539635 |
| USP34 | ubiquitin specific peptidase 34 | -0.0513966 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0513066 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.050965 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0508572 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0502466 |
| RPS2 | ribosomal protein S2 | -0.0500662 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0491393 |
| RPS19 | ribosomal protein S19 | -0.0489096 |
| TOP1 | topoisomerase (DNA) I | -0.0487065 |
| COG5 | component of oligomeric golgi complex 5 | -0.0474924 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0468927 |
| ZNF292 | zinc finger protein 292 | -0.0466596 |
| CLTC | clathrin, heavy chain (Hc) | -0.0457572 |
| NF1 | neurofibromin 1 | -0.0454951 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0448847 |
| RPS5 | ribosomal protein S5 | -0.0448091 |
| SUCO | SUN domain containing ossification factor | -0.0445682 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0444505 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0440719 |
| HELZ | helicase with zinc finger | -0.0433854 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0430901 |
| MORF4L2 | mortality factor 4 like 2 | -0.0430769 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0430497 |
| TES | testin LIM domain protein | -0.0430279 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0430096 |
| RPL28 | ribosomal protein L28 | -0.0428559 |
| RPLP2 | ribosomal protein, large, P2 | -0.0428552 |
| RPLP1 | ribosomal protein, large, P1 | -0.0425469 |
| RPS11 | ribosomal protein S11 | -0.0424187 |
| SPAG9 | sperm associated antigen 9 | -0.0422619 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0421987 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0420534 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0416859 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0416715 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0409201 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.040679 |
| RPL21 | ribosomal protein L21 | -0.0405362 |
| CD2AP | CD2-associated protein | -0.0404012 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0396782 |
| CCNL1 | cyclin L1 | -0.0396752 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0393031 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0392883 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.038856 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0388292 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0387907 |
| USP3 | ubiquitin specific peptidase 3 | -0.0387097 |
| PDS5B | PDS5 cohesin associated factor B | -0.038298 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0382613 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0373731 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0373517 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0373147 |
| RHEB | Ras homolog enriched in brain | -0.036814 |
| POTEF | POTE ankyrin domain family, member F | -0.0367904 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0365625 |
| IPO7 | importin 7 | -0.0365369 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0365005 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0363266 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0358869 |
| RPS21 | ribosomal protein S21 | -0.0356122 |
| LDHA | lactate dehydrogenase A | -0.0355082 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0354014 |
| THOC2 | THO complex 2 | -0.0353527 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0353265 |
| VMP1 | vacuole membrane protein 1 | -0.0352237 |
| MKI67 | marker of proliferation Ki-67 | -0.0351188 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0347141 |
